{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:30:53Z","timestamp":1787758253611,"version":"build-2784847793"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Although the routine use of alkali buffer is not recommended in patients with respiratory acidosis, some patients may benefit from its administration. A 42-year-old man was treated with venovenous extracorporeal membrane oxygenation (VV-ECMO) and continuous venovenous hemodiafiltration (CVVHDF) due to necrotizing pneumonia and emphysematous cystitis with\n                      <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                      . Although the sweep gas flow rate of the VV-ECMO was gradually reduced, he failed to wean off VV-ECMO due to respiratory acidosis, followed by tachycardia and tachypnea on the 63rd day of VV-ECMO. Therefore, we mixed sodium bicarbonate in the replacement fluid of CVVHDF for 5 days to avoid an intolerable decrease in blood pH after discontinuing the VV-ECMO sweep gas. When the serum bicarbonate concentration was &gt;30 mmol\/L and pH was maintained at &gt;7.30 with a PCO2 of &gt;60 mmHg, VV-ECMO was finally decannulated. Sodium bicarbonate buffer through the replacement of CVVHDF fluid facilitated VV-ECMO weaning in a patient with hypercapnic respiratory failure.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/atm.atm_265_22","type":"journal-article","created":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T02:29:39Z","timestamp":1665109779000},"page":"237-240","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Sodium bicarbonate buffer for weaning from venovenous extracorporeal membrane oxygenation in patients with hypercapnic respiratory failure and acute renal failure"],"prefix":"10.4103","volume":"17","author":[{"given":"Sua","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinwook","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Je Hyeong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20240830","first-page":"366","article-title":"Respiratory acidosis","volume":"46","author":"Epstein","year":"2001","journal-title":"Respir Care"},{"key":"R2-9-20240830","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s00134-003-2051-1","article-title":"Permissive hypercapnia-role in protective lung ventilatory strategies","volume":"30","author":"Laffey","year":"2004","journal-title":"Intensive Care Med"},{"key":"R3-9-20240830","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1053\/j.ajkd.2019.05.029","article-title":"Alkali therapy for respiratory acidosis: A medical controversy","volume":"75","author":"Adrogu\u00e9","year":"2020","journal-title":"Am J Kidney Dis"},{"key":"R4-9-20240830","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/MNH.0000000000000687","article-title":"Sodium bicarbonate therapy for acute respiratory acidosis","volume":"30","author":"Chand","year":"2021","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"R5-9-20240830","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.ekir.2018.06.001","article-title":"Secondary response to chronic respiratory acidosis in humans: A prospective study","volume":"3","author":"Gonz\u00e1lez","year":"2018","journal-title":"Kidney Int Rep"}],"container-title":["Annals of Thoracic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/atm.atm_265_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:10:51Z","timestamp":1787757051000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/atm.atm_265_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/atm.atm_265_22","relation":{},"ISSN":["1817-1737"],"issn-type":[{"value":"1817-1737","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}