{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:23:41Z","timestamp":1787757821197,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Hypogammaglobulinemia is a heterogeneous group of innate and acquired antibody deficiency with variable disease severity, recurrent pneumonia, and bronchiectasis. The outcome of COVID in patients with hypogammaglobulinemia is variable depending on age, comorbidities, type of immunodeficiency, and use of immunoglobulins. We report the favorable outcome of two family members diagnosed with\n                      <jats:italic toggle=\"yes\">DNAJC17<\/jats:italic>\n                      -related retinitis pigmentosa and hypogammaglobulinemia syndrome and infected with SARS-CoV-2 following contact with their mother who had COVID-19. We describe the different immune dysfunction in these patients and their impact on the course and management of SARS-CoV-2 infection.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/atm.atm_520_21","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T05:36:05Z","timestamp":1642052165000},"page":"66-69","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia"],"prefix":"10.4103","volume":"17","author":[{"given":"Abeer N.","family":"Alshukairi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasser A.","family":"Aldabbagh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najla M.","family":"Sayes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manal M.","family":"Al Gethamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed G.","family":"Alghamdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuhair A.","family":"Rahbeeni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashraf","family":"Dada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20240830","doi-asserted-by":"crossref","first-page":"180019","DOI":"10.1183\/16000617.0019-2018","article-title":"The broad spectrum of lung diseases in primary antibody deficiencies","volume":"27","author":"Cinetto","year":"2018","journal-title":"Eur Respir Rev"},{"key":"R2-9-20240830","doi-asserted-by":"crossref","first-page":"588013","DOI":"10.3389\/fmed.2021.588013","article-title":"Chronic diseases as a predictor for severity and mortality of COVID-19: A systematic review with cumulative meta-analysis","volume":"8","author":"Geng","year":"2021","journal-title":"Front Med (Lausanne"},{"key":"R3-9-20240830","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.jaip.2020.11.006","article-title":"COVID-19 infection in 10 common variable immunodeficiency patients in New York City","volume":"9","author":"Cohen","year":"2021","journal-title":"J Allergy Clin Immunol Pract"},{"key":"R4-9-20240830","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/j.jaci.2020.12.620","article-title":"UK PIN COVID-19 Consortium. COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience","volume":"147","author":"Shields","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"R5-9-20240830","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1097\/01.smj.0000203923.89986.58","article-title":"Retinitis pigmentosa and hypogammaglobulinemia","volume":"99","author":"Starr","year":"2006","journal-title":"South Med J"},{"key":"R6-9-20240830","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1038\/gim.2015.127","article-title":"Expanding the clinical, allelic, and locus heterogeneity of retinal dystrophies","volume":"18","author":"Patel","year":"2016","journal-title":"Genet Med"},{"key":"R7-9-20240830","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1182\/blood.2020008963","article-title":"COVID-19, plasma, and hypogammaglobulinemia","volume":"136","author":"Murphy","year":"2020","journal-title":"Blood"},{"key":"R8-9-20240830","doi-asserted-by":"crossref","first-page":"ofab335","DOI":"10.1093\/ofid\/ofab335","article-title":"Successful treatment of persistent coronavirus disease 2019 infection in a patient with hypogammaglobulinemia with REGN-COV2: A case report","volume":"8","author":"Luitel","year":"2021","journal-title":"Open Forum Infect Dis"},{"key":"R9-9-20240830","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1002\/iid3.450","article-title":"COVID-19 infection in CVID patients: What we know so far","volume":"9","author":"Weifenbach","year":"2021","journal-title":"Immun Inflamm Dis"},{"key":"R10-9-20240830","doi-asserted-by":"crossref","first-page":"eabc8511","DOI":"10.1126\/science.abc8511","article-title":"Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications","volume":"369","author":"Mathew","year":"2020","journal-title":"Science"},{"key":"R11-9-20240830","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1038\/s41591-021-01386-7","article-title":"CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer","volume":"27","author":"Bange","year":"2021","journal-title":"Nat Med"}],"container-title":["Annals of Thoracic Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/atm.atm_520_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:53:56Z","timestamp":1787756036000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/atm.atm_520_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/atm.atm_520_21","relation":{},"ISSN":["1817-1737"],"issn-type":[{"value":"1817-1737","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1]]}}}