{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:01:16Z","timestamp":1787169676870,"version":"build-2736575974"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Hanshia dabar<\/jats:italic>\n                      or\n                      <jats:italic toggle=\"yes\">hathkan<\/jats:italic>\n                      is one of the folklore plant of Odisha, the botanical source of which is\n                      <jats:italic toggle=\"yes\">Leea macrophylla<\/jats:italic>\n                      Roxb. ex Hornem., family Vitaceae. Its root and leaves are eaten as vegetables, and used for\n                      <jats:italic toggle=\"yes\">Rasayana<\/jats:italic>\n                      purpose (tonic and alterative properties).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>\n                      The aim is to assess the nutritive value and antioxidant potential of the root and leaves of\n                      <jats:italic toggle=\"yes\">L. macrophylla<\/jats:italic>\n                      with compound leaf.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods:<\/jats:title>\n                    <jats:p>\n                      Nutritional parameters such as energy value, carbohydrate, protein, true protein, fat, mineral contents, and Vitamin A, Vitamin C of the root and leaves of the plant were evaluated with standard procedures. The\n                      <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                      antioxidant properties of the root and leaf of\n                      <jats:italic toggle=\"yes\">L. macrophylla<\/jats:italic>\n                      were screened through 1,1diphenyl2picrylhydrazyl (DPPH) assay, the ferric reducing antioxidant power (FRAP) assay, and phosphomolybdenum assay.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Root is having higher energy value (391.87 Kcal\/100 g) as compared to leaf (353.62 Kcal\/100 g).\n                      <jats:italic toggle=\"yes\">L. macrophylla<\/jats:italic>\n                      root and leaf showed the presence of carbohydrates (30.65% and 21.72%), protein (8.78% and 9.37%), true protein (6.85% and 7.23%), fat (0.77% and 1.89%), iron (723.80 ppm and 285.07 ppm), zinc (26.51 ppm and 13.75 ppm), manganese (44.88 ppm and 35.00 ppm), phosphorous (0.07 ppm and 0.03 ppm), calcium (7806.90 ppm and 3862.80 ppm), Vitamin A (3.63 mg\/g and 2.47 mg\/g), and Vitamin C (8.49 mg\/g and 6.7 mg\/g), respectively. Percentage scavenging of DPPH radical was found to rise with an increase in concentration. IC50 values of root and leaf, by DPPH assay, were 66.46 and 110.68 \u03bcg\/ml, respectively. In the FRAP assay, the antioxidant activity of the methanolic extract of leaf (507.06 \u03bcmol\/l) was found to be more than root (455.93 \u03bcmol\/l). The total antioxidant capacity of root and leaf were 20.15 and 17.90 mg, equivalent to ascorbic acid on a dry weight basis, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Root and leaf of\n                      <jats:italic toggle=\"yes\">L. macrophylla<\/jats:italic>\n                      has the highest energy value, contains carbohydrate, protein, fat, iron, zinc, manganese, phosphorous, calcium, Vitamin A, and Vitamin C, and possesses antioxidant capacity.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ayu.ayu_88_19","type":"journal-article","created":{"date-parts":[[2023,3,26]],"date-time":"2023-03-26T04:53:39Z","timestamp":1679806419000},"page":"87-92","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of nutritional value and antioxidant activity of Leea macrophylla Roxb. ex Hornem. root and leaf"],"prefix":"10.4103","volume":"42","author":[{"given":"Sarvade Dattatray","family":"Durgadas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Acharya","family":"Rabinarayan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-4-20240901","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1136\/jcp.54.3.176","article-title":"Antioxidants in health and disease","volume":"54","author":"Young","year":"2001","journal-title":"J Clin Pathol"},{"key":"R3-4-20240901","doi-asserted-by":"crossref","first-page":"214","DOI":"10.5005\/jdras-10059-0054","article-title":"Pharmacognostical, DNA barcoding, and phytochemical analysis on leaves of Leea macrophylla Roxb. 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Daebong) seeds","volume":"45","author":"Akter","year":"2010","journal-title":"Int J Food Sci Technol"},{"key":"R23-4-20240901","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0076-6879(99)99005-5","article-title":"Ferric reducing\/antioxidant power assay: Direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration","volume":"299","author":"Benzie","year":"1999","journal-title":"Methods Enzymol"},{"key":"R24-4-20240901","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1006\/abio.1999.4019","article-title":"Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: Specific application to the determination of Vitamin E","volume":"269","author":"Prieto","year":"1999","journal-title":"Anal Biochem"},{"key":"R25-4-20240901","first-page":"327","article-title":"Nutrition in wound care management: A comprehensive overview","volume":"27","author":"Quain","year":"2015","journal-title":"Wounds"},{"key":"R26-4-20240901","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/j.1574-695X.2007.00331.x","article-title":"Biological activities of extracts from endophytic fungi isolated from Garcinia plants","volume":"51","author":"Phongpaichit","year":"2007","journal-title":"FEMS Immunol Med Microbiol"},{"key":"R27-4-20240901","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1006\/abio.1996.0292","article-title":"The ferric reducing ability of plasma (FRAP) as a measure of \u201cantioxidant power\u201d: The FRAP assay","volume":"239","author":"Benzie","year":"1996","journal-title":"Anal Biochem"},{"key":"R28-4-20240901","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/S0278-6915(99)00096-4","article-title":"Action of methanolic extract of mung bean hulls as inhibitors of lipid peroxidation and non-lipid oxidative damage","volume":"37","author":"Duh","year":"1999","journal-title":"Food Chem Toxicol"},{"key":"R29-4-20240901","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1016\/j.nutres.2003.08.005","article-title":"Antioxidant activities of peel, pulp and seed fractions as determined by FRAP assay","volume":"23","author":"Guo","year":"2003","journal-title":"Nutr Res"},{"key":"R30-4-20240901","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1021\/np9904509","article-title":"Flavonoids as antioxidants","volume":"63","author":"Pietta","year":"2000","journal-title":"J Nat Prod"},{"key":"R31-4-20240901","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1753-4887.1998.tb01670.x","article-title":"Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance","volume":"56","author":"Bravo","year":"1998","journal-title":"Nutr Rev"},{"key":"R32-4-20240901","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1146\/annurev.nutr.21.1.381","article-title":"Inhibition of carcinogenesis by dietary polyphenolic compounds","volume":"21","author":"Yang","year":"2001","journal-title":"Annu Rev Nutr"},{"key":"R33-4-20240901","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1749-6632.1998.tb09922.x","article-title":"The chemistry and biological effects of flavonoids and phenolic acids","volume":"854","author":"Croft","year":"1998","journal-title":"Ann N Y Acad Sci"},{"key":"R34-4-20240901","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1002\/(SICI)1097-0010(20000515)80:7<985::AID-JSFA572>3.0.CO;2-7","article-title":"Phenols in the plant and in man. 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