{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T16:17:53Z","timestamp":1788884273253,"version":"build-2803163510"},"reference-count":70,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      After the introduction of shunt treatment for the management of childhood hydrocephalus, a wide variety of complications related to this treatment modality have been recognized. The entity of slit ventricle syndrome (alternatively, symptomatic ventricular coaptation) is one of them, is frequently encountered in the pediatric population and its symptom complex resembles that of shunt failure. We conducted research on PubMed\n                      <jats:sup>\u00ae<\/jats:sup>\n                      , MEDLINE\n                      <jats:sup>\u00ae<\/jats:sup>\n                      , and Web of Science\n                      <jats:sup>\u00ae<\/jats:sup>\n                      , using the keywords: \u201cslit ventricles,\u201d \u201cslit ventricle syndrome,\u201d \u201cSVS\u201d and \u201cventricular coaptation.\u201d The aim of our review was to trace the advances made through the past decades, concerning our knowledge about the clinical characteristics, pathophysiology, and treatment options of this entity. The discrepancy among researchers about the offending etiology and the optimum treatment algorithm of this entity, as well as the necessity of an updated concept regarding shunt over drainage is analyzed. The multiple treatment modalities proposed and pathophysiologic mechanisms implicated for the treatment of slit ventricle syndrome illustrate the complexity of this entity. Consequently, the issue requires more detailed evaluation. In this review, we comment on all the main facets related to shunt over drainage and the resultant slit ventricle syndrome.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/bc.bc_29_21","type":"journal-article","created":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T14:54:43Z","timestamp":1629989683000},"page":"167-177","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":32,"title":["Slit ventricle syndrome"],"prefix":"10.4103","volume":"7","author":[{"given":"Dimitrios","family":"Panagopoulos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ploutarchos","family":"Karydakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marios","family":"Themistocleous","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20240830","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1159\/000083738","article-title":"The problematic slit ventricle syndrome. 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