{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:17:41Z","timestamp":1787761061789,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Polycythemia vera is a myeloproliferative disorder caused by clonal expansion of erythroid precursors in the bone marrow commonly due to a mutation in the Janus kinase 2 (JAK2) gene located in the short arm of chromosome 9. Hyperviscosity of blood due to high hematocrit causes a low flow state that may predispose to infarct. These commonly occur in the supratentorial compartment. The case of a 46-year-old man who had an isolated cerebellar infarct with high hematocrit and hemoglobin levels and low serum erythropoietin levels is described. Further investigations eventually led to the unmasking of a JAK2 mutation-negative polycythemia vera.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/bc.bc_37_22","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T01:30:50Z","timestamp":1670808650000},"page":"225-227","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Isolated cerebellar infarction in a case of JAK 2 mutation-negative polycythemia vera"],"prefix":"10.4103","volume":"8","author":[{"given":"Prasad","family":"Krishnan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20240830","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1161\/01.STR.21.8.1111","article-title":"Hematologic disorders and ischemic stroke. A selective review","volume":"21","author":"Hart","year":"1990","journal-title":"Stroke"},{"key":"R2-11-20240830","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s11864-018-0529-x","article-title":"Polycythemia vera","volume":"19","author":"Spivak","year":"2018","journal-title":"Curr Treat Options Oncol"},{"key":"R3-11-20240830","first-page":"2949","article-title":"Acute multiple cerebral infarction combined with cerebral microhemorrhage in polycythemia vera: A case report","volume":"18","author":"Wang","year":"2019","journal-title":"Exp Ther Med"},{"key":"R4-11-20240830","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1159\/000204688","article-title":"Isolated cerebellar infarction as a presenting symptom of polycythemia vera","volume":"88","author":"Hilzenrat","year":"1992","journal-title":"Acta Haematol"},{"key":"R5-11-20240830","first-page":"210","article-title":"Acute embolic cerebral ischemia as an initial presentation of polycythemia vera","volume":"6","author":"Chhatwani","year":"2016","journal-title":"NJMR"},{"key":"R6-11-20240830","doi-asserted-by":"crossref","first-page":"638","DOI":"10.12659\/AJCR.909322","article-title":"Ischemic stroke caused by secondary polycythemia and incidentally-found renal cell carcinoma: A case report","volume":"19","author":"Corse","year":"2018","journal-title":"Am J Case Rep"},{"key":"R7-11-20240830","doi-asserted-by":"crossref","first-page":"e231261","DOI":"10.1136\/bcr-2019-231261","article-title":"Acute ischaemic stroke in secondary polycythaemia due to complex congenital cyanotic heart disease","volume":"12","author":"Pandian","year":"2019","journal-title":"BMJ Case Rep"},{"key":"R8-11-20240830","doi-asserted-by":"crossref","first-page":"114","DOI":"10.4103\/0974-2727.72215","article-title":"JAK2 negative polycythemia vera","volume":"2","author":"Geetha","year":"2010","journal-title":"J Lab Physicians"},{"key":"R9-11-20240830","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1182\/blood-2016-03-643544","article-title":"The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia","volume":"127","author":"Arber","year":"2016","journal-title":"Blood"}],"container-title":["Brain Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/bc.bc_37_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:18:08Z","timestamp":1787757488000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/bc.bc_37_22"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/bc.bc_37_22","relation":{},"ISSN":["2394-8108"],"issn-type":[{"value":"2394-8108","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}