{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:06:18Z","timestamp":1787169978414,"version":"build-2736575974"},"reference-count":119,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Bacterial meningitis is a serious, life-threatening infection of the meninges. Several radiological studies highlight prominent structural alterations occurring in the cerebral vasculature, leading to significant cerebrovascular consequences during bacterial meningitis. Beginning with reflexive arterial vasospasm , cerebrovascular disease during bacterial meningitis proceeds through a orderly sequence of arterial vasculitis with inflammatory cell infiltration, medial smooth muscle migration and proliferation, medial necrosis, adventitial fibrosis and eventual intimal stenosis. As such, this review focuses on changes occurring within cerebral arteries during disease progression, highlighting the various structural modifications occurring in the arterial vessels that contribute to disturbances in cerebral hemodynamics and, ultimately, cerebrovascular consequences during bacterial meningitis.<\/jats:p>","DOI":"10.4103\/bc.bc_95_22","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T01:45:51Z","timestamp":1695692751000},"page":"135-147","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":12,"title":["Parainfectious cerebral vasculopathy complicating bacterial meningitis: Acute-short lived vasospasm followed by delayed-long lasting vasculitis"],"prefix":"10.4103","volume":"9","author":[{"given":"Vivig Shantha","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,9,27]]},"reference":[{"key":"R1-20240830","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1056\/NEJM198410043111409","article-title":"Bacterial meningitis: More involved than just the meninges","volume":"311","author":"Swartz","year":"1984","journal-title":"N Engl J Med"},{"key":"R2-20240830","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1212\/WNL.42.8.1497","article-title":"Cerebrovascular complications of bacterial meningitis in adults","volume":"42","author":"Pfister","year":"1992","journal-title":"Neurology"},{"key":"R3-20240830","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1001\/archneur.1984.04050170077022","article-title":"Cerebral arteritis and bacterial meningitis","volume":"41","author":"Igarashi","year":"1984","journal-title":"Arch Neurol"},{"key":"R4-20240830","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.0954-6820.1974.tb00994.x","article-title":"Regional cerebral blood flow, cerebral metabolic rate of oxygen, and cerebrospinal fluid acid-base variables in patients with acute meningitis and with acute encephalitis","volume":"196","author":"Paulson","year":"1974","journal-title":"Acta Med Scand"},{"key":"R5-20240830","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0022-3476(05)80683-3","article-title":"Cerebral blood flow and carbon dioxide reactivity in children with bacterial meningitis","volume":"117","author":"Ashwal","year":"1990","journal-title":"J Pediatr"},{"key":"R6-20240830","first-page":"943","article-title":"Evaluation of regional cerebral perfusion (rCBF) in acute neurological disorders in childhood","volume":"32","author":"Gordon","year":"1991","journal-title":"J Nucl Med"},{"key":"R7-20240830","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1212\/WNL.34.4.500","article-title":"Bacterial meningitis in infancy: Effects on intracranial pressure and cerebral blood flow velocity","volume":"34","author":"McMenamin","year":"1984","journal-title":"Neurology"},{"key":"R8-20240830","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1136\/jnnp.44.7.581","article-title":"Cerebral infarction in childhood bacterial meningitis","volume":"44","author":"Snyder","year":"1981","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"R9-20240830","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1001\/archneur.1980.00500520035004","article-title":"Cerebral computerized tomography in intracranial inflammatory disorders","volume":"37","author":"Weisberg","year":"1980","journal-title":"Arch Neurol"},{"key":"R10-20240830","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1097\/00004728-198212000-00003","article-title":"CT parenchymal abnormalities in bacterial meningitis: Clinical significance","volume":"6","author":"Packer","year":"1982","journal-title":"J Comput Assist Tomogr"},{"key":"R11-20240830","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1001\/archneur.1982.00510220048011","article-title":"Ischemic cerebrovascular complications of Haemophilus influenzae meningitis. 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