{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:42:06Z","timestamp":1786653726239,"version":"build-2736575974"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Beckwith\u2013Wiedemann syndrome (BWS) is a rare genetic disorder characterized by somatic overgrowth and an increased predisposition to various medical conditions, including neoplasms. This case report presents a 25-day-old male infant with BWS exhibiting macroglossia, hepatosplenomegaly, hyperinsulinemic hypoglycemia, gum hypertrophy, and cystic lesions in the maxillary arch, prompting a multidisciplinary collaboration of a pediatrician, pedodontist, oral surgeon, and an oral pathologist. The patient also presented with Hebling\u2019s Class III natal tooth. Following all the precautions, the natal tooth was extracted under local anesthesia. This case report stands out for documenting the presence of a natal tooth in a diagnosed case of BWS for the first time, contributing to the understanding of oral manifestations in rare genetic syndromes and underscoring the need for timely intervention and comprehensive medical care in managing this complex genetic syndrome.<\/jats:p>","DOI":"10.4103\/ccd.ccd_142_24","type":"journal-article","created":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T03:19:38Z","timestamp":1743218378000},"page":"56-60","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Diagnosis and Management of Natal Tooth Secondary to Beckwith\u2013Wiedemann Syndrome in a 25-day-old Infant: A Rare Case Report"],"prefix":"10.4103","volume":"16","author":[{"given":"G. Divya","family":"Lakshmi","sequence":"first","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, V. S. Dental College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. A.","family":"Amitha","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, V. S. Dental College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Suma","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, V. S. Dental College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. S.","family":"Priya","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, V. S. Dental College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,3,25]]},"reference":[{"key":"R1-20250327","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/ejhg.2009.106","article-title":"Beckwith-Wiedemann syndrome","volume":"18","author":"Weksberg","year":"2010","journal-title":"Eur J Hum Genet"},{"key":"R2-20250327","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/ajmg.c.30267","article-title":"Beckwith-Wiedemann syndrome","volume":"154C","author":"Choufani","year":"2010","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"R3-20250327","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.ejmg.2015.11.008","article-title":"Recommendations of the scientific committee of the Italian Beckwith-Wiedemann Syndrome association on the diagnosis, management and follow-up of the syndrome","volume":"59","author":"Mussa","year":"2016","journal-title":"Eur J Med Genet"},{"key":"R4-20250327","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.ejmg.2014.03.011","article-title":"Methylation analysis in tongue tissue of BWS patients identifies the (EPI) genetic cause in 3 patients with normal methylation levels in blood","volume":"57","author":"Alders","year":"2014","journal-title":"Eur J Med Genet"},{"key":"R5-20250327","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1542\/peds.112.1.191","article-title":"Controversies concerning Vitamin K and the newborn. 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