{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:59:30Z","timestamp":1790171970178,"version":"4.1.0"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Oral diseases affect over 3.5 billion people globally, with children in low- and middle-income countries disproportionately impacted. This study aimed to evaluate the effectiveness of an oral health curriculum in reducing dental caries increment and improving oral hygiene behavior among high school students in the Ernakulam district of Kerala, India.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cluster-randomized, parallel-group trial was conducted in six English-medium high schools in Ernakulam, Kerala, India, involving 1707 students aged 13\u201315 years. Schools were assigned to receive an oral health curriculum delivered either by a dental professional or a trained schoolteacher. The \u201cEverlasting Smiles\u201d curriculum was implemented over 24 months through six sessions with periodic reinforcement, covering key oral health topics. Outcomes assessed at baseline, 12, and 24 months included the primary outcome (decayed, missing, and filled teeth [DMFT]) and secondary outcomes (oral hygiene index simplified [OHI-S] and oral health-related knowledge, attitude, and behavior scores).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Significant improvements in oral health-related knowledge (mean: 8.03\u20138.76), attitude (2.77\u20133.23), and behavior (2.38\u20132.64) scores over 24 months (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), postintervention. Dental caries levels decreased, with DMFT reducing from 1.65 to 1.47 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.011) and DMFS from 2.01 to 1.81 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.018). Dentist-led interventions consistently showed greater improvements than teacher-led ones. Oral hygiene scores improved substantially, with OHI-S declining from 1.06 to 0.74 (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>A structured school-based oral health curriculum significantly reduces dental caries and improves oral hygiene behaviors. Integrating it into schools provides a scalable, cost-effective way to promote lifelong oral health and lasting public health benefits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number:<\/jats:title>\n                    <jats:p>Clinical Trial Registry of India (CTRI\/2022\/09\/045410), registered on September 12, 2022.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ccd.ccd_19_26","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T12:01:16Z","timestamp":1790078476000},"page":"174-186","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of an Oral Health Curriculum in Reducing Dental Caries Increment and Improving Oral Hygiene Behavior among Schoolchildren of Ernakulam District in Kerala, India: A Cluster-randomized Trial"],"prefix":"10.4103","volume":"17","author":[{"given":"Hindol","family":"Das","sequence":"first","affiliation":[{"name":"Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"},{"name":"Population Oral Health, School of Dentistry, The University of Sydney, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandrashekar","family":"Janakiram","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Vijay","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Gutjahr","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Research, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra Chaithanyam","family":"Bijukumar","sequence":"additional","affiliation":[{"name":"Department of Mathematics, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vineetha","family":"Karuveettil","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkitachalam","family":"Ramanarayanan","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parvathy","family":"Balachandran","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balagopal","family":"Varma","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,22]]},"reference":[{"key":"R1-20260923","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1177\/003335491012500202","article-title":"Oral health: The silent epidemic","volume":"125","author":"Benjamin","year":"2010","journal-title":"Public Health Rep"},{"key":"R4-20260923","first-page":"6637196","article-title":"Prevalence of Dental Caries and Its Associated Factors among Primary School Children in Ethiopia","author":"Shitie","year":"2021","journal-title":"Int J Dent 2021"},{"key":"R5-20260923","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.2105\/AJPH.2011.300478","article-title":"The impact of oral health on the academic performance of disadvantaged children","volume":"102","author":"Seirawan","year":"2012","journal-title":"Am J Public Health"},{"key":"R6-20260923","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.2105\/AJPH.2010.200915","article-title":"Impact of poor oral health on children's school attendance and performance","volume":"101","author":"Jackson","year":"2011","journal-title":"Am J Public Health"},{"key":"R7-20260923","doi-asserted-by":"crossref","first-page":"e082922","DOI":"10.1136\/bmjopen-2023-082922","article-title":"Dental caries prevalence and caries-associated risk factors of students aged 12-15 in Xide County of Liangshan Prefecture, China: A cross-sectional study","volume":"14","author":"Sun","year":"2024","journal-title":"BMJ Open"},{"key":"R9-20260923","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.jpeds.2019.01.045","article-title":"Children's oral health and academic performance: Evidence of a Persisting relationship over the last decade in the United States","volume":"209","author":"Guarnizo-Herre\u00f1o","year":"2019","journal-title":"J Pediatr"},{"key":"R11-20260923","doi-asserted-by":"crossref","first-page":"316","DOI":"10.34172\/hpp.2020.50","article-title":"School as ideal setting to promote health and wellbeing among young people","volume":"10","author":"Pulimeno","year":"2020","journal-title":"Health Promot Perspect"},{"key":"R13-20260923","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1080\/10888691.2018.1537791","article-title":"Implications for educational practice of the science of learning and development","volume":"24","author":"Darling-Hammond","year":"2020","journal-title":"Appl Dev Sci"},{"key":"R14-20260923","first-page":"43","article-title":"Integration of oral health interventions in the health promoting schools program in Iran: A multi-stakeholder feasibility assessment","volume":"18","author":"Beigi","year":"2021","journal-title":"Front Dent"},{"key":"R17-20260923","first-page":"677","article-title":"Health-promoting schools: An opportunity for oral health promotion","volume":"83","author":"Kwan","year":"2005","journal-title":"Bull World Health Organ"},{"key":"R20-20260923","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4103\/0970-4388.31983","article-title":"Status of oral health awareness in Indian children as compared to Western children: A thought provoking situation (a pilot study)","volume":"25","author":"Grewal","year":"2007","journal-title":"J Indian Soc Pedod Prev Dent"},{"key":"R21-20260923","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1016\/j.identj.2023.07.634","article-title":"Oral health curriculum to reduce dental caries increment in schoolchildren","volume":"73","author":"Das","year":"2023","journal-title":"Int Dent J"},{"key":"R22-20260923","doi-asserted-by":"crossref","first-page":"277","DOI":"10.4103\/jehp.jehp_436_21","article-title":"A model for implementing oral health-promoting school: Integration with dental students' educational curriculum: A protocol study","volume":"11","author":"Tahani","year":"2022","journal-title":"J Educ Health Promot"},{"key":"R23-20260923","doi-asserted-by":"crossref","first-page":"e069877","DOI":"10.1136\/bmjopen-2022-069877","article-title":"Effectiveness of an oral health curriculum in reducing dental caries increment and improving oral hygiene behaviour among schoolchildren of Ernakulam district in Kerala, India: Study protocol for a cluster randomised trial","volume":"13","author":"Das","year":"2023","journal-title":"BMJ Open"},{"key":"R24-20260923","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1159\/000452275","article-title":"the impact of integrating oral health education into a medical curriculum","volume":"26","author":"Park","year":"2017","journal-title":"Med Princ Pract"},{"key":"R25-20260923","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1097\/JPA.0000000000000024","article-title":"Adoption of oral health curriculum by physician assistant education programs in 2014","volume":"26","author":"Langelier","year":"2015","journal-title":"J Physician Assist Educ"},{"key":"R26-20260923","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/01367895-201324030-00005","article-title":"Advancing oral health in physician assistant education: Evaluation of an innovative interprofessional oral health curriculum","volume":"24","author":"Bowser","year":"2013","journal-title":"J Physician Assist Educ"},{"key":"R27-20260923","doi-asserted-by":"crossref","first-page":"775","DOI":"10.22454\/FamMed.2018.435186","article-title":"Advancing oral health knowledge and attitudes of physician assistant students using the smiles for life oral health curriculum","volume":"50","author":"Forbes","year":"2018","journal-title":"Fam Med"},{"key":"R28-20260923","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.acap.2012.10.010","article-title":"Evaluation of a national bright futures oral health curriculum for pediatric residents","volume":"13","author":"Bernstein","year":"2013","journal-title":"Acad Pediatr"},{"key":"R30-20260923","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1097\/00001888-200505000-00004","article-title":"An oral health curriculum for medical students at the University of Washington","volume":"80","author":"Mouradian","year":"2005","journal-title":"Acad Med"},{"key":"R31-20260923","doi-asserted-by":"crossref","first-page":"90","DOI":"10.4103\/jehp.jehp_619_19","article-title":"Effectiveness of a curriculum-based educational intervention on oral health behavior and dental caries experience among Indian schoolchildren","volume":"9","author":"Karuveettil","year":"2020","journal-title":"J Educ Health Promot"},{"key":"R34-20260923","doi-asserted-by":"crossref","first-page":"S409","DOI":"10.1016\/j.identj.2024.07.1255","article-title":"Effectiveness of school-based oral health education interventions among schoolchildren","volume":"74","author":"Das","year":"2024","journal-title":"Int Dent J"},{"key":"R35-20260923","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/s41432-024-01101-8","article-title":"Effectiveness of school-based oral health education interventions on oral health status and oral hygiene behaviors among schoolchildren: An umbrella review","volume":"26","author":"Das","year":"2025","journal-title":"Evid Based Dent"},{"key":"R37-20260923","doi-asserted-by":"crossref","first-page":"216","DOI":"10.4103\/0970-4388.85825","article-title":"The most effective and essential way of improving the oral health status education","volume":"29","author":"Chachra","year":"2011","journal-title":"J Indian Soc Pedod Prev Dent"},{"key":"R38-20260923","doi-asserted-by":"crossref","first-page":"184","DOI":"10.4103\/2230-8229.102319","article-title":"The use of school teachers to promote oral hygiene in some secondary school students at Hyderabad, Andhra Pradesh, India: A short term prospective pilot study","volume":"19","author":"Chandrashekar","year":"2012","journal-title":"J Family Community Med"},{"key":"R39-20260923","doi-asserted-by":"crossref","first-page":"406","DOI":"10.3390\/healthcare10020406","article-title":"Oral hygiene practices and oral health knowledge among students in Split, Croatia","volume":"10","author":"Tadin","year":"2022","journal-title":"Healthcare (Basel)"},{"key":"R40-20260923","first-page":"E614","article-title":"Oral health knowledge, attitudes and practice in 12-year-old schoolchildren","volume":"12","author":"Smyth","year":"2007","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"R41-20260923","first-page":"500","article-title":"Educational intervention of improve student's oral health: A systematic review and meta-analysis school-based","volume":"52","author":"Dadipoor","year":"2023","journal-title":"Iran J Public Health"},{"key":"R43-20260923","doi-asserted-by":"crossref","first-page":"e0256007","DOI":"10.1371\/journal.pone.0256007","article-title":"Effectiveness of the school-based oral health promotion programmes from preschool to high school: A systematic review","volume":"16","author":"Bramantoro","year":"2021","journal-title":"PLoS One"},{"key":"R44-20260923","doi-asserted-by":"crossref","first-page":"338","DOI":"10.5005\/jp-journals-10005-2395","article-title":"Effectiveness of oral health educational methods among school children aged 5-16 years in improving their oral health status: A meta-analysis","volume":"15","author":"Gurav","year":"2022","journal-title":"Int J Clin Pediatr Dent"},{"key":"R45-20260923","doi-asserted-by":"crossref","first-page":"1428638","DOI":"10.3389\/froh.2024.1428638","article-title":"Cost-effectiveness analysis design for interventions to prevent children's oral disease","volume":"5","author":"Spetz","year":"2024","journal-title":"Front Oral Health"},{"key":"R46-20260923","doi-asserted-by":"crossref","first-page":"e0293761","DOI":"10.1371\/journal.pone.0293761","article-title":"Perceptions of oral health promotion in primary schools among health and education officials, community leaders, policy makers, teachers, and parents in Gulu district, Northern Uganda: A qualitative study","volume":"18","author":"Akera","year":"2023","journal-title":"PLoS One"},{"key":"R47-20260923","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1111\/josh.13450","article-title":"Oral health for all schools: A call to integrate oral health in school systems","volume":"94","author":"Wordley","year":"2024","journal-title":"J Sch Health"}],"container-title":["Contemporary Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_19_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:01:13Z","timestamp":1790168473000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_19_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ccd.ccd_19_26","relation":{},"ISSN":["0976-237X","0976-2361"],"issn-type":[{"value":"0976-237X","type":"print"},{"value":"0976-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-01-13","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-17","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}