{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:59:36Z","timestamp":1790171976493,"version":"4.1.0"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Calcifying odontogenic cyst (COC), commonly termed the Gorlin cyst, is a developmental odontogenic cyst characterized by \u201cghost cells\u201d within its epithelial lining. The World Health Organization classifies it as a benign cystic entity with distinctive histopathological features. Although it constitutes approximately 1%\u20132% of odontogenic cysts and tumors, its diverse clinicopathological spectrum may complicate diagnosis. We present an unusual case of COC with clear cell changes in a 48-year-old female presenting with pain and swelling in the left posterior mandible. Radiographic evaluation revealed a well-demarcated multilocular radiolucency containing radiopaque foci. Histopathological examination demonstrated cystic spaces lined by palisaded columnar epithelium with stellate reticulum-like areas, numerous ghost cells, and focal clear cell changes. Recognition of this unusual variant is critical for accurate diagnosis and appropriate clinical management.<\/jats:p>","DOI":"10.4103\/ccd.ccd_251_26","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T12:01:18Z","timestamp":1790078478000},"page":"215-220","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Calcifying Odontogenic Cyst Exhibiting Focal Clear Cell Change: A Diagnostic Challenge"],"prefix":"10.4103","volume":"17","author":[{"given":"Keya","family":"Sarkar","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudeshna","family":"Bagchi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. K. Abdul","family":"Mahmud","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudra Prasad","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeet Kumar","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mousumi","family":"Pal","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,9,22]]},"reference":[{"key":"R3-20260923","doi-asserted-by":"crossref","first-page":"192","DOI":"10.5306\/wjco.v10.i4.192","article-title":"Dentinogenic ghost cell tumor: A case report","volume":"10","author":"Patankar","year":"2019","journal-title":"World J Clin Oncol"},{"key":"R4-20260923","doi-asserted-by":"crossref","first-page":"98","DOI":"10.4103\/JMAU.JMAU_32_20","article-title":"Calcifying epithelial odontogenic cyst of maxilla: Report of a case and review and discussion on the terminology and classification","volume":"9","author":"Chandran","year":"2021","journal-title":"J Microsc Ultrastruct"},{"key":"R5-20260923","doi-asserted-by":"crossref","first-page":"20200586","DOI":"10.1259\/dmfr.20200586","article-title":"Calcifying odontogenic cysts: A 20-year retrospective clinical and radiological review","volume":"50","author":"Nel","year":"2021","journal-title":"Dentomaxillofac Radiol"},{"key":"R6-20260923","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1051\/mbcb\/2019023","article-title":"Calcifying odontogenic cyst: A report of two clinical cases","volume":"25","author":"Lagarde","year":"2019","journal-title":"J Oral Med Oral Surg"},{"key":"R7-20260923","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/0030-4220(85)90265-8","article-title":"Clear cell change in a calcifying odontogenic cyst","volume":"60","author":"Ng","year":"1985","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"R9-20260923","first-page":"168","article-title":"The World Health Organization classification of odontogenic lesions: A summary of the changes of the 2022 (5th) edition","volume":"38","author":"Soluk-Tekkesin","year":"2022","journal-title":"Turk J Pathol"},{"key":"R10-20260923","doi-asserted-by":"crossref","first-page":"100484","DOI":"10.1016\/j.modpat.2024.100484","article-title":"Calcifying odontogenic cyst demonstrates recurrent WNT pathway mutations and so-called adenoid ameloblastoma-like histology: Evidence supporting its classification as a neoplasm","volume":"37","author":"Oh","year":"2024","journal-title":"Mod Pathol"}],"container-title":["Contemporary Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_251_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:02:20Z","timestamp":1790168540000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_251_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ccd.ccd_251_26","relation":{},"ISSN":["0976-237X","0976-2361"],"issn-type":[{"value":"0976-237X","type":"print"},{"value":"0976-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-04-27","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-15","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}