{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:21:49Z","timestamp":1787764909524,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"Abstract<\/jats:title>\n \n Neuropathologic chewing is an involuntary chewing reflex characterized by repetitive, forceful jaw movements, often leading to self-inflicted oral trauma. This case report aims to describe the dental management of a 13-year-old male with\n GNAO1<\/jats:italic>\n -associated disorder presenting with severe neuropathologic chewing and resulting oral trauma. A novel, custom-designed three-dimensional (3D)-printed intraoral appliance was fabricated to protect the oral tissues. The appliance prevented further self-inflicted injury and supported tissue healing, significantly improving the patient\u2019s quality of life. This case highlights the role of personalized dental intervention in managing neuropathologic chewing. It emphasizes the potential of 3D printing as an innovative and effective solution for complex neurogenetic disorders and underscores the importance of interdisciplinary care in pediatric dental management.\n <\/jats:p>","DOI":"10.4103\/ccd.ccd_337_25","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T15:00:10Z","timestamp":1781535610000},"page":"118-121","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Innovative Three-dimensional-printed Appliance for the Management of Neuropathologic Chewing in a Child"],"prefix":"10.4103","volume":"17","author":[{"given":"Janaki","family":"Shaji","sequence":"first","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R Balagopal","family":"Varma","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. K. Sapna","family":"Varma","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eldo","family":"Babu","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"R1-20260803","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/0022-3913(78)90038-0","article-title":"The use of tongue-depressing stents for neuropathologic chewing","volume":"40","author":"Jackson","year":"1978","journal-title":"J Prosthet Dent"},{"key":"R2-20260803","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/j.1754-4505.1994.tb01102.x","article-title":"Neuropathological chewing: A dental management protocol and treatment appliances for pediatric patients","volume":"14","author":"Hallett","year":"1994","journal-title":"Spec Care Dentist"},{"key":"R4-20260803","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/0030-4220(84)90151-8","article-title":"Prevention of self-inflicted trauma in comatose patients","volume":"57","author":"Peters","year":"1984","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"R5-20260803","first-page":"334","article-title":"Neuropathologic chewing in comatosed children: A case report","volume":"3","author":"Freedman","year":"1981","journal-title":"Pediatr Dent"},{"key":"R6-20260803","doi-asserted-by":"crossref","first-page":"9249","DOI":"10.3390\/ijerph18179249","article-title":"A digital fabrication of dental prosthesis for preventing self-injurious behavior related to autism spectrum disorder: A case report","volume":"18","author":"Hong","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"R7-20260803","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3390\/reports1010008","article-title":"Management and prevention of oral self-injuries in Lesch-Nyhan syndrome","volume":"1","author":"Caserta","year":"2018","journal-title":"Reports"},{"key":"R8-20260803","article-title":"Neuro Bite Shield","author":"Varma"}],"container-title":["Contemporary Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_337_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:50:11Z","timestamp":1787763011000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_337_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ccd.ccd_337_25","relation":{},"ISSN":["0976-237X","0976-2361"],"issn-type":[{"value":"0976-237X","type":"print"},{"value":"0976-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-06-26","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-07","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}