{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:31:56Z","timestamp":1786649516454,"version":"build-2736575974"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Preventive dental procedures are cornerstones of caries management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>This research aims to analyze the clinical effectiveness of pit and fissure sealants when applied to etched enamel pretreated with solvents compared to the conventional etch and seal technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods:<\/jats:title>\n                    <jats:p>Children and adolescents with clinically healthy occlusal surfaces or noncavitated occlusal carious lesions on permanent first and\/or second molars in all four quadrants were randomly allocated into four groups. A total population of 87 participants (348 teeth) were selected for the research based on the inclusion criteria. Following the enrollment, teeth were etched and sequentially assigned for application of Group 1 = Conventional Etch Seal (control group), Group 2 = isopropyl alcohol (IPA), Group 3 = acetone, and Group 4 = ethanol before sealant application. All participants were evaluated for marginal integrity, discoloration, and clinical retention of pit and fissure sealant after 6-month intervals and 12-month intervals using Feigal\u2019s criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At 6-month and 12-month intervals, the collected data were compiled and statistically analyzed using the Chi-square test of significance for marginal integrity between groups all four groups. The Wilcoxon rank test was assigned to assess the difference between parameters measured at 6 months and 12 months. A highly significant difference was found between the groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) for marginal integrity and anatomic form at 6 months and 12 months when intergroup comparison was done using the Kruskal\u2013Wallis test.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Surfactants such as IPA and acetone can be adopted while choosing methods for the long-term clinical success of resin-based sealants for increasing wettability and penetration depth.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ccd.ccd_338_23","type":"journal-article","created":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T05:00:07Z","timestamp":1735016407000},"page":"225-231","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Effectiveness of Pit and Fissure Sealants Using Solvents for Improving Surface Wettability of Enamel: A Randomized Controlled Trial"],"prefix":"10.4103","volume":"15","author":[{"given":"Anshula N","family":"Deshpande","sequence":"first","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth (Deemed to be University), Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooja V","family":"Bane","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth (Deemed to be University), Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simron","family":"Baishya","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth (Deemed to be University), Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yash","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth (Deemed to be University), Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sneha","family":"Dori","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth (Deemed to be University), Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,12,24]]},"reference":[{"key":"R1-20241224","first-page":"1","article-title":"Dental caries and sealant prevalence in children and adolescents in the United States, 2011-2012","author":"Dye","year":"2015","journal-title":"NCHS Data Brief"},{"key":"R2-20241224","first-page":"282","article-title":"Sealants for preventing and arresting pit-and-fissure occlusal caries in primary and permanent molars","volume":"38","author":"Wright","year":"2016","journal-title":"Pediatr Dent"},{"key":"R3-20241224","doi-asserted-by":"crossref","first-page":"e60","DOI":"10.1016\/j.dental.2010.11.010","article-title":"Evaluation of the integrity of dental sealants by optical coherence tomography","volume":"27","author":"Braz","year":"2011","journal-title":"Dent 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Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_338_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:54:55Z","timestamp":1786647295000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_338_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ccd.ccd_338_23","relation":{},"ISSN":["0976-237X","0976-2361"],"issn-type":[{"value":"0976-237X","type":"print"},{"value":"0976-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"2023-07-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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