{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:32:24Z","timestamp":1787758344341,"version":"build-2784847793"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Context:<\/jats:title>\n                    <jats:p>The changes in the volume and dimensions of the alveolar bone after tooth extraction often lead to challenges in prosthetic rehabilitation of the same necessitating ridge preservation procedures (RPP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The aim of this randomized clinical trial was to evaluate and compare the dimensional and histomorphometric changes of the sites preserved using the collagen membrane with and without demineralized bone matrix (DMBM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Settings and Design:<\/jats:title>\n                    <jats:p>Interventional, parallel-design, double blinded, randomized controlled trail.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A randomized controlled trial was designed with 45 participants having at least 2 teeth indicated for were enrolled in this study. The sites were randomly assigned to the control group (RPP using collagen membrane) and the test group (RPP using collagen membrane with DMBM). The clinical parameters assessed were alveolar bone width and alveolar bone height. Histomorphometric analysis was carried out on tissue trephined from the preserved sites to evaluate the percentage of bone and connective tissue (CT %) formed 8 months postRPP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Analysis Used:<\/jats:title>\n                    <jats:p>\n                      Shapiro \u2212 Wilk test and paired and unpaired\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Horizontal resorption was significantly less in the test group (7.375 \u00b1 1.64). Histomorphometry of these sites revealed a complete absence of residual graft particles, presence of trabecular bone, and a more mineralized matrix (63.256%) as compared to the control sites (46.833%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The use of DMBM along with the collagen membrane for RPP yielded better results both clinically and histomorphometically.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ccd.ccd_347_21","type":"journal-article","created":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T13:32:35Z","timestamp":1667827955000},"page":"375-382","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Histomorphometric Analysis of Residual Alveolar Ridge Preserved using Collagen Cell Occlusive Membrane Alone and Along with Demineralized Bone Matrix Following Tooth Extraction"],"prefix":"10.4103","volume":"13","author":[{"given":"Subash Chandra","family":"Raj","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiba Shankar","family":"Pradhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annuroopa","family":"Mahapatra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelima","family":"Katti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devapratim","family":"Mohanty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachna","family":"Rath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaushik","family":"Patnaik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poonam","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20240901","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.5037\/jomr.2019.10305","article-title":"Extraction socket preservation with or without membranes, soft tissue influence on post extraction alveolar ridge preservation: A systematic review","volume":"10","author":"Faria-Almeida","year":"2019","journal-title":"J Oral Maxillofac Res"},{"key":"R2-13-20240901","first-page":"646","article-title":"Socket preservation as a precursor of future implant placement: Review of the literature and case reports","volume":"28","author":"John","year":"2007","journal-title":"Compend Contin Educ Dent"},{"key":"R3-13-20240901","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1097\/SCS.0000000000000887","article-title":"Alveolar ridge preservation with deproteinized bovine bone graft and collagen membrane and delayed implants","volume":"25","author":"Pang","year":"2014","journal-title":"J Craniofac Surg"},{"key":"R4-13-20240901","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1111\/j.1600-0501.2011.02288.x","article-title":"Clinical, histologic and histomorphometric evaluation of socket preservation using a synthetic nanocrystalline hydroxyapatite in comparison with a bovine xenograft: A randomized clinical trial","volume":"23","author":"Gholami","year":"2012","journal-title":"Clin Oral Implants Res"},{"key":"R5-13-20240901","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1902\/jop.2000.71.6.1015","article-title":"Porous bovine bone mineral in healing of human extraction sockets. 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