{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:33:08Z","timestamp":1792801988971,"version":"4.5.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Chronic renal disease (CRD) is a progressive, irreversible loss of renal mass and function, posing a significant health concern. Secondary hyperparathyroidism caused by hypokalcemia in CRD often leads to renal osteodystrophy (ROD), a bone pathology resulting from alterations in mineral metabolism. ROD typically occurs early in renal failure and progresses as kidney function deteriorates. Marked jaw enlargement remains a rare but severe complication of the ROD, causing significant facial disfigurement. This case series highlights the four cases of ROD with extensive orofacial involvement, emphasizing the importance of early diagnosis and management.<\/jats:p>","DOI":"10.4103\/ccd.ccd_353_25","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T15:00:15Z","timestamp":1781535615000},"page":"147-151","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["\u201cThe Renal Trail Reveals Masked Face\u201d \u2013 A Unique Case Series"],"prefix":"10.4103","volume":"17","author":[{"given":"S.","family":"Nivetha","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government Dental College, Kerala University of Health Sciences, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Tinky","family":"Bose","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government Dental College, Kerala University of Health Sciences, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. M.","family":"Mini","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government Dental College, Kerala University of Health Sciences, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. A","family":"Chinnu","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government Dental College, Kerala University of Health Sciences, Thiruvananthapuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"R1-20260803","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s10006-015-0490-9","article-title":"Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease","volume":"19","author":"Lopes","year":"2015","journal-title":"Oral Maxillofac Surg"},{"key":"R2-20260803","doi-asserted-by":"crossref","first-page":"13","DOI":"10.9734\/ijmpcr\/2024\/v17i2368","article-title":"Case report on brown tumor: An unusual expression of renal osteodystrophy and secondary hyperparathyroidism","volume":"17","author":"Krishna","year":"2024","journal-title":"Int J Med Pharm Case Rep"},{"key":"R3-20260803","article-title":"A case study of renal osteodystrophy: Challenges of management","volume":"2","author":"Ali","year":"2016","journal-title":"Iraqi J Med Sci"},{"key":"R4-20260803","doi-asserted-by":"crossref","first-page":"e44342","DOI":"10.1097\/MD.0000000000044342","article-title":"Apresentation of brown tumor in a patient with parathyroid adenoma and end-stage renal disease: A case report","volume":"104","author":"Gohar","year":"2025","journal-title":"Medicine (Baltimore)"},{"key":"R5-20260803","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.radcr.2021.11.061","article-title":"Uremic leontiasis ossea: Distinctive imaging features allow differentiation from other clinical causes of leontiasis ossea","volume":"17","author":"Alamer","year":"2022","journal-title":"Radiol Case Rep"},{"key":"R6-20260803","doi-asserted-by":"crossref","first-page":"27","DOI":"10.25259\/JCIS_18_2021","article-title":"Uremic leontiasis ossea","volume":"11","author":"Heard","year":"2021","journal-title":"J Clin Imaging Sci"},{"key":"R7-20260803","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.cden.2021.02.006","article-title":"Radiographic diagnosis of systemic diseases manifested in jaws","volume":"65","author":"Ko","year":"2021","journal-title":"Dent Clin North Am"},{"key":"R8-20260803","doi-asserted-by":"crossref","first-page":"2593710","DOI":"10.1080\/0886022X.2025.2593710","article-title":"Advances in noninvasive diagnosis of renal osteodystrophy","volume":"47","author":"Yang","year":"2025","journal-title":"Ren Fail"},{"key":"R9-20260803","doi-asserted-by":"crossref","first-page":"316","DOI":"10.5327\/2525-5711.316","article-title":"Renal osteodystrophy in the oral and maxillofacial region: A case report and literature review","volume":"10","author":"Demenech","year":"2025","journal-title":"J Oral Diagn"},{"key":"R10-20260803","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1111\/1744-9987.14177","article-title":"Current therapeutic approach of chronic kidney disease-mineral and bone disorder","volume":"28","author":"Zaimi","year":"2024","journal-title":"Ther Apher Dial"},{"key":"R11-20260803","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1097\/MNH.0000000000000918","article-title":"Renal osteodystrophy: Something old, something new, something needed","volume":"32","author":"David","year":"2023","journal-title":"Curr Opin Nephrol Hypertens"}],"container-title":["Contemporary Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_353_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:50:12Z","timestamp":1787763012000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_353_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ccd.ccd_353_25","relation":{},"ISSN":["0976-237X","0976-2361"],"issn-type":[{"value":"0976-237X","type":"print"},{"value":"0976-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-07-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}