{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:34:57Z","timestamp":1786649697288,"version":"build-2736575974"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>Periodontal plastic surgery is constantly seeking alternatives that can replace the use of connective tissue grafts, due to the need for a second surgical area and the possibility of reducing the morbidity of the procedure and providing better comfort to the patient. The use of leukocyte- and platelet-rich fibrin (L-PRF) in the treatment of gingival recessions (GRs) has been studied and its potential has been observed. We report a clinical case of a 49-year-old female patient, a non-smoker, with hypothyroidism and multiple gingival recessions (GRs) in the anterior teeth classified as Miller Class I or Cairo Type 1 (RT1-), which are not associated with a non-carious cervical lesion. The patient presented with aesthetic discomfort and dentin hypersensitivity. Root coverage of the recessions was performed with L-PRF membranes associated with a coronally advanced flap. After 8 months of follow-up, we observed complete coverage of the exposed roots, thickness keratinized gingiva gain, and patient satisfaction with gingival esthetics and dentin hypersensitivity.<\/jats:p>","DOI":"10.4103\/ccd.ccd_384_25","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T09:00:08Z","timestamp":1766739608000},"page":"272-275","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Root Coverage of Multiple Gingival Recessions using Leukocyte- and Platelet-rich Fibrin Associated with Coronally Advanced Flap"],"prefix":"10.4103","volume":"16","author":[{"given":"Thaissa Cavalcante Vieira","family":"Bitu","sequence":"first","affiliation":[{"name":"Department of Dentistry, Christus University Center, Fortaleza, Ceara, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natacha Malu Miranda","family":"Da Costa","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael Linard","family":"Avelar","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Christus University Center, Fortaleza, Ceara, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uislen Berian","family":"Cadore","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9rgio Lu\u00eds Scombatti","family":"Souza","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1tila Vin\u00edcius Vitor","family":"Nobre","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Christus University Center, Fortaleza, Ceara, Brazil"},{"name":"Department of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"R1-20251226","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1002\/JPER.22-0501","article-title":"Diagnostic reproducibility of the 2018 classification of gingival recession defects and gingival phenotype: A multicenter inter- and intra-examiner agreement study","volume":"94","author":"Pini","year":"2023","journal-title":"J Periodontol"},{"key":"R2-20251226","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s00784-024-05694-3","article-title":"Treatment of multiple adjacent gingival recessions using leucocyte- and platelet-rich fibrin with coronally advanced flap: A 12-month split-mouth controlled randomized clinical trial","volume":"28","author":"Yavuz","year":"2024","journal-title":"Clin Oral Investig"},{"key":"R3-20251226","doi-asserted-by":"crossref","first-page":"144","DOI":"10.3390\/medicina57020144","article-title":"Platelet-rich fibrin in single and multiple coronally advanced flap for type 1 recession: An Updated systematic review and meta-analysis","volume":"57","author":"Mancini","year":"2021","journal-title":"Medicina (Kaunas)"},{"key":"R4-20251226","doi-asserted-by":"crossref","first-page":"e20170278","DOI":"10.1590\/1678-7757-2017-0278","article-title":"Evaluation of the effect of dose-dependent platelet-rich fibrin membrane on treatment of gingival recession: A randomized, controlled clinical trial","volume":"26","author":"Culhaoglu","year":"2018","journal-title":"J Appl Oral Sci"},{"key":"R5-20251226","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1902\/jop.2015.150420","article-title":"Use of platelet-rich fibrin membrane in the treatment of gingival recession: A systematic review and meta-analysis","volume":"87","author":"Moraschini","year":"2016","journal-title":"J Periodontol"},{"key":"R6-20251226","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1007\/s00784-013-1170-5","article-title":"Platelet-rich fibrin in the treatment of localized gingival recessions: A split-mouth randomized clinical trial","volume":"18","author":"Eren","year":"2014","journal-title":"Clin Oral Investig"},{"key":"R7-20251226","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/jcpe.12643","article-title":"Regenerative potential of leucocyte- and platelet-rich fibrin. Part A: Intra-bony defects, furcation defects and periodontal plastic surgery. 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