{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:22:35Z","timestamp":1787772155575,"version":"build-2784847793"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"Abstract<\/jats:title>\n \n Introduction:<\/jats:title>\n Silver diamine fluoride (SDF) is a topical treatment for carious lesions and a primary preventative for newly exposed high-risk surfaces such as fissures and roots in the first molars. Using potassium iodide (KI) after applying SDF has been recommended as a way of reducing the severity of black staining, as well as preserving its antibacterial effect useful in deep caries.<\/jats:p>\n <\/jats:sec>\n \n Objective:<\/jats:title>\n \n The objective of this research was to compare the antibacterial effect of SDF, with and without KI, on\n Streptococcus mutans<\/jats:italic>\n (\n S<\/jats:italic>\n .\n mutans<\/jats:italic>\n ) and dental biofilm.\n <\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n The antibacterial effects of SDF, KI, and the combination of both were measured using three different techniques (inhibition halo, minimum inhibitory effect [MIE], and colony-forming unit [CFU], testing).<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The results were then subjected to statistical analysis. Analyzed by means of the Kruskal\u2013Wallis statistical test, the inhibition halos yielded a value of\n P<\/jats:italic>\n = 0.3309. Using the MIE test, only the SDF treatment produced an antibacterial effect, at 10%, compared to the KI group, with\n P<\/jats:italic>\n = 0.001. Finally, the CFU test revealed a total absence of colonies for all three reagents. All three substances analyzed achieved total inhibition of\n S<\/jats:italic>\n .\n mutans<\/jats:italic>\n . SDF is effective even in its minimal commercial concentration. Its antibacterial capacity decreases with the addition of KI.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n \n The three substances analyzed at their maximum concentrations exhibited an antibacterial effect against\n S<\/jats:italic>\n .\n mutans<\/jats:italic>\n , resulting in total inhibition.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ccd.ccd_393_23","type":"journal-article","created":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T06:00:32Z","timestamp":1711173632000},"page":"22-26","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Antibacterial Effects of Silver Diamine Fluoride with and without Potassium Iodide against Streptococcus mutans"],"prefix":"10.4103","volume":"15","author":[{"given":"Carlos Alonso","family":"Alvarez-Mar\u00edn","sequence":"first","affiliation":[{"name":"The Advanced Studies and Research Center in Dentistry Dr. Keisaburo Miyata, School of Dentistry, The Autonomous University of the State of Mexico, Toluca, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norma Leticia","family":"Robles-Bermeo","sequence":"additional","affiliation":[{"name":"The Advanced Studies and Research Center in Dentistry Dr. Keisaburo Miyata, School of Dentistry, The Autonomous University of the State of Mexico, Toluca, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wael Hegazy","family":"Hassan Moustafa","sequence":"additional","affiliation":[{"name":"School of Dentistry, The Autonomous University of the State of Mexico, Toluca, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo Eduardo","family":"Medina-Sol\u00eds","sequence":"additional","affiliation":[{"name":"The Advanced Studies and Research Center in Dentistry Dr. Keisaburo Miyata, School of Dentistry, The Autonomous University of the State of Mexico, Toluca, Mexico"},{"name":"The Academic Area of Dentistry, The Institute of Health Sciences, The Autonomous University of the State of Hidalgo, Pachuca, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,3,23]]},"reference":[{"key":"R1-20240901","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.cden.2017.11.003","article-title":"Fluorides and other preventive strategies for tooth decay","volume":"62","author":"Horst","year":"2018","journal-title":"Dent Clin North Am"},{"key":"R2-20240901","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jdent.2018.05.002","article-title":"The influence of hardness and chemical composition on enamel demineralization and subsequent remineralization","volume":"75","author":"Alkattan","year":"2018","journal-title":"J Dent"},{"key":"R3-20240901","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/sj.bdj.2016.865","article-title":"The oral microbiome \u2013 An update for oral healthcare professionals","volume":"221","author":"Kilian","year":"2016","journal-title":"Br Dent J"},{"key":"R4-20240901","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/978-3-319-31248-4_4","article-title":"The Oral Microbiota","volume":"902","author":"Arweiler","year":"2016","journal-title":"Adv Exp Med Biol"},{"key":"R5-20240901","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.pcl.2018.05.014","article-title":"The role of fluoride in the prevention of tooth decay","volume":"65","author":"Pollick","year":"2018","journal-title":"Pediatr Clin North Am"},{"key":"R6-20240901","first-page":"394","article-title":"Silver diamine fluoride: Changing the caries management paradigm and potential societal impact","volume":"78","author":"Wright","year":"2017","journal-title":"N C Med J"},{"key":"R7-20240901","first-page":"77","article-title":"Bactericidal effectiveness of silver diamino fluoride at different concentrations on cariogenic strectoocci in saliva and dentin samples from schoolchildren. 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