{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:43:58Z","timestamp":1786725838881,"version":"build-2736575974"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:p>Ulcerated lesions have been observed in SARS-CoV-2 patients and their treatment is a challenge. We aim to report the treatment of oral lesions with low-level laser therapy (LLLT) in a patient with SARS-CoV-2. The patient diagnosed with COVID-19 was admitted to the intensive care unit, on mechanical ventilation, and on a nasogastric tube diet that persisted due to oral lesions. Painful ulcerated lesions, clinically diagnosed as viral ulcer, were found on the tongue, palate, labial commissure, and oropharynx during the oral evaluation. An antimicrobial photodynamic therapy with methylene blue and red laser (high energy) was performed, followed by treatment with LLLT with red laser. Significant clinical improvement of the lesions was observed after seven sessions of LLLT, with the oral diet being reestablished. Oral mucosal lesions in patients with COVID-19 are usually symptomatic and with onset after systemic symptoms. LLLT has been used in the management of these lesions, with promising results.<\/jats:p>","DOI":"10.4103\/ccd.ccd_399_23","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T15:43:22Z","timestamp":1720539802000},"page":"138-142","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Treatment of Ulcerative Lesions with Low-level Laser Therapy in a Patient with SARS-CoV-2"],"prefix":"10.4103","volume":"15","author":[{"given":"Evllen do Vale","family":"Castro","sequence":"first","affiliation":[{"name":"Christus University Center, Fortaleza, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joao Victor de Paula","family":"Freitas","sequence":"additional","affiliation":[{"name":"Christus University Center, Fortaleza, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Artur Forte","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Christus University Center, Fortaleza, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Alexandre","family":"Maia","sequence":"additional","affiliation":[{"name":"Christus University Center, Fortaleza, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thinali Sousa","family":"Dantas","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Christus University Center, Fortaleza, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarissa Pessoa Fernandes","family":"Forte","sequence":"additional","affiliation":[{"name":"Christus University Center, Fortaleza, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,7,10]]},"reference":[{"key":"R1-20260507","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.bj.2020.05.016","article-title":"Is there an association between oral health and severity of COVID-19 complications?","volume":"43","author":"Botros","year":"2020","journal-title":"Biomed J"},{"key":"R2-20260507","doi-asserted-by":"crossref","first-page":"9473","DOI":"10.34119\/bjhrv4n2-441","article-title":"Dentist\u2019s role in the care of patients in intensive care units during the Covid-19 pandemic","volume":"4","author":"Carvalho","year":"2021","journal-title":"Braz J Health Rev"},{"key":"R3-20260507","doi-asserted-by":"crossref","first-page":"18.","DOI":"10.1051\/mbcb\/2020011","article-title":"Oral manifestation of COVID-19 as an inaugural symptom?","volume":"26","author":"Chaux Bodard","year":"2020","journal-title":"J Oral Med Oral Surg"},{"key":"R5-20260507","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/scd.12520","article-title":"Oral mucosal lesions in patients with SARS-CoV-2 infection. 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