{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:29:51Z","timestamp":1786649391760,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>This article highlights a unique case of Plummer\u2013Vinson syndrome (PVS), also known as Paterson Brown-Kelly Syndrome. PVS is associated with a triad of symptoms, including microcytic hypochromic anemia, esophageal strictures, and dysphagia. It is commonly found in middle-aged women, particularly in the fourth and fifth decades of life, and is rarely reported in males. We present the case of a 49-year-old female patient who exhibited the classic symptoms of PVS. Given that PVS is a precancerous condition with a high potential for malignancy, early diagnosis is crucial for a better prognosis. Surveillance endoscopy and barium swallow test are recommended for monitoring. Iron repletion often improves dysphagia, and in some cases, esophageal dilatation is used to provide symptomatic relief. The mutual interaction of systemic and oral health is often underestimated, especially by patients in developing countries. Therefore, this report emphasizes the importance of thorough medical history taking and its relevance to dental health and treatment.<\/jats:p>","DOI":"10.4103\/ccd.ccd_448_24","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T17:00:20Z","timestamp":1752512420000},"page":"132-135","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Unmasking Plummer\u2013Vinson Syndrome: A Rare Case Report"],"prefix":"10.4103","volume":"16","author":[{"given":"B.","family":"Radhika","sequence":"first","affiliation":[{"name":"Associate Professor, Department of Periodontics, Chettinad Dental College and Research Institute, Kancheepuram, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aswini","family":"Sekar","sequence":"additional","affiliation":[{"name":"Project Research Scientist, National Centre for Disease Informatics and Research (NCDIR), ICMR, Bengaluru, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyanka","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Oral & Maxillofacial Rdiologist, ORAL-D South Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"key":"R1-20260421","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1002\/1097-0142(195705\/06)10:3<470::AID-CNCR2820100309>3.0.CO;2-7","article-title":"Environmental factors in cancer of the upper alimentary tract; a Swedish study with special reference to Plummer-Vinson (Paterson-Kelly) syndrome","volume":"10","author":"Wynder","year":"1957","journal-title":"Cancer"},{"key":"R2-20260421","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1750-1172-1-36","article-title":"Plummer-Vinson syndrome","volume":"1","author":"Novacek","year":"2006","journal-title":"Orphanet J Rare Dis"},{"key":"R3-20260421","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1136\/pgmj.50.582.215","article-title":"The association between webs, iron and post-cricoid carcinoma","volume":"50","author":"Chisholm","year":"1974","journal-title":"Postgrad Med J"},{"key":"R4-20260421","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1053\/bega.2000.0172","article-title":"Squamous cell cancer of the oesophagus","volume":"15","author":"Messmann","year":"2001","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"R5-20260421","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1046\/j.1440-1746.1999.01906.x","article-title":"Gastrointestinal: Upper oesophageal web","volume":"14","author":"Chung","year":"1999","journal-title":"J Gastroenterol Hepatol"},{"key":"R6-20260421","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1017\/S0022215100144263","article-title":"Plummer-Vinson syndrome \u2013 A rare presentation in a child","volume":"113","author":"Mansell","year":"1999","journal-title":"J Laryngol Otol"},{"key":"R8-20260421","first-page":"5","article-title":"Iron Refractory Iron Deficiency Anemia in Dizygotic Twins Due to a Novel TMPRSS6 Gene Mutation in Addition to Polymorphisms Associated With High Susceptibility to Develop Ferropenic Anemia","volume":"19","author":"Pinto","year":"2017","journal-title":"J Investig Med High Impact Case Rep"},{"key":"R10-20260421","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/ajh.24201","article-title":"How we diagnose and treat iron deficiency anemia","volume":"91","author":"Auerbach","year":"2016","journal-title":"Am J Hematol"}],"container-title":["Contemporary Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_448_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:53:31Z","timestamp":1786647211000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_448_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ccd.ccd_448_24","relation":{},"ISSN":["0976-237X","0976-2361"],"issn-type":[{"value":"0976-237X","type":"print"},{"value":"0976-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2024-09-30","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}