{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:21:38Z","timestamp":1787764898004,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Intentional replantation (IR) is a strategic treatment modality involving the deliberate extraction and reinsertion of a tooth following extraoral endodontic management. It is particularly valuable in cases where conventional retreatment or periapical surgery is contraindicated or has previously failed. This case series (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 3) presents three children managed with IR and contemporary biomaterials to enhance periapical healing. Regenerative adjuncts, including platelet-rich fibrin, chitosan, and xenograft bone grafts, were placed to support hard and soft tissue repair. Teeth were atraumatically extracted, followed by retrograde sealing using Biodentine, and subsequently replanted with minimal extraoral time. Stability was ensured using custom acrylic splints. At the 24-month follow-up, all cases exhibited resolution of periapical pathology, preservation of periodontal architecture, and maintenance of functional integrity, although one case displayed slight radiographic evidence of external resorption. These findings emphasize that, when executed with meticulous treatment planning and the use of bioactive materials, IR can serve as a predictable, conservative, and biologically sound approach for preserving natural dentition in growing patients.\n                  <\/jats:p>","DOI":"10.4103\/ccd.ccd_556_25","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T15:00:22Z","timestamp":1781535622000},"page":"126-131","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Platelet-rich Fibrin assisted Intentional Replantation in Children with Two-year Clinical Outcomes: A Case Series"],"prefix":"10.4103","volume":"17","author":[{"given":"Sagun","family":"Aggarwal","sequence":"first","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viraj Jayant","family":"Naik","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liza","family":"Zacharias","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajmohan","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"R1-20260803","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/s41368-024-00337-5","article-title":"Expert consensus on intentional tooth replantation","volume":"17","author":"Lin","year":"2025","journal-title":"Int J Oral Sci"},{"key":"R2-20260803","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3390\/healthcare11010011","article-title":"Intentional replantation of single-rooted and multi-rooted teeth: A systematic review","volume":"11","author":"Pisano","year":"2022","journal-title":"Healthcare (Basel)"},{"key":"R4-20260803","first-page":"e57737","article-title":"Intentional replantation as a viable option for crown-root fracture in maxillary central incisor: A case report","volume":"16","author":"Khubchandani","year":"2024","journal-title":"Cureus"},{"key":"R5-20260803","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.joen.2008.01.002","article-title":"A review of factors influencing treatment planning decisions of single-tooth implants versus preserving natural teeth with nonsurgical endodontic therapy","volume":"34","author":"Iqbal","year":"2008","journal-title":"J Endod"},{"key":"R6-20260803","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.2106\/00004623-200707000-00027","article-title":"Prevention of perioperative infection","volume":"89","author":"Fletcher","year":"2007","journal-title":"J Bone Joint Surg Am"},{"key":"R7-20260803","doi-asserted-by":"crossref","first-page":"5111","DOI":"10.3390\/jcm11175111","article-title":"Intentional replantation as a starting approach for a multidisciplinary treatment of a mandibular second molar: A case report","volume":"11","author":"Santos","year":"2022","journal-title":"J Clin Med"},{"key":"R8-20260803","first-page":"10","article-title":"Biocompatibility and sealing ability of mineral trioxide aggregate and biodentine as root-end filling material: A systematic review","volume":"21","author":"Solanki","year":"2018","journal-title":"J Conserv Dent"},{"key":"R9-20260803","first-page":"34","article-title":"A comprehensive clinical review of platelet rich fibrin (PRF) and its role in promoting tissue healing and regeneration in dentistry. Part 1: Definition, development, biological characteristics and function","volume":"6","author":"Hartshorne","year":"2018","journal-title":"Int Dent Afr Ed"},{"key":"R10-20260803","doi-asserted-by":"crossref","first-page":"172","DOI":"10.3390\/biomimetics10030172","article-title":"Applications of platelet-rich fibrin (PRF) membranes alone or in combination with biomimetic materials in oral regeneration: A narrative review","volume":"10","author":"Valenzuela-Mencia","year":"2025","journal-title":"Biomimetics (Basel)"},{"key":"R11-20260803","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1097\/SCS.0000000000009328","article-title":"The effect of advanced platelet-rich fibrin in tissue regeneration in reconstructive and graft surgery: A systematic review","volume":"34","author":"Pereira","year":"2023","journal-title":"J Craniofac Surg"},{"key":"R12-20260803","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jobcr.2021.01.016","article-title":"Advanced platelet-rich fibrin plus and osseous bone graft for socket preservation and ridge augmentation: A randomized control clinical trial","volume":"11","author":"Yewale","year":"2021","journal-title":"J Oral Biol Craniofac Res"},{"key":"R13-20260803","first-page":"1","article-title":"A general overview of chitosan and its use in dentistry","volume":"5","author":"Erpa\u00e7al","year":"2019","journal-title":"Int Biol Biomed J"},{"issue":"Suppl 1","key":"R14-20260803","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1111\/aej.12707","article-title":"Outcome of intentional replantation of endodontically treated teeth with periapical pathosis: A systematic review and meta-analysis","volume":"49","author":"Javed","year":"2023","journal-title":"Aust Endod J"},{"key":"R15-20260803","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.joen.2017.08.002","article-title":"Intentional replantation techniques: A critical review","volume":"44","author":"Becker","year":"2018","journal-title":"J Endod"},{"key":"R16-20260803","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1016\/j.joen.2016.05.010","article-title":"Survival rate of teeth with a C-shaped canal after intentional replantation: A study of 41 cases for up to 11 years","volume":"42","author":"Jang","year":"2016","journal-title":"J Endod"},{"key":"R17-20260803","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/iej.13456","article-title":"European society of endodontology position statement: Surgical extrusion, intentional replantation and tooth autotransplantation","volume":"54","author":"Plotino","year":"2021","journal-title":"Int Endod J"},{"key":"R18-20260803","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1111\/iej.12268","article-title":"Clinical outcome of intentional replantation with preoperative orthodontic extrusion: A retrospective study","volume":"47","author":"Choi","year":"2014","journal-title":"Int Endod J"}],"container-title":["Contemporary Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_556_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:50:14Z","timestamp":1787763014000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ccd.ccd_556_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/ccd.ccd_556_25","relation":{},"ISSN":["0976-237X","0976-2361"],"issn-type":[{"value":"0976-237X","type":"print"},{"value":"0976-2361","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-09-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-22","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}