{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:30:41Z","timestamp":1787070641480,"version":"build-2736575974"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Carcinoma ex-pleomorphic adenoma (PA) is a complex group of malignant neoplasms arising in PA. When microscopic features of the neoplastic cells are representative of carcinoma, the pathologist can easily make a definite diagnosis, but when worrisome morphology is replaced by metastatic behavior, the metastasizing PA (MPA) is a diagnostic challenge for the pathologist. Here, we present an unusual MPA to cervical lymph nodes and discuss diagnostic challenges.<\/jats:p>","DOI":"10.4103\/drj.drj_274_24","type":"journal-article","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T11:00:50Z","timestamp":1739962850000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Unusual metastasizing pleomorphic adenoma of the parotid gland involving locoregional lymph nodes"],"prefix":"10.4103","volume":"22","author":[{"given":"Faraz","family":"SeyedForootan","sequence":"first","affiliation":[{"name":"School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maziar","family":"Motiee-Langroudi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Cancer Institute Hospital, IKHC, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"Moradi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pouyan","family":"Aminishakib","sequence":"additional","affiliation":[{"name":"Pathology Department, Cancer Institute Hospital, IKHC, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,2]]},"reference":[{"key":"R2-20250524","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1097\/00005537-200112000-00024","article-title":"Histopathology of pleomorphic adenoma in the parotid gland:A prospective unselected series of 100 cases","volume":"111","author":"Stennert","year":"2001","journal-title":"Laryngoscope"},{"key":"R3-20250524","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3941\/jrcr.v9i10.2283","article-title":"Metastatic pleomorphic adenoma to the supraspinatus muscle:A case report and review of a rare aggressive clinical entity","volume":"9","author":"McGarry","year":"2015","journal-title":"J Radiol Case Rep"},{"key":"R4-20250524","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1053\/crad.2000.0541","article-title":"The role of colour flow Doppler in the investigation of the salivary gland tumour","volume":"55","author":"Bradley","year":"2000","journal-title":"Clin Radiol"},{"key":"R5-20250524","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.ejrad.2007.11.021","article-title":"CT and MR images of pleomorphic adenoma in major and minor salivary glands","volume":"69","author":"Kakimoto","year":"2009","journal-title":"Eur J Radiol"},{"key":"R6-20250524","doi-asserted-by":"crossref","first-page":"e531","DOI":"10.1016\/j.joms.2012.06.185","article-title":"Metastasizing pleomorphic adenoma presents intraorally:A case report and review of the literature","volume":"70","author":"Reiland","year":"2012","journal-title":"J Oral Maxillofac Surg"},{"key":"R7-20250524","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1016\/j.jcms.2014.01.014","article-title":"Metastasizing \u201cbenign\u201cpleomorphic salivary adenoma:A dramatic case-report and literature review","volume":"42","author":"Tarsitano","year":"2014","journal-title":"J Craniomaxillofac Surg"},{"key":"R8-20250524","first-page":"E193","article-title":"Metastatic benign pleomorphic adenoma","volume":"13","author":"Rodr\u00edguez-Fern\u00e1ndez","year":"2008","journal-title":"Report of a case and review of the literature. 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