{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T15:42:19Z","timestamp":1705074139478},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T00:00:00Z","timestamp":1569196800000},"content-version":"vor","delay-in-days":905,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Dent"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>This case report aimed to report the progress of preservation therapy and response of symptoms and signs for Stage 0 of bisphosphonate-related osteonecrosis of jaw (BRONJ). A 68-year-old female was recognized having a tooth at the left upper first molar fracture upon medicating bisphosphonate (BP) in 2007. At that time, the extraction of the tooth was an absolute contraindication. Therefore, we performed preservation therapy. We observed the symptoms and signs every month. After 5 months, swelling and redness in the entire first molar tooth were seen and fistula formed partly. Bone exposure was not seen. We administrated antibiotics immediately. As a result, symptoms disappeared. On April 10, 2009, the patient visited us as she felt a sense of incongruity in the lower left first and second molar teeth. Clinically, there were no symptoms of pain. However, we observed the radiolucent finding in about 5 mm diameter at apical position by X-ray photography; we considered a possibility of Stage 0 for BRONJ. We immediately administered medicine for 5 days and the symptoms disappeared. At present, no inflammation with signs and symptoms at the upper left first molar and lower left first, second molar parts is shown. We performed preservation therapy for tooth fracture case medicating of BP. Immediate responses for inflammation and symptoms of the Stage 0 of BRONJ have led to success. Hence, dentists should perform regular clinical observation, and enough education to the patient for BRONJ is necessary.<\/jats:p>","DOI":"10.4103\/ejd.ejd_264_16","type":"journal-article","created":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T06:53:16Z","timestamp":1497855196000},"page":"258-263","source":"Crossref","is-referenced-by-count":2,"title":["A case of tooth fracture occurred upon medicating bisphosphonate for an elderly person: Preservation therapy and responses for Stage 0 of bisphosphonate-related osteonecrosis of jaw"],"prefix":"10.1055","volume":"11","author":[{"given":"Noriko","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Geriatric Dentistry, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Oguchi","sequence":"additional","affiliation":[{"name":"Department of Geriatric Dentistry, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Yamauchi","sequence":"additional","affiliation":[{"name":"Department of Geriatric Dentistry, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuyo","family":"Karube","sequence":"additional","affiliation":[{"name":"Department of Geriatric Dentistry, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukimi","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Geriatric Dentistry, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyasu","family":"Hosoya","sequence":"additional","affiliation":[{"name":"Department of Endodontology, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,9,23]]},"reference":[{"key":"key-10.4103\/1305-7456.208428-1","first-page":"1104","volume-title":"Osteonecrosis of the jaws associated with cancer chemotherapy","author":"Wang","year":"2003","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-2","first-page":"1115","volume-title":"Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: A growing epidemic","author":"Marx","year":"2003","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-3","first-page":"4253","volume-title":"Bisphosphonates and oral cavity avascular bone necrosis","author":"Migliorati","year":"2003","journal-title":"J Clin Oncol"},{"key":"key-10.4103\/1305-7456.208428-4","first-page":"83","volume-title":"Bisphosphonate-associated osteonecrosis of mandibular and maxillary bone: An emerging oral complication of supportive cancer therapy","author":"Migliorati","year":"2005","journal-title":"Cancer"},{"key":"key-10.4103\/1305-7456.208428-5","first-page":"158","volume-title":"Osteonecrosis of the jaws due to bisphosphonate use.A review of 60 cases and treatment proposals","author":"Magopoulos","year":"2007","journal-title":"Am J Otolaryngol"},{"key":"key-10.4103\/1305-7456.208428-6","first-page":"85","volume-title":"The role of surgical resection in the management of bisphosphonate-related osteonecrosis of the jaws","author":"Carlson","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-7","first-page":"2374","volume-title":"Treating bisphosphonate osteonecrosis of the jaws: Is there a role for resection and vascularized reconstruction?","author":"Engroff","year":"2007","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-8","doi-asserted-by":"crossref","unstructured":"Takahashi K, Kawabata A, Koike H, Tohnosu N. A case of osteonecrosis of the maxilla associated with the use of a bisphosphonate. Jpn J Oral Maxillofac Surg 2006;52:416. [In Japanese with English abstract].","DOI":"10.5794\/jjoms.52.416"},{"key":"key-10.4103\/1305-7456.208428-9","first-page":"169","volume-title":"Important aspects concerning alendronate-related osteonecrosis of the jaws: A literature review","author":"Iglesias","year":"2015","journal-title":"Gerodontology"},{"key":"key-10.4103\/1305-7456.208428-10","first-page":"415","volume-title":"Nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in Australia","author":"Mavrokokki","year":"2007","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-11","first-page":"e364","volume-title":"Nationwide survey for bisphosphonate-related osteonecrosis of the jaws in Japan","author":"Urade","year":"2011","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-12","first-page":"365","volume-title":"Bisphosphonate-related osteonecrosis of the jaw: Position paper from the Allied Task Force Committee of Japanese Society for Bone and Mineral Research, Japan Osteoporosis Society of Periodontology, Japanese for Oral and Maxillofacial Radiology and Japanese Society Oral and Maxillofacial Surgeons","author":"Yoneda","year":"2010","journal-title":"J Bone Miner Metab"},{"key":"key-10.4103\/1305-7456.208428-13","first-page":"593","volume-title":"Sinus tracts \u2013 An early sign of bisphosphonate-associated osteonecrosis of the jaws?","author":"Mawardi","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-14","first-page":"2","volume-title":"American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws \u2013 2009 update","author":"Ruggiero","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-15","first-page":"1341","volume-title":"Exposed bone in the palate","author":"Siegel","year":"2007","journal-title":"J Am Dent Assoc"},{"key":"key-10.4103\/1305-7456.208428-16","first-page":"e18","volume-title":"Oral osteonecrosis associated with the use of ibandronate: Report of a case and clinical implications","author":"Migliorati","year":"2008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"key-10.4103\/1305-7456.208428-17","first-page":"759","volume-title":", Goodell GG.Bisphosphonate-associated osteonecrosis of the jaws and endodontic treatment: Two case reports","author":"Sarathy","year":"2005","journal-title":"J Endod"},{"key":"key-10.4103\/1305-7456.208428-18","first-page":"943","volume-title":"Outcome of surgical management of bisphosphonate-related osteonecrosis of the jaws: Review of 33 surgical cases","author":"Stanton","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-19","first-page":"251","volume-title":"Surgical management of bisphosphonate induced osteonecrosis of the jaws","author":"Williamson","year":"2010","journal-title":"Int J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-20","first-page":"1658","volume-title":"Managing the care of patients with bisphosphonate-associated osteonecrosis: An American Academy of Oral Medicine position paper","author":"Migliorati","year":"2005","journal-title":"J Am Dent Assoc"},{"key":"key-10.4103\/1305-7456.208428-21","first-page":"527","volume-title":"Osteonecrosis of the jaws associated with the use of bisphosphonates: A review of 63 cases","author":"Ruggiero","year":"2004","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-22","first-page":"508","volume-title":"Bisphosphonate-associated osteonecrosis: A long-term complication of bisphosphonate treatment","author":"Migliorati","year":"2006","journal-title":"Lancet Oncol"},{"key":"key-10.4103\/1305-7456.208428-23","first-page":"103","volume-title":"Bisphosphonate therapy for bone loss in patients with osteoporosis and periodontal disease: Clinical perspectives and review of the literature","author":"Palomo","year":"2006","journal-title":"Quintessence Int"},{"key":"key-10.4103\/1305-7456.208428-24","first-page":"44","volume-title":"Intravenous bisphosphonate therapy and bisphosphonate-related osteonecrosis of the jaws","author":"Dodson","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"key":"key-10.4103\/1305-7456.208428-25","first-page":"177","volume-title":"Dental implications of bisphosphonate-related osteonecrosis","author":"Saldanha","year":"2012","journal-title":"Gerodontology"},{"key":"key-10.4103\/1305-7456.208428-26","first-page":"625","volume-title":"Non-exposed bisphosphonate-related osteonecrosis of the jaw: A critical assessment of current definition, staging, and treatment guidelines","author":"Patel","year":"2012","journal-title":"Oral Dis"},{"key":"key-10.4103\/1305-7456.208428-27","first-page":"362","volume-title":"Relevance of a prolonged preoperative antibiotic regime in the treatment of bisphosphonate-related osteonecrosis of the jaw","author":"Hoefert","year":"2011","journal-title":"J Oral Maxillofac Surg"}],"container-title":["European Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/ejd.ejd_264_16.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T22:50:36Z","timestamp":1569279036000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.4103\/ejd.ejd_264_16"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":27,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2019,9,23]]},"published-print":{"date-parts":[[2017,4]]}},"URL":"https:\/\/doi.org\/10.4103\/ejd.ejd_264_16","relation":{},"ISSN":["1305-7456","1305-7464"],"issn-type":[{"value":"1305-7456","type":"print"},{"value":"1305-7464","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4]]}}}