{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:25:12Z","timestamp":1789680312258,"version":"4.0.1"},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T00:00:00Z","timestamp":1569196800000},"content-version":"vor","delay-in-days":357,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Dent"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          Objective: Chronic periodontitis (CP) is a common inflammatory disease that causes destruction to the supporting tissues of the teeth. Many treatment modalities tried to stop the disease progression. Platelet-rich plasma (PRP) is one of the regenerative methods that used in adjunct to conventional periodontal treatment. The aim of this study was to evaluate the anti-inflammatory effect of PRP by monitoring the lymphocyte count before and after its application to the periodontal pocket. Materials and Methods: Twenty patients, with CP and a pocket depth equal to or deeper than 4 mm, subjected to scaling, root planing, and PRP injection into the pocket. The lymphocyte count measured before and after 1 month from PRP application. Clinical periodontal parameters were taken during two visits (1 month apart), with customized stent fabrication. Results: All clinical periodontal parameters showed a reduction in their value following 1 month of PRP application. . There was a noticeable reduction in lymphocyte count from (mean 2.47 \u00b1 0.91) to (mean 1.94 \u00b1 0.77). Conclusion: In addition to its traditional uses, PRP has a great role in the periodontal treatment by its anti-inflammatory effect.<\/jats:p>","DOI":"10.4103\/ejd.ejd_49_18","type":"journal-article","created":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T10:23:25Z","timestamp":1538562205000},"page":"528-531","source":"Crossref","is-referenced-by-count":31,"title":["The anti-inflammatory effect of the platelet-rich plasma in the periodontal pocket"],"prefix":"10.1055","volume":"12","author":[{"given":"Lubaba A.","family":"Abdul Ameer","sequence":"additional","affiliation":[{"name":"Department of Periodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zainab J.","family":"Raheem","sequence":"additional","affiliation":[{"name":"Department of Periodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saif Saadedeen","family":"Abdulrazaq","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Baghdad, Baghdad, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basima Gh.","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Periodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maysaa Mahdi","family":"Nasser","sequence":"additional","affiliation":[{"name":"AL-Sader Dental Specialized Center, Baghdad, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azza Wala Aldeen","family":"Khairi","sequence":"additional","affiliation":[{"name":"Department of Periodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,9,23]]},"reference":[{"key":"key-10.4103\/1305-7456.242607-1","doi-asserted-by":"crossref","unstructured":"Novak MJ, Novak KF. Chronic periodontitis. In: Newman MG, Takei HH, Klokkevold ER, Carranza FA, editors. Carranza's Clinical Periodontology. 11th ed. Missouri: Saunders, An Imprint of Elsevier Inc.; 2012. p. 160.","DOI":"10.1016\/B978-1-4377-0416-7.00016-0"},{"key":"key-10.4103\/1305-7456.242607-2","first-page":"1075","volume-title":"Progression of destructive periodontal diseases in three urban minority populations: Role of clinical and demographic factors","author":"Craig","year":"2003","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/1305-7456.242607-3","first-page":"4","volume-title":"Autologous platelets as a source of proteins for healing and tissue regeneration","author":"Anitua","year":"2004","journal-title":"Thromb Haemost"},{"key":"key-10.4103\/1305-7456.242607-4","first-page":"e119","volume-title":"Intentional replantation for a periodontally involved hopeless incisor by using autologous platelet-rich plasma","author":"T\u00f6z\u00fcm","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"key-10.4103\/1305-7456.242607-5","first-page":"159","volume-title":"White blood cell count in different stages of chronic periodontitis","author":"Pejci\u0107","year":"2011","journal-title":"Acta Clin Croat"},{"key":"key-10.4103\/1305-7456.242607-6","first-page":"92","volume-title":"A systematic review of the effect of surgical debridement vs non-surgical debridement for the treatment of chronic periodontitis","author":"Heitz-Mayfield","year":"2002","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/1305-7456.242607-7","first-page":"1668","volume-title":"Treatment of intrabony defects with bovine-derived xenograft alone and in combination with platelet-rich plasma: A randomized clinical trial","author":"Hanna","year":"2004","journal-title":"J Periodontol"},{"key":"key-10.4103\/1305-7456.242607-8","first-page":"38","volume-title":"Consensus report: chronic periodontitis.Annals Periodontol","author":"Lindhe","year":"1999","journal-title":""},{"key":"key-10.4103\/1305-7456.242607-9","first-page":"525","volume-title":"Optimizing platelet-rich plasma gel formation by varying time and gravitational forces during centrifugation","author":"Jo","year":"2013","journal-title":"J Oral Implantol"},{"key":"key-10.4103\/1305-7456.242607-10","first-page":"705","volume-title":"Platelet-rich plasma combined with decalcified freeze-dried bone allograft for the treatment of noncontained human intrabony periodontal defects: A randomized controlled split-mouth study","author":"Agarwal","year":"2014","journal-title":"Int J Periodontics Restorative Dent"},{"key":"key-10.4103\/1305-7456.242607-11","unstructured":"International Business Machines Corporation. Released International Business Machines SPSS Statistics for Windows, Version 20.0. Armonk, NY: International Business Machines Corporation; 2011."},{"key":"key-10.4103\/1305-7456.242607-12","first-page":"562","volume-title":"Platelet-rich plasma for periodontal regeneration in the treatment of intrabony defects: A meta-analysis on prospective clinical trials","author":"Rosell\u00f3-Camps","year":"2015","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"key-10.4103\/1305-7456.242607-13","first-page":"661","volume-title":"Platelet-rich plasma: Growth factors and pro- and anti-inflammatory properties","author":"El-Sharkawy","year":"2007","journal-title":"J Periodontol"},{"key":"key-10.4103\/1305-7456.242607-14","first-page":"469","volume-title":"Effect of platelet-rich plasma concentrations on the proliferation of periodontal cells: An in vitro study","author":"Tavassoli-Hojjati","year":"2016","journal-title":"Eur J Dent","ISSN":"https:\/\/id.crossref.org\/issn\/1305-7456","issn-type":"print"},{"key":"key-10.4103\/1305-7456.242607-15","first-page":"91","volume-title":"Effects of platelet rich plasma (PRP) on human gingival fibroblast, osteoblast and periodontal ligament cell behaviour","author":"Kobayashi","year":"2017","journal-title":"BMC Oral Health"},{"key":"key-10.4103\/1305-7456.242607-16","first-page":"79","volume-title":"Enhanced activation of platelets with abnormal release of RANTES in human immunodeficiency virus type 1 infection","author":"Holme","year":"1998","journal-title":"FASEB J"}],"container-title":["European Journal of Dentistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.4103\/ejd.ejd_49_18.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T22:38:23Z","timestamp":1569278303000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.4103\/ejd.ejd_49_18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":16,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2019,9,23]]},"published-print":{"date-parts":[[2018,10]]}},"URL":"https:\/\/doi.org\/10.4103\/ejd.ejd_49_18","relation":{},"ISSN":["1305-7456","1305-7464"],"issn-type":[{"value":"1305-7456","type":"print"},{"value":"1305-7464","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}