{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:40:06Z","timestamp":1786653606111,"version":"build-2736575974"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"Abstract<\/jats:title>\n \n Objectives:<\/jats:title>\n \n The Food and Drug Administration banned the use of transvaginal mesh for pelvic organ prolapse (POP) repair due to safety and efficacy concerns. The present study aimed to evaluate the safety and efficacy of a novel lightweight minimesh (SERATOM\n \u00ae<\/jats:sup>\n MN) for transvaginal repair of significant primary or recurrent POP.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n A cohort study of 134 consecutive patients (mean age: 61.7 \u00b1 9.4 years, range: 46\u201388) who underwent transvaginal minimesh repair (SERATOM\n \u00ae<\/jats:sup>\n MN) for Stage III or IV POP was retrospectively analyzed. At 10 years postoperatively, a telephone survey was conducted to assess long-term outcomes. The mean postoperative follow-up was 9.8 \u00b1 0.45 years (range: 9.4\u201310.9 years). A comparison was made between 99 (73.9%) patients who underwent primary mesh-assisted POP repair versus 35 (26.1%) patients who underwent mesh-assisted surgery for recurrent POP. Primary outcomes comprised postoperative complications, POP recurrence rate, and subjective long-term satisfaction.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The mean duration of surgery and blood loss was 30.8 min and 32.4 ml, respectively. Most patients (98.5%) were discharged on the day of surgery or the day after. There were no significant intra- or early postoperative complications, except for one case of postoperative perineal hematoma that was managed conservatively. Of the initial 134 patients, 110 (82%) were available for long-term follow-up. There were no mesh erosions.\n De novo<\/jats:italic>\n dyspareunia occurred in 6.4%. Rates of recurrent POP repair were similar among patients who had mesh-assisted repair after previous pelvic surgery (23.3%) and those who had primary mesh-assisted repair (15%).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n Transvaginal SERATOM\n \u00ae<\/jats:sup>\n MN minimesh is a safe, effective, and durable surgical option for significant POP repair.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/gmit.gmit-d-24-00016","type":"journal-article","created":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T13:00:31Z","timestamp":1768309231000},"page":"30-35","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Size Does Matter: Long-term Efficacy and Safety of Minimesh in Transvaginal Pelvic Organ Prolapse Repair"],"prefix":"10.4103","volume":"15","author":[{"given":"Ronen Samuel","family":"Gold","sequence":"first","affiliation":[{"name":"Urogynecology Unit, Lis Women\u2019s Hospital, Tel Aviv Medical Center, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonatan","family":"Neuman","sequence":"additional","affiliation":[{"name":"Medical School, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Menahem","family":"Neuman","sequence":"additional","affiliation":[{"name":"The Urogynecology Service, Assuta Medical Centers, Medical School, Ben Gurion University, Medical School, Negev Be\u2019er Sheva, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asnat","family":"Groutz","sequence":"additional","affiliation":[{"name":"Urogynecology Unit, Lis Women\u2019s Hospital, Tel Aviv Medical Center, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,13]]},"reference":[{"key":"R1-20260209","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1097\/AOG.0000000000000286","article-title":"Lifetime risk of stress urinary incontinence or pelvic organ prolapse surgery","volume":"123","author":"Wu","year":"2014","journal-title":"Obstet Gynecol"},{"key":"R2-20260209","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.ajog.2004.06.109","article-title":"Risk factors for prolapse recurrence after vaginal repair","volume":"191","author":"Whiteside","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"R3-20260209","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.urology.2015.08.022","article-title":"Trends in mesh use for pelvic organ prolapse repair from the Medicare database","volume":"86","author":"Wang","year":"2015","journal-title":"Urology"},{"key":"R7-20260209","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1007\/s00345-016-1792-8","article-title":"Efficacy and safety of skeletonized mesh implants for advanced pelvic organ prolapse: 12-month follow-up","volume":"34","author":"Weintraub","year":"2016","journal-title":"World J Urol"},{"key":"R8-20260209","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1080\/01443615.2021.1916808","article-title":"Outcomes of a fixed skeletonised mini mesh implant for pelvic organ prolapse repair with uterine preservation","volume":"42","author":"Levor","year":"2022","journal-title":"J Obstet Gynaecol"},{"key":"R9-20260209","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S0002-9378(96)70243-0","article-title":"The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction","volume":"175","author":"Bump","year":"1996","journal-title":"Am J Obstet Gynecol"},{"key":"R10-20260209","doi-asserted-by":"crossref","first-page":"575.e1","DOI":"10.1016\/j.ajog.2007.12.035","article-title":"Validation of decision-making outcomes for female pelvic floor disorders","volume":"198","author":"Sung","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"R11-20260209","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1007\/s00192-022-05442-9","article-title":"Subjective outcomes 12 years after transvaginal mesh versus native tissue repair in women with recurrent pelvic organ prolapse;a randomized controlled trial","volume":"34","author":"Kluivers","year":"2023","journal-title":"Int Urogynecol J"},{"key":"R12-20260209","first-page":"595","article-title":"Comparison of long-term clinical outcomes between transvaginal mesh and pelvic floor reconstruction with native tissue repair in the treatment of advanced pelvic organ prolapse","volume":"58","author":"Wu","year":"2023","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"R13-20260209","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00192-022-05308-0","article-title":"PROSPECT: 4- and 6-year follow-up of a randomised trial of surgery for vaginal prolapse","volume":"34","author":"Reid","year":"2023","journal-title":"Int Urogynecol J"},{"key":"R14-20260209","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1007\/s00192-011-1384-5","article-title":"Incidence and management of graft erosion, wound granulation, and dyspareunia following vaginal prolapse repair with graft materials: A systematic review","volume":"22","author":"Abed","year":"2011","journal-title":"Int Urogynecol J"},{"key":"R15-20260209","doi-asserted-by":"crossref","first-page":"622","DOI":"10.3390\/jpm14060622","article-title":"Complications of pelvic prolapse surgery using mesh: A systematic review","volume":"14","author":"Dabica","year":"2024","journal-title":"J Pers Med"},{"key":"R16-20260209","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1097\/AOG.0000000000004794","article-title":"Transvaginal mesh compared with native tissue repair for pelvic organ prolapse","volume":"139","author":"Kahn","year":"2022","journal-title":"Obstet Gynecol"},{"key":"R18-20260209","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1001\/jamasurg.2024.1206","article-title":"Apical suspension repair for vaginal vault prolapse: A randomized clinical trial","volume":"159","author":"Menefee","year":"2024","journal-title":"JAMA Surg"},{"key":"R19-20260209","doi-asserted-by":"crossref","first-page":"204","DOI":"10.4103\/GMIT.GMIT_32_19","article-title":"Effect of pelvic organ prolapse reconstructive mesh surgery on the quality of life of Turkish patients: A prospective study","volume":"9","author":"Sukgen","year":"2020","journal-title":"Gynecol Minim Invasive Ther"}],"container-title":["Gynecology and Minimally Invasive Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/gmit.GMIT-D-24-00016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:39:49Z","timestamp":1786649989000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/gmit.GMIT-D-24-00016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/gmit.gmit-d-24-00016","relation":{},"ISSN":["2213-3070","2213-3089"],"issn-type":[{"value":"2213-3070","type":"print"},{"value":"2213-3089","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2024-08-23","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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