{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:21:52Z","timestamp":1787757712186,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Ovarian leiomyomas are very rare. We report the case of a primary ovarian leiomyoma accompanied by multiple uterine leiomyomas. A 50-year-old woman was referred to our department for heavy menstruation, and a hot spot in the uterine lumen was observed on positron emission tomography\u2013computed tomography (PET-CT). Cervical and endometrial cytology and tumor marker tests were negative. Pelvic magnetic resonance imaging revealed an endometrial polyp and submucosal leiomyoma in the uterine lumen and a 5-cm right ovarian tumor. Laparoscopic total hysterectomy, right salpingo-oophorectomy, and left salpingectomy were performed for radical treatment. Histopathology showed that ovarian tumors contained interlacing bundles of fusiform cells encircled by normal ovarian tissue. Immunohistochemical staining showed strong and diffuse positive staining for \u03b1-smooth muscle actin. We diagnosed the tumor as a primary ovarian leiomyoma because the leiomyoma was localized in the ovary and was larger than the size of uterine leiomyomas. No metastatic lesion was found on PET-CT. There was no tumor recurrence at the 6-month follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/gmit.gmit_97_19","type":"journal-article","created":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T01:08:37Z","timestamp":1639357717000},"page":"50-52","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":15,"title":["Primary Ovarian Leiomyoma Associated with Multiple Uterine Leiomyomas"],"prefix":"10.4103","volume":"10","author":[{"given":"Yoshihiro","family":"Kitamura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumitake","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuya","family":"Kokabu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taisuke","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izumi","family":"Kusuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo","family":"Kitawaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20240830","first-page":"1152","article-title":"A huge primary ovarian leiomyoma with degenerative changes \u2013 An unusual","volume":"7","author":"Agrawal","year":"2013","journal-title":"J Clin Diagn Res"},{"key":"R2-10-20240830","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jpag.2013.07.011","article-title":"Primary ovarian leiomyoma in a premenarchal adolescent: First reported case","volume":"27","author":"Blue","year":"2014","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"R3-10-20240830","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.ijscr.2014.07.020","article-title":"Primary ovarian leiomyoma: A case report","volume":"5","author":"Taskin","year":"2014","journal-title":"Int J Surg Case Rep"},{"key":"R4-10-20240830","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jpag.2007.07.001","article-title":"Primary ovarian leiomyoma: A rare cause of ovarian tumor in adolescence","volume":"21","author":"Wei","year":"2008","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"R5-10-20240830","first-page":"3","article-title":"Postmenopausal huge ovarian leiomyoma: A rare presentation","volume":"8","author":"Sasikala R Rupavami","year":"2014","journal-title":"J Clin Diagn Res"},{"key":"R6-10-20240830","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s00261-004-0202-7","article-title":"Birateral ovarian leiomyomas: CT and MRI feature","volume":"30","author":"Yoshitake","year":"2005","journal-title":"Abdom Imaging"},{"key":"R7-10-20240830","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1259\/bjr\/54090919","article-title":"MRI appearance of primary giant ovarian leiomyoma in a hysterectomized woman","volume":"79","author":"Tamada","year":"2006","journal-title":"Br J Radiol"},{"key":"R8-10-20240830","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1006\/gyno.2000.5859","article-title":"Endometrial histopathology in 700 patients treated with tamoxifen for breast cancer","volume":"78","author":"Deligdisch","year":"2000","journal-title":"Gynecol Oncol"},{"key":"R9-10-20240830","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ejogrb.2008.07.001","article-title":"Tamoxifen and growth of an extrauterine leiomyoma","volume":"141","author":"Bayya","year":"2008","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R10-10-20240830","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1186\/s13104-017-2998-6","article-title":"Unexpected pulmonary tumor: Metastasis from a benign uterine leiomyoma in a post-menopausal woman: A case report","volume":"10","author":"Efared","year":"2017","journal-title":"BMC Res Notes"}],"container-title":["Gynecology and Minimally Invasive Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/GMIT.GMIT_97_19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:49:22Z","timestamp":1787755762000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/GMIT.GMIT_97_19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/gmit.gmit_97_19","relation":{},"ISSN":["2213-3070"],"issn-type":[{"value":"2213-3070","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}