{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:01:15Z","timestamp":1787169675711,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The vast majority of literature on atrial fibrillation (AF) is based on studies from the developed world that mainly includes Caucasian patients. Data on AF in other ethnicities is very limited. The aim of this hospital-based study is to evaluate the effect of concomitant hypertension (HTN) on the characteristics and outcomes of Middle Eastern Arab and South Asian patients with AF in the state of Qatar.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods and Results:<\/jats:title>\n                    <jats:p>\n                      During the 20-year period, 3850 AF patients were hospitalized; 1483 (38.5%) had HTN, and 2367 (61.5%) without HTN. Patients with HTN were 11 years older, compared to non-HTN patients, and had a significantly higher prevalence of diabetes mellitus, chronic kidney disease, and dyslipidemia, compared to non-HTN patients. Furthermore, underlying coronary artery disease and heart failure were significantly more common but not valvular and rheumatic heart diseases which were more common in those without HTN. The rates of in-hospital mortality and stroke were significantly higher in the presence of HTN (5.3% versus 3.5%, and 0.7% versus 0.2% respectively,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001), compared to non-HTN patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>HTN is significantly associated with more comorbidities and worse clinical outcomes when it coexists with AF in hospitalized Middle Eastern Arab and South Asian patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/heartviews.heartviews_33_21","type":"journal-article","created":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T01:37:25Z","timestamp":1644543445000},"page":"256-263","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Hypertension in Middle Eastern Arab and South Asian Patients with Atrial Fibrillation"],"prefix":"10.4103","volume":"22","author":[{"given":"Amar M.","family":"Salam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imtiaz","family":"Salim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasha","family":"Kaddoura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajvir","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nidal","family":"Asaad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Awad","family":"Al-Qahtani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jassim","family":"Al Suwaidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajar A.","family":"AlBinali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20240902","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1093\/eurheartj\/ehi825","article-title":"Prevalence, incidence and lifetime risk of atrial fibrillation: The Rotterdam study","volume":"27","author":"Heeringa","year":"2006","journal-title":"Eur Heart J"},{"key":"R2-4-20240902","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1161\/01.CIR.98.10.946","article-title":"Impact of atrial fibrillation on the risk of death: The Framingham Heart Study","volume":"98","author":"Benjamin","year":"1998","journal-title":"Circulation"},{"key":"R3-4-20240902","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1023\/B:CEPR.0000012382.81986.47","article-title":"Significance of atrial fibrillation during acute myocardial infarction, and its current management: Insights from the GUSTO-3 trial","volume":"7","author":"Wong","year":"2003","journal-title":"Card Electrophysiol Rev"},{"key":"R4-4-20240902","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1161\/CIRCHEARTFAILURE.111.965681","article-title":"Presence of atrial fibrillation is independently associated with adverse outcomes in patients hospitalized with heart failure: An analysis of get with the guidelines-heart failure","volume":"5","author":"Mountantonakis","year":"2012","journal-title":"Circ Heart Fail"},{"key":"R5-4-20240902","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1159\/000316886","article-title":"Pathophysiological determinants of worse stroke outcome in atrial fibrillation","volume":"30","author":"Tu","year":"2010","journal-title":"Cerebrovasc Dis"},{"key":"R6-4-20240902","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4172\/2324-8602.1000104","article-title":"Systematic review of atrial fibrillation in patients with chronic kidney disease: Prevalence, incidence, morbidity and mortality","volume":"1","author":"Salim","year":"2012","journal-title":"Int J Cardiovasc Res"},{"key":"R7-4-20240902","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.amjcard.2010.04.035","article-title":"Incidence, risk factors, and clinical outcomes of atrial fibrillation and atrial flutter after heart transplantation","volume":"106","author":"Dasari","year":"2010","journal-title":"Am J Cardiol"},{"key":"R9-4-20240902","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1001\/jama.1994.03510350050036","article-title":"Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study","volume":"271","author":"Benjamin","year":"1994","journal-title":"JAMA"},{"key":"R10-4-20240902","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1524-6175.2003.02464.x","article-title":"The burden of uncontrolled hypertension: Morbidity and mortality associated with disease progression","volume":"5","author":"Cushman","year":"2003","journal-title":"J Clin Hypertens (Greenwich"},{"key":"R11-4-20240902","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1161\/CIRCRESAHA.117.309732","article-title":"Atrial fibrillation: Epidemiology, pathophysiology, and clinical outcomes","volume":"120","author":"Staerk","year":"2017","journal-title":"Circ Res"},{"key":"R12-4-20240902","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.31083\/j.rcm2204127","article-title":"Atrial fibrillation in Middle Eastern Arabs and South Asians: A scoping review","volume":"22","author":"Salam","year":"2021","journal-title":"Rev Cardiovasc Med"},{"key":"R14-4-20240902","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.ijcard.2004.05.024","article-title":"Thrombolytic therapy use for acute myocardial infarction and outcome in Qatar","volume":"102","author":"Hadi","year":"2005","journal-title":"Int J Cardiol"},{"key":"R15-4-20240902","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jacc.2008.11.013","article-title":"American College of Cardiology Foundation; American Heart Association. 2009 Focused update incorporated into the ACC\/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines Developed in Collaboration with the International Society for Heart and Lung Transplantation","volume":"53","author":"Hunt","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"R16-4-20240902","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1136\/hrt.2003.014746","article-title":"Mortality caused by acute myocardial infarction in Qatari women","volume":"90","author":"Al Suwaidi","year":"2004","journal-title":"Heart"},{"key":"R17-4-20240902","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1161\/01.HYP.0000107251.49515.c2","article-title":"Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure","volume":"42","author":"Chobanian","year":"2003","journal-title":"Hypertension"},{"key":"R19-4-20240902","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/S0272-6386(98)70074-5","article-title":"Serum creatinine levels in the US population: Third National Health and Nutrition Examination Survey","volume":"32","author":"Jones","year":"1998","journal-title":"Am J Kidney Dis"},{"key":"R20-4-20240902","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.ijcard.2006.04.061","article-title":"A cross-sectional study of hypertension in an elderly population (75 years and over) with atrial fibrillation: Secondary analysis of data from the Birmingham Atrial Fibrillation in the Aged (BAFTA) randomised controlled trial","volume":"117","author":"Hurley","year":"2007","journal-title":"Int J Cardiol"},{"key":"R21-4-20240902","doi-asserted-by":"crossref","first-page":"819.e1","DOI":"10.1016\/j.amjmed.2006.10.014","article-title":"Characteristics of hospitalized patients with atrial fibrillation in Taiwan: A nationwide observation","volume":"120","author":"Lee","year":"2007","journal-title":"Am J Med"},{"key":"R22-4-20240902","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1053\/euhj.2000.2511","article-title":"Trends in hospital activity, morbidity and case fatality related to atrial fibrillation in Scotland, 1986-1996","volume":"22","author":"Stewart","year":"2001","journal-title":"Eur Heart J"},{"key":"R23-4-20240902","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.amjcard.2004.04.068","article-title":"Epidemiology and determinants of outcome of admissions for atrial fibrillation in the United States from 1996 to 2001","volume":"94","author":"Khairallah","year":"2004","journal-title":"Am J Cardiol"},{"key":"R24-4-20240902","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.jacc.2006.10.062","article-title":"Mortality trends in patients diagnosed with first atrial fibrillation: A 21-year community-based study","volume":"49","author":"Miyasaka","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"R25-4-20240902","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1093\/europace\/eun369","article-title":"The Registry of the German Competence NETwork on Atrial Fibrillation: Patient characteristics and initial management","volume":"11","author":"Nabauer","year":"2009","journal-title":"Europace"},{"key":"R26-4-20240902","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jstrokecerebrovasdis.2009.04.004","article-title":"Risk factor profiles of stroke, myocardial infarction, and atrial fibrillation: A Japanese Multicenter Cooperative Registry","volume":"19","author":"Uchiyama","year":"2010","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"R27-4-20240902","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1007\/s00392-011-0320-5","article-title":"Management of atrial fibrillation by primary care physicians in Germany: Baseline results of the ATRIUM registry","volume":"100","author":"Meinertz","year":"2011","journal-title":"Clin Res Cardiol"},{"key":"R28-4-20240902","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1136\/heartjnl-2011-300550","article-title":"Symptoms, functional status and quality of life in patients with controlled and uncontrolled atrial fibrillation: Data from the RealiseAF cross-sectional international registry","volume":"98","author":"Steg","year":"2012","journal-title":"Heart"},{"key":"R29-4-20240902","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.amjcard.2011.08.046","article-title":"Insights into management of atrial fibrillation in Asia Pacific gained from baseline data from REgistry on cardiac rhythm disORDers (RecordAF-Asia Pacific [AP]) registry","volume":"109","author":"Amerena","year":"2012","journal-title":"Am J Cardiol"},{"key":"R30-4-20240902","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.ahj.2012.02.015","article-title":"Progression of atrial fibrillation in the REgistry on Cardiac rhythm disORDers assessing the control of Atrial Fibrillation cohort: Clinical correlates and the effect of rhythm-control therapy","volume":"163","author":"De Vos","year":"2012","journal-title":"Am Heart J"},{"key":"R31-4-20240902","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1056\/NEJMoa1105594","article-title":"Stroke and bleeding in atrial fibrillation with chronic kidney disease","volume":"367","author":"Olesen","year":"2012","journal-title":"N Engl J Med"},{"key":"R32-4-20240902","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S0828-282X(06)70265-3","article-title":"Stroke prevention in patients with atrial fibrillation: The diagnosis and management of hypertension by specialists","volume":"22","author":"Healey","year":"2006","journal-title":"Can J Cardiol"},{"key":"R33-4-20240902","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1093\/aje\/155.9.819","article-title":"Increased atrial fibrillation mortality: United States, 1980-1998","volume":"155","author":"Wattigney","year":"2002","journal-title":"Am J Epidemiol"}],"container-title":["Heart Views"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/HEARTVIEWS.HEARTVIEWS_33_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:10:30Z","timestamp":1787166630000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/HEARTVIEWS.HEARTVIEWS_33_21"}},"subtitle":["From a 20-Year Hospital Registry in Qatar (1990-2010)"],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/heartviews.heartviews_33_21","relation":{},"ISSN":["1995-705X"],"issn-type":[{"value":"1995-705X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]}}}