{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:32:14Z","timestamp":1787070734511,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Melanocytes in the hair and melanocytes in the stria vascularis of the inner ear have common origins. Many congenital and acquired disorders of cutaneous pigmentation have auditory abnormalities. There is a paucity of studies on the auditory associations of early graying.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim and Objectives:<\/jats:title>\n                    <jats:p>The aim of the study was to determine the association between early graying and auditory system abnormalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A cross-sectional analytical study was done on 100 patients with early graying and 100 controls. Pure tone audiometry was done at 0.25 to 4 kHz for bone conduction, conventional and high frequencies from 0.25 to 8 kHz for air conduction, and extended high frequencies from 9 kHz to 20 kHz for air conduction in both ears.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Bilateral hearing loss &gt;25 dB was present in three patients with early graying based on the four-frequency average of 0.5, 1, 2, and 4 kHz. Patients with early graying had significantly higher thresholds for hearing except at 0.25 kHz in the right ears and 0.25, 2, 10, and 11 kHz in the left ears.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Limitations:<\/jats:title>\n                    <jats:p>We did not assess cochlear function with otoacoustic emissions, and our study design did not allow us to assess causality and temporal association.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our study found that early graying may be a visible marker of changes in auditory thresholds. Patients with early graying need periodic auditory evaluations and health education to prevent further hearing loss.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/idoj.idoj_1_24","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T13:02:16Z","timestamp":1736859736000},"page":"977-981","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Auditory System Abnormalities in Early Graying of Hair: A Cross-Sectional Study"],"prefix":"10.4103","volume":"15","author":[{"given":"Shubham","family":"Panwar","sequence":"first","affiliation":[{"name":"Department of Dermatology, All India Institute of Medical Sciences, Guntur, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hima","family":"Gopinath","sequence":"additional","affiliation":[{"name":"Department of Dermatology, All India Institute of Medical Sciences, Guntur, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satvinder S.","family":"Bakshi","sequence":"additional","affiliation":[{"name":"Department of ENT and Head and Neck Surgery, All India Institute of Medical Sciences, Guntur, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinoth K.","family":"Kalidoss","sequence":"additional","affiliation":[{"name":"Community and Family Medicine, All India Institute of Medical Sciences, Guntur, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumyajit","family":"Das","sequence":"additional","affiliation":[{"name":"Department of ENT and Head and Neck Surgery, All India Institute of Medical Sciences, Guntur, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jahnavi","family":"Sambangi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, All India Institute of Medical Sciences, Guntur, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramesh","family":"Seepana","sequence":"additional","affiliation":[{"name":"Department of ENT and Head and Neck Surgery, All India Institute of Medical Sciences, Guntur, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,9,20]]},"reference":[{"key":"R1-20251023","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1111\/ced.14649","article-title":"Ocular and auditory abnormalities in patients with vitiligo:A case-control study","volume":"46","author":"Genedy","year":"2021","journal-title":"Clin Exp Dermatol"},{"key":"R2-20251023","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1002\/dneu.22279","article-title":"Development of the stria vascularis and potassium regulation in the human fetal cochlea:Insights into hereditary sensorineural hearing 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