{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:23:59Z","timestamp":1787847839814,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,3]]},"abstract":"\n Objectives:<\/jats:title>\n Psoriasis is a common, chronic, non-communicable skin disease with no clear etiology or cure. Periodontitis is a chronic inflammatory condition which is now known to significantly influence various systemic diseases as an established risk factor. This study aimed at comparatively evaluating the periodontal status of Psoriatic patients vis. a vis. that of age and gender matched systemically healthy volunteers. An attempt was also made to explore a possible association, if any, amongst the two diseases.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n Forty two residents of Chandigarh, suffering from Psoriasis and attending the Psoriasis Clinic of Department of Dermatology & Venereology, Post Graduate Institute of Medical Education & Research, Chandigarh were recruited over a period of 10 months (Case group) and their periodontal status was compared with forty two age and gender matched systemically healthy volunteers (Control group) randomly selected from the Out Patient Department of Periodontics, Dr. Harvansh Singh Judge Institute of Dental Sciences & Hospital, Panjab University, India. Their serum IL-33 levels were evaluated and compared in an attempt to identify an underlying common pathological pathway.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The periodontal status was comparable in the two groups in terms of the debris index (\n p<\/jats:italic>\n = 0.932), calculus index (\n p<\/jats:italic>\n = 0.088), plaque index (\n p<\/jats:italic>\n = 0.097), and mean clinical attachment loss (\n p<\/jats:italic>\n = 0.401). A higher bleeding points index was recorded amongst healthy individuals as compared to the Psoriasis group, the difference being statistically significant (\n p<\/jats:italic>\n = 0.001). The mean number of teeth were more in the Psoriasis group as compared to the healthy group (p=0.034). IL 33 levels were also not significantly different (\n p<\/jats:italic>\n = 0.491).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Contrary to currently available evidence in literature, the study did not find a statistically significant association between Psoriasis and Inflammatory Periodontal Disease.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/idoj.idoj_445_20","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T05:48:18Z","timestamp":1613972898000},"page":"281-284","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Psoriasis and Periodontitis"],"prefix":"10.4103","volume":"12","author":[{"given":"Shipra","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Dogra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gurparkash Singh","family":"Chahal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savita","family":"Prashar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angadveer Pal","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mili","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-9-20240828","first-page":"1","article-title":"Periodontal aspects for psoriasis: A systematic review","volume":"3","author":"Monson","year":"2016","journal-title":"J Clin Res"},{"key":"R3-9-20240828","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/j.1346-8138.1997.tb02779.x","article-title":"Natural history of psoriasis: A study from the Indian subcontinent","volume":"24","author":"Kaur","year":"1997","journal-title":"J Dermatol"},{"key":"R4-9-20240828","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.3109\/00016357.2013.766360","article-title":"Periodontal disease and risk of psoriasis among nurses in the United States","volume":"71","author":"Nakib","year":"2013","journal-title":"Acta Odontol Scand"},{"key":"R5-9-20240828","first-page":"342410","article-title":"Physiopathological Role of IL-33: New Highlights in Bone Biology and a Proposed Role in Periodontal Disease","volume":"2014","author":"Da Luz","year":"2014","journal-title":"Mediators of Inflammation"},{"key":"R6-9-20240828","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1111\/j.1365-2133.2012.11126.x","article-title":"The effects of chronic periodontitis and its treatment on the subsequent risk of psoriasis","volume":"167","author":"Keller","year":"2012","journal-title":"Br J Dermatol"},{"key":"R7-9-20240828","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1080\/09546630500375841","article-title":"Effectiveness of climatotherapy at the Dead Sea for psoriasis vulgaris: A community-oriented study introducing the \u2018Beer Sheva Psoriasis Severity Score\u2019","volume":"16","author":"Cohen","year":"2005","journal-title":"J Dermatolog Treat"},{"key":"R8-9-20240828","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3109\/00016356408993968","article-title":"Periodontal disease in pregnancy. 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Correlation between oral hygiene and periodontal condition","volume":"22","author":"Silness","year":"1964","journal-title":"Acta Odontol Scand"},{"key":"R9-9-20240828","first-page":"7","article-title":"The simplified oral hygiene index","volume":"68","author":"Greene","year":"1964","journal-title":"JADA"},{"key":"R10-9-20240828","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1600-0757.2006.00179.x","article-title":"Toll-like receptors and their role in periodontal health and disease","volume":"43","author":"Mahanonda","year":"2007","journal-title":"Periodontol 2000"},{"key":"R11-9-20240828","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1902\/jop.2011.110239","article-title":"Interleukin-33 levels in gingival crevicular fluid, saliva, or plasma do not differentiate chronic periodontitis","volume":"83","author":"Buduneli","year":"2012","journal-title":"J Periodontol"},{"key":"R12-9-20240828","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/jre.12078","article-title":"Gingival crevicular fluid levels of interferon- gamma, but not interleukin-4 or -33 or thymic stromal lymphopoietin, are increased in inflamed sites in patients with periodontal disease","volume":"49","author":"Papathanasiou","year":"2014","journal-title":"J Periodontal Res"},{"key":"R13-9-20240828","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.archoralbio.2014.08.021","article-title":"Gingival cre- vicular fluid interleukin-36beta (-1F8), interleukin-36gamma (-1F9) and interleukin-33 (-1F11) levels in different periodontal disease","volume":"60","author":"Kursunlu","year":"2015","journal-title":"Arch Oral Biol"},{"key":"R14-9-20240828","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1128\/IAI.00043-13","article-title":"Porphyromonas gingivalis infection-associated periodontal bone resorp- tion is dependent on receptor activator of NF-kappaB ligand","volume":"81","author":"Han","year":"2013","journal-title":"Infect Immun"},{"key":"R15-9-20240828","doi-asserted-by":"crossref","first-page":"4448","DOI":"10.1073\/pnas.1000803107","article-title":"IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skin","volume":"107","author":"Theoharides","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"R16-9-20240828","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1038\/jid.2012.185","article-title":"Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes","volume":"132","author":"Meephansan","year":"2012","journal-title":"J Invest Dermatol"},{"key":"R17-9-20240828","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1002\/eji.201041360","article-title":"IL-33 induces skin inflammation with mast cell and neutrophil activation","volume":"41","author":"Hueber","year":"2011","journal-title":"Eur J Immunol"},{"key":"R18-9-20240828","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jdermsci.2013.04.014","article-title":"Expression of IL-33 in the epidermis: The mechanism of induction by IL-17","volume":"71","author":"Meephansan","year":"2013","journal-title":"J Dermatol Sci"}],"container-title":["Indian Dermatology Online Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/idoj.IDOJ_445_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:40:42Z","timestamp":1787845242000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/idoj.IDOJ_445_20"}},"subtitle":["Exploring an association or lack thereof"],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/idoj.idoj_445_20","relation":{},"ISSN":["2229-5178"],"issn-type":[{"value":"2229-5178","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}