{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:03:15Z","timestamp":1787169795957,"version":"build-2736575974"},"reference-count":89,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Granulomatous dermatitis (GD) is one of the commonest tissue reaction patterns encountered in dermatopathology practice. Granulomatous inflammation in the skin can be seen in a wide range of conditions, thus, granulomatous dermatitis always poses significant challenge even to the astute dermatologists and dermatopathologists. Broadly, granulomatous dermatitis is divided into two groups\u2014infectious and non-infectious, the prevalence of both highly variable and show overlapping pathology. However, there are subtle histological clues, which when combined with clinical features, help to narrow down the differential diagnosis. Thus, a good Clinicopathological correlation (CPC) along with histochemical stains, culture and ancillary techniques including molecular studies are required for arriving at a definite diagnosis. In this review, we shall discuss the histological clues to diagnose non-infectious granulomatous dermatitis (NIGD) and their differential diagnoses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/idoj.idoj_662_20","type":"journal-article","created":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T09:21:26Z","timestamp":1637054486000},"page":"515-528","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":17,"title":["Non-Infectious Granulomatous Dermatoses"],"prefix":"10.4103","volume":"12","author":[{"given":"Debajyoti","family":"Chatterjee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajsmita","family":"Bhattacharjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uma Nahar","family":"Saikia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20240828","doi-asserted-by":"crossref","first-page":"217","DOI":"10.4103\/0019-5154.27993","article-title":"Infectious granulomatous dermatitis: A clinico pathological study","volume":"51","author":"Bal","year":"2006","journal-title":"Indian J Dermatol"},{"key":"R2-4-20240828","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/DAD.0000000000001441","article-title":"Granulomatous skin diseases in a tertiary care Portuguese hospital: A 10-year retrospective study","volume":"42","author":"Queiros","year":"2020","journal-title":"Am J Dermatopathol"},{"key":"R3-4-20240828","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.0303-6987.2004.00194.x","article-title":"Collagenolytic (necrobiotic) granulomas: Part 1--The \u201cblue\u201d granulomas","volume":"31","author":"Lynch","year":"2004","journal-title":"J Cutan Pathol"},{"key":"R4-4-20240828","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.0303-6987.2004.00208.x","article-title":"Collagenolytic (necrobiotic) granulomas: Part II--The \u2018red\u2019 granulomas","volume":"31","author":"Lynch","year":"2004","journal-title":"J Cutan Pathol"},{"key":"R5-4-20240828","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/j.1600-0560.2006.00566.x","article-title":"Non-infectious granulomatous dermatitis: A clinicopathological study","volume":"33","author":"Mohan","year":"2006","journal-title":"J Cutan Pathol"},{"key":"R6-4-20240828","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1111\/j.1600-0560.2006.00563.x","article-title":"Clinical spectrum and histological analysis of 32 cases of specific cutaneous sarcoidosis","volume":"33","author":"Mangas","year":"2006","journal-title":"J Cutan Pathol"},{"key":"R7-4-20240828","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.1468-3083.2012.04473.x","article-title":"Cutaneous sarcoidosis in southern Taiwan: Clinicopathologic study of a series with high proportions of lesions confined to the face and angiolupoid variant","volume":"27","author":"Wu","year":"2013","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"R8-4-20240828","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.0303-6987.2004.00157.x","article-title":"The histologic spectrum of cutaneous sarcoidosis: A study of twenty-eight cases","volume":"31","author":"Ball","year":"2004","journal-title":"J Cutan Pathol"},{"key":"R9-4-20240828","first-page":"427","article-title":"Foreign bodies in granulomatous cutaneous lesions of patients with systemic sarcoidosis","volume":"137","author":"Marcoval","year":"2001","journal-title":"Arch Dermatol"},{"key":"R10-4-20240828","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/00000372-200010000-00004","article-title":"Foreign bodies in sarcoidosis","volume":"22","author":"Kim","year":"2000","journal-title":"Am J Dermatopathol"},{"key":"R11-4-20240828","first-page":"485","article-title":"The presence of foreign bodies does not exclude the diagnosis of sarcoidosis","volume":"137","author":"Callen","year":"2001","journal-title":"Arch Dermatol"},{"key":"R12-4-20240828","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1111\/j.1365-2133.2005.06815.x","article-title":"Subcutaneous sarcoidosis--Clinicopathological study of 10 cases","volume":"153","author":"Marcoval","year":"2005","journal-title":"Br J Dermatol"},{"key":"R13-4-20240828","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1365-2230.1993.tb00972.x","article-title":"Subcutaneous sarcoidosis","volume":"18","author":"Higgins","year":"1993","journal-title":"Clin Exp Dermatol"},{"key":"R14-4-20240828","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0002-9343(63)90165-7","article-title":"Manifestations of sarcoidosis. 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