{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:32:15Z","timestamp":1787070735395,"version":"build-2736575974"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pigmented epithelioid melanocytoma (PEM) is a rare and diagnostically challenging skin neoplasm. Differentiating this lesion from melanoma is challenging due to overlapping clinical, histopathological, and immunohistochemical features. Some PEMs have a benign course, while others may be associated with more aggressive behaviour and have potential for local recurrence or distant metastasis. So, careful evaluation and follow-up are crucial for individuals with a diagnosis of PEM. This case study focuses on a 42-year-old woman with a gradually enlarging, dark, pigmented gluteal lesion. Histopathological analysis following complete excision showed nodular proliferation of spindled and epithelioid melanocytes in the dermis, extending into subcutaneous fat. Cellular atypia or mitotic figures were absent, confirming the diagnosis as PEM. This case underscores the intricate balance between monitoring and intervention in complex dermatological cases, shedding light on diagnostic challenges and ultimately striving for improved patient care.<\/jats:p>","DOI":"10.4103\/idoj.idoj_726_23","type":"journal-article","created":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T09:01:19Z","timestamp":1720429279000},"page":"996-999","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Unraveling Complexity: Delving into a Novel Pigmented Epithelioid Melanocytoma Case"],"prefix":"10.4103","volume":"15","author":[{"given":"Vijaya V.","family":"Mysorekar","sequence":"first","affiliation":[{"name":"Department of Pathology, Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Ramanagara, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nidha","family":"Gaffoor","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Ramanagara, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B N","family":"Divyashree","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Ramanagara, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S Sharath Chandra","family":"Tejas","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research, Dayananda Sagar University, Ramanagara, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,7,5]]},"reference":[{"key":"R1-20251023","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2013-008865","article-title":"Pigmented epithelioid melanocytoma: A new concept encompassing animal-type melanoma and epithelioid blue nevus","author":"Gavriilidis","year":"2013","journal-title":"BMJ Case Rep 2013"},{"key":"R2-20251023","first-page":"1290","article-title":"Pigmented epithelioid melanocytomas and their mimics;Focus on their novel molecular findings","volume":"10","author":"Bayraktar","year":"2021","journal-title":"Biology (Basel)"},{"key":"R3-20251023","doi-asserted-by":"crossref","first-page":"e2020070","DOI":"10.5826\/dpc.1004a70","article-title":"A case of a pigmented epithelioid melanocytoma on a mucosal site","volume":"10","author":"Ramondetta","year":"2020","journal-title":"Dermatol Pract Concept"},{"key":"R4-20251023","first-page":"1217","article-title":"Metastatic pigmented epithelioid melanocytoma in a 7-year-old female","volume":"19","author":"Thielmann","year":"2021","journal-title":"J Dtsch Dermatol Ges"},{"key":"R5-20251023","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.dsi.2011.09.011","article-title":"Pigmented epithelioid melanocytoma: Report of a case and review of 173 cases in the literature","volume":"30","author":"Cheng","year":"2012","journal-title":"Dermatol Sin"}],"container-title":["Indian Dermatology Online Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/idoj.idoj_726_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:35:44Z","timestamp":1787067344000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/idoj.idoj_726_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,5]]},"references-count":5,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/idoj.idoj_726_23","relation":{},"ISSN":["2229-5178","2249-5673"],"issn-type":[{"value":"2229-5178","type":"print"},{"value":"2249-5673","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,5]]},"assertion":[{"value":"2023-09-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-26","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}