{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:37:05Z","timestamp":1786649825812,"version":"build-2736575974"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aims:<\/jats:title>\n                    <jats:p>Surgical excision of tongue cancer lesions can cause haemodynamic surges, requiring high opioid doses. This study evaluated the efficacy of lingual nerve block in preventing haemodynamic surges and reducing opioid and volatile anaesthetic requirements during tongue cancer resection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      This randomised controlled trial included 132 patients aged 18\u201360 years with American Society of Anesthesiologists (ASA) physical status I and II undergoing wide local excision of unilateral tongue cancer. Group B (n = 67) received a lingual nerve block with 2 mL of 2% lignocaine, while Group A (n = 65) received 2 mL of saline. Maximum mean arterial pressure (MAP), heart rate, fentanyl usage, and minimum alveolar concentration (MAC) during resection were compared. Wilcoxon\u2019s rank sum and Student\u2019s\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test were used to compare non-parametric and parametric variables, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Maximum MAP was lower in Group B [99.61 (standard deviation, SD: 13.72) (95% confidence interval, CI: 96.33, 102.90) mmHg] than in Group A [107.85 (SD: 12.71) (95% CI: 104.76, 110.94) mmHg] (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001). The median rise in MAP from baseline was lower in Group B (10 mmHg, interquartile range, IQR: 3.5\u201316) compared to Group A (24 mmHg, IQR: 17\u201334) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Maximum heart rate was similar between groups, but the rise in heart rate was lower in Group B [7.46 (SD: 7.72) (95% CI: 5.61, 9.31) beats per minute (bpm)] than in Group A [12.83 (SD: 9.33) (95% CI: 10.56, 15.10) bpm] (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001). Group B required significantly less fentanyl (0 \u00b5g, IQR: 0\u20130) than Group A (80 \u00b5g, IQR: 50\u2013150) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Maximum and mean MAC were lower in Group B (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.019, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Lingual nerve block effectively controls haemodynamic surges during tongue cancer resection, with reduced opioid and anaesthetic requirements.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ija.ija_1002_24","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T09:01:00Z","timestamp":1741856460000},"page":"358-364","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of lingual nerve block in preventing haemodynamic response due to surgical stimulation in patients undergoing tongue cancer resections: A randomised controlled trial"],"prefix":"10.4103","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3302-5224","authenticated-orcid":false,"given":"Shalini","family":"Chaudhuri","sequence":"first","affiliation":[{"name":"Department of Anaesthesia, Critical Care and Pain, Mahamana Pandit Madan Mohan Malaviya Cancer Centre and Homi Bhabha Cancer Hospital, Homi Bhabha National Institute (HBNI), Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1956-1931","authenticated-orcid":false,"given":"Sandipan","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Critical Care and Pain, Mahamana Pandit Madan Mohan Malaviya Cancer Centre and Homi Bhabha Cancer Hospital, Homi Bhabha National Institute (HBNI), Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0564-6084","authenticated-orcid":false,"given":"Syed S.","family":"Hussain","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Critical Care and Pain, Mahamana Pandit Madan Mohan Malaviya Cancer Centre and Homi Bhabha Cancer Hospital, Homi Bhabha National Institute (HBNI), Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5483-5917","authenticated-orcid":false,"given":"Monotosh","family":"Pramanik","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Critical Care and Pain, Mahamana Pandit Madan Mohan Malaviya Cancer Centre and Homi Bhabha Cancer Hospital, Homi Bhabha National Institute (HBNI), Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2961-5473","authenticated-orcid":false,"given":"Uddalak","family":"Chattopadhyay","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Critical Care and Pain, Mahamana Pandit Madan Mohan Malaviya Cancer Centre and Homi Bhabha Cancer Hospital, Homi Bhabha National Institute (HBNI), Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9398-519X","authenticated-orcid":false,"given":"Nikhil K.","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Critical Care and Pain, Mahamana Pandit Madan Mohan Malaviya Cancer Centre and Homi Bhabha Cancer Hospital, Homi Bhabha National Institute (HBNI), Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"R1-20260422","doi-asserted-by":"crossref","first-page":"880","DOI":"10.4103\/ija.ija_313_23","article-title":"Analgesic efficacy of the inferior alveolar nerve block for maxillofacial cancer surgery under general anaesthesia \u2013 A randomised controlled study","volume":"67","author":"Shetmahajan","year":"2023","journal-title":"Indian J Anaesth"},{"key":"R2-20260422","first-page":"100535","article-title":"A randomized control trial to study the effect of bilateral Gow-gates block on visibility of surgical field and hemodynamic response in patients with carcinoma tongue","volume":"31","author":"Brahmanandan","year":"2022","journal-title":"Cancer Treat Res Commun"},{"issue":"Suppl 1","key":"R3-20260422","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/anae.15243","article-title":"The role of regional anaesthesia in the emerging subspecialty of onco-anaesthesia: A state-of-the-art review","volume":"76","author":"Dockrell","year":"2021","journal-title":"Anaesthesia"},{"key":"R4-20260422","doi-asserted-by":"crossref","first-page":"250","DOI":"10.4103\/ams.ams_65_17","article-title":"Efficacy of exclusive lingual nerve block versus conventional inferior alveolar nerve block in achieving lingual soft-tissue anesthesia","volume":"7","author":"Balasubramanian","year":"2017","journal-title":"Ann Maxillofac Surg"}],"container-title":["Indian Journal of Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ija.ija_1002_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:58:50Z","timestamp":1786647530000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ija.ija_1002_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,13]]},"references-count":4,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ija.ija_1002_24","relation":{},"ISSN":["0019-5049","0976-2817"],"issn-type":[{"value":"0019-5049","type":"print"},{"value":"0976-2817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,13]]},"assertion":[{"value":"2024-09-29","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}