{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:23:42Z","timestamp":1787840622111,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aims:<\/jats:title>\n                    <jats:p>Intrathecal morphine (ITM) or erector spinae plane (ESP) block reduces postsurgical pain in patients who underwent kidney transplantation surgeries. We aimed to compare the effectiveness of both modalities in terms of duration and quality of postoperative analgesia along with postoperative fentanyl consumption.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a randomised study and analysed 60 patients posted for elective live-related kidney transplantation surgery. They were randomised into two groups. Group M patients received ITM, whereas Group E patients received ESP block. We standardised the postoperative analgesia for both groups with intravenous fentanyl-based patient-controlled analgesia. The primary outcome was to compare the quality of analgesia using the numerical rating scale score between the groups. The secondary outcome was to observe the effect of both modalities on the duration of analgesia, postoperative fentanyl consumption, rescue analgesics requirement, catheter-related bladder discomfort and any complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We found significantly lower pain scores at rest and while coughing in Group M at all time intervals, except at 24 h while coughing. The mean time to first analgesia requirement was significantly longer in Group M than in Group E (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.002). No significant difference was found in postoperative consumption of total fentanyl (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.065) and rescue analgesia in both groups. In Group M, there was significantly more nausea, vomiting and pruritus (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>ITM provides long-lasting postoperative analgesia at the cost of higher side effects than ESP block.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ija.ija_271_24","type":"journal-article","created":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T08:03:55Z","timestamp":1717661035000},"page":"644-650","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Comparison of intrathecal morphine versus erector spinae block for postoperative analgesia in patients with end-stage kidney disease undergoing kidney transplantation: A randomised clinical study"],"prefix":"10.4103","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7056-996X","authenticated-orcid":false,"given":"Saurabh","family":"Mittal","sequence":"first","affiliation":[{"name":"Department of Organ Transplant Anaesthesia and Critical Care, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8634-989X","authenticated-orcid":false,"given":"Medha","family":"Bhardwaj","sequence":"additional","affiliation":[{"name":"Department of Neuro-Anaesthesia, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2918-3210","authenticated-orcid":false,"given":"Praveenkumar","family":"Shekhrajka","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Critical Care, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3318-3726","authenticated-orcid":false,"given":"Vipin Kumar","family":"Goyal","sequence":"additional","affiliation":[{"name":"Department of Organ Transplant Anaesthesia and Critical Care, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,6,7]]},"reference":[{"key":"R1-20260505","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.3390\/jcm11123435","article-title":"Anaesthetic approach to enhanced recovery after surgery for kidney transplantation: A narrative review","volume":"11","author":"Jaszczuk","year":"2022","journal-title":"J Clin Med"},{"key":"R2-20260505","doi-asserted-by":"crossref","first-page":"402","DOI":"10.4103\/ijot.ijot_49_23","article-title":"Acute pain management after kidney transplantation: A current review of literature","volume":"17","author":"Goyal","year":"2023","journal-title":"Indian J Transpl"},{"key":"R3-20260505","first-page":"e39151","article-title":"Continuous erector spinae plane analgesia in kidney transplant recipients: A quality improvement project","volume":"15","author":"Vishwanath","year":"2023","journal-title":"Cureus"},{"key":"R4-20260505","doi-asserted-by":"crossref","first-page":"83","DOI":"10.6002\/ect.MESOT2021.O36","article-title":"Erector spinae plane block for postoperative analgesia after kidney transplant","volume":"20","author":"Sharipova","year":"2022","journal-title":"Exp Clin Transplant"},{"key":"R5-20260505","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1093\/pm\/pny221","article-title":"Erector spinae plane block in pain management after kidney transplantation","volume":"20","author":"Temirov","year":"2019","journal-title":"Pain 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trial","volume":"44","author":"Kang","year":"2019","journal-title":"Reg Anesth Pain Med"},{"key":"R12-20260505","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1080\/11101849.2023.2277094","article-title":"Ultrasound guided erector spinae plane block versus intrathecal morphine for analgesia following major hepatopancreaticobiliary surgery","volume":"39","author":"Sayed","year":"2023","journal-title":"Egypt J Anaesth"},{"key":"R13-20260505","doi-asserted-by":"crossref","first-page":"110479","DOI":"10.1016\/j.jclinane.2021.110479","article-title":"Bilateral continuous erector spinae plane block using a programmed intermittent bolus regimen versus intrathecal morphine for postoperative analgesia in living donor laparoscopic hepatectomy: A randomized controlled trial","volume":"75","author":"Kang","year":"2021","journal-title":"J Clin Anesth"},{"key":"R14-20260505","doi-asserted-by":"crossref","first-page":"e14558","DOI":"10.1111\/petr.14558","article-title":"Outcomes in pediatric liver transplant recipients receiving bilateral continuous erector spinae plane blocks","volume":"27","author":"Dewey","year":"2023","journal-title":"Pediatr Transplant"},{"key":"R15-20260505","doi-asserted-by":"crossref","first-page":"597","DOI":"10.2147\/JPR.S242568","article-title":"Analgesic Efficacy of Erector Spinae Plane Block Compared with Intrathecal Morphine After Elective Cesarean Section: A Prospective Randomized Controlled Study","volume":"13","author":"Hamed","year":"2020","journal-title":"J Pain Res"},{"key":"R16-20260505","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1177\/0300060515595650","article-title":"Efficacy of intrathecal morphine for postoperative pain management following open nephrectomy","volume":"44","author":"Kim","year":"2016","journal-title":"J Int Med Res"},{"key":"R17-20260505","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.3390\/jcm11082136","article-title":"Intrathecal morphine, transversus abdominis plane block, and tramadol Infusion for catheter-related bladder discomfort in patients undergoing robot-assisted laparoscopic prostatectomy (TORNADO): A pilot prospective controlled study","volume":"11","author":"Russo","year":"2022","journal-title":"J Clin Med"}],"container-title":["Indian Journal of 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