{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:58:33Z","timestamp":1787169513468,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10]]},"abstract":"\n Background and Aims:<\/jats:title>\n \n Ventilator-associated pneumonia (VAP) is the most common healthcare-associated infection in adult critical care units. The reason behind the different levels of severity and the outcome in different individuals is not established yet.Co-morbidities and age may be a valid reason.In an attempt to find out the reason behind the different levels of severity of VAP in different individuals, we conducted a studywith the primary objective being to assess the quantitative correlation between the colony forming units (CFU) of\n Acinetobacter baumannii<\/jats:italic>\n in the endotracheal tube aspirate and the Clinical Pulmonary Infection Score (CPIS) in mechanically ventilated patients without co-morbidities. The secondary objective was to see whether the severity of VAP depends on the number of CFU(>105\/ml).\n <\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n This observational study was conducted in a 27-bedded intensive care unit of a tertiary care hospital in northern India. Endotracheal tube aspirate was collected from patients with suspected VAP.A total of 81 patients without any prior co-morbidity and having\n Acinetobacter baumannii<\/jats:italic>\n in their endotracheal tube aspirate were included in the study group. Quantification of\n Acinetobacter baumannii<\/jats:italic>\n was done by counting CFU.The CPIS was calculated for all\n Acinetobacter baumannii<\/jats:italic>\n positive patients. Correlation between CFU of\n Acinetobacter baumannii<\/jats:italic>\n and CPIS was assessed using Spearman\u2019s Rho correlation coefficient.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Among 81 patients having\n Acinetobacter baumannii<\/jats:italic>\n infection, only 61.9% had a CPIS >4. There was an insignificant correlation between the quantity of CFUs of\n Acinetobacter baumannii<\/jats:italic>\n and CPIS (\n P<\/jats:italic>\n value = 0.784).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Number of CFU >105\/ml in an endotracheal tube aspirate culture bears no relation to the severity of VAP as predicted by the CPIS.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ija.ija_649_21","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T02:02:33Z","timestamp":1634781753000},"page":"S163-S167","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Quantitative correlation of colony forming units of Acinetobacter baumannii obtained from endotracheal tube aspirate culture with clinical pulmonary infection score"],"prefix":"10.4103","volume":"65","author":[{"given":"Rakesh C.","family":"Chaurasia","sequence":"first","affiliation":[{"name":"Department of Anaesthesia, IMS, BHU, Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bikram K.","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, IMS, BHU, Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghanshyam","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, IMS, BHU, Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun R.","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, IMS, BHU, Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuhina","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Department of Microbiology, IMS, BHU, Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swati","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Microbiology, IMS, BHU, Varanasi, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,10,28]]},"reference":[{"key":"-20240902","doi-asserted-by":"crossref","first-page":"3854","DOI":"10.1378\/chest.128.6.3854","article-title":"Epidemiology and outcomes of health-care-associated pneumonia:Results from a large US database of culture-positive pneumonia","volume":"128","author":"Kollef","year":"2005","journal-title":"Chest"},{"key":"-20240902","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.jiph.2019.09.015","article-title":"The incidence of ventilator-associated pneumonia (VAP) in a tertiary-care center:Comparison between pre- and post-VAP prevention bundle","volume":"13","author":"Osman","year":"2020","journal-title":"J Infect Public 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