{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:36:25Z","timestamp":1786739785362,"version":"build-2736575974"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aims:<\/jats:title>\n                    <jats:p>Intraoperative hypotension (IOH) is inevitable during moderate-to-high-risk surgeries. In kidney transplantation, intraoperative hypotensive events can badly affect postoperative graft and patient outcomes. Traditionally, central venous pressure monitoring has been regarded as a fundamental aspect of intraoperative haemodynamic management during kidney transplantation. Recently, the focus has changed by including newer haemodynamic tools (FloTrac, Hemosphere, etc.) to reduce intraoperative hypotensive events and postoperative complications. The primary objective was to record IOH (incidence, duration, and severity).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This study was done retrospectively to observe the effect of haemodynamic monitoring on IOH. Recipients with dilated cardiomyopathy (DCMP) aged 18\u201360 years who underwent kidney transplantation from June 2022 to May 2024 were included and had cardiac output measured by FloTrac or Hemosphere. The primary outcome was to record the time-weighted average (TWA) of IOH. Secondary outcomes were to record the average number of hypotensive events per patient and the average duration of each hypotensive event.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Twenty-eight patients with DCMP were included. The primary outcome of TWA of the area under threshold (MAP &lt; 65 mmHg) per patient was more in patients in the FloTrac group in comparison to the Acumen group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.613). Secondary outcomes, namely the incidence of hypotensive events per patient and total time of hypotension, were significantly higher in the FloTrac group as compared to the Acumen group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Hypotension prediction index (HPI) provides superior intraoperative haemodynamic management in kidney transplant recipients with DCMP in terms of reduced duration, incidence, and severity of IOH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ija.ija_927_24","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T10:00:29Z","timestamp":1744797629000},"page":"496-501","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Impact of FloTrac versus hypotension prediction index (HPI)-guided haemodynamic management on intraoperative hypotension in kidney transplantation: A retrospective observational study"],"prefix":"10.4103","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3318-3726","authenticated-orcid":false,"given":"Vipin Kumar","family":"Goyal","sequence":"first","affiliation":[{"name":"Department of Organ Transplant Anaesthesia and Critical Care, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2918-3210","authenticated-orcid":false,"given":"Praveenkumar","family":"Shekhrajka","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Critical Care, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7056-996X","authenticated-orcid":false,"given":"Saurabh","family":"Mittal","sequence":"additional","affiliation":[{"name":"Department of Organ Transplant Anaesthesia and Critical Care, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8634-989X","authenticated-orcid":false,"given":"Medha","family":"Bhardwaj","sequence":"additional","affiliation":[{"name":"Neuro-Anaesthesia, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,4,16]]},"reference":[{"key":"R1-20250416","doi-asserted-by":"crossref","first-page":"109961","DOI":"10.1016\/j.jclinane.2020.109961","article-title":"The incidence of intraoperative hypotension in moderate to high-risk patients undergoing non-cardiac surgery: A retrospective multicentre observational analysis","volume":"66","author":"Shah","year":"2020","journal-title":"J Clin Anesth"},{"key":"R2-20250416","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.bja.2023.08.026","article-title":"Intraoperative hypotension and postoperative outcomes: A meta-analysis of randomised trials","volume":"131","author":"D\u2019Amico","year":"2023","journal-title":"Br J Anaesth"},{"key":"R3-20250416","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1378\/chest.07-2331","article-title":"Does central venous pressure predict fluid responsiveness? 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versus central venous pressure-guided fluid therapy on renal allograft outcome in patients undergoing living donor renal transplant surgery: A comparative study","volume":"29","author":"Srivastava","year":"2015","journal-title":"J Anesth"},{"key":"R13-20250416","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1001\/jama.2020.0592","article-title":"Effect of a machine learning-derived early warning system for intraoperative hypotension vs standard care on depth and duration of intraoperative hypotension during elective noncardiac surgery: The HYPE randomized clinical trial","volume":"323","author":"Wijnberge","year":"2020","journal-title":"JAMA"},{"key":"R14-20250416","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1007\/s10877-023-01017-1","article-title":"Hypotension prediction index guided goal directed therapy and the amount of hypotension during major gynaecologic oncologic surgery: A randomized controlled clinical 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