{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:51:40Z","timestamp":1786737100668,"version":"build-2736575974"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J App Basic Med Res"],"published-print":{"date-parts":[[2020]]},"DOI":"10.4103\/ijabmr.ijabmr_179_19","type":"journal-article","created":{"date-parts":[[2020,10,4]],"date-time":"2020-10-04T10:15:51Z","timestamp":1601806551000},"page":"234","source":"Crossref","is-referenced-by-count":2,"title":["Molecular detection of fusion oncogenes in zambian patients with acute lymphoblastic leukemia"],"prefix":"10.4103","volume":"10","author":[{"given":"Pauline","family":"Okuku","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Kwenda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mulemba","family":"Samutela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panji","family":"Nkhoma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamakwa","family":"Mantina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/2229-516X.297249-1","doi-asserted-by":"crossref","unstructured":"Nasedkina T, Zasedatelev A, Samochatova E, Guseva N, Gra O, Yatsenko Y. Diagnostics of Molecular Markers in Childhood Acute Leukaemia Using Biochips. Intech Open Access Publisher; 2011. Accessed from: https:\/\/www.intechopen.com\/ books\/acute-leukemia-the-scientist-s-perspective-and-challenge\/ diagnostics-of-molecular-markers-in-childhood-acute-leukaemia-using-biochips. [Last accessed on 2020 Jul 08].","DOI":"10.5772\/23653"},{"key":"key-10.4103\/2229-516X.297249-2","first-page":"53","volume-title":"A systematic literature review of the clinical and epidemiological burden of acute lymphoblastic leukaemia (ALL)","author":"Redaelli","year":"2005","journal-title":"Eur J Cancer Care (Engl)"},{"key":"key-10.4103\/2229-516X.297249-3","first-page":"f1660","volume-title":"Leukaemia update.Part 1: Diagnosis and management","author":"Grigoropoulos","year":"2013","journal-title":"BMJ"},{"key":"key-10.4103\/2229-516X.297249-4","first-page":"631","volume-title":"Acute lymphoblastic leukemia","author":"Harrison","year":"2011","journal-title":"Clin Lab Med"},{"key":"key-10.4103\/2229-516X.297249-5","first-page":"123","volume-title":"The clinical relevance of chromosomal and genomic abnormalities in B-cell precursor acute lymphoblastic leukaemia","author":"Moorman","year":"2012","journal-title":"Blood Rev"},{"key":"key-10.4103\/2229-516X.297249-6","first-page":"131","volume-title":"New immune strategies for the treatment of acute lymphoblastic leukemia: Antibodies and chimeric antigen receptors","author":"Advani","year":"2013","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"key-10.4103\/2229-516X.297249-7","first-page":"84","volume-title":"Coexistence of iAMP21 and ETV6-RUNX1 fusion in an adolescent with B cell acute lymphoblastic leukemia: Literature review of six additional cases","author":"Gu","year":"2016","journal-title":"Mol Cytogenet"},{"key":"key-10.4103\/2229-516X.297249-8","first-page":"5312","volume-title":"Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic\/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia","author":"Harvey","year":"2010","journal-title":"Blood"},{"key":"key-10.4103\/2229-516X.297249-9","first-page":"237","volume-title":"Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia","author":"Yang","year":"2011","journal-title":"Nat Genet"},{"key":"key-10.4103\/2229-516X.297249-10","first-page":"937","volume-title":"The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes","author":"Vardiman","year":"2009","journal-title":"Blood"},{"key":"key-10.4103\/2229-516X.297249-11","first-page":"551","volume-title":"Biology, risk stratification, and therapy of pediatric acute leukemias: An update","author":"Pui","year":"2011","journal-title":"J Clin Oncol"},{"key":"key-10.4103\/2229-516X.297249-12","first-page":"349","volume-title":"RT-PCR and real-time PCR analysis of E2A-PBX1, TEL-AML1, mBCR-ABL and MLL-AF4 fusion gene transcripts in de novo B-lineage acute lymphoblastic leukaemia patients in south India","author":"Sudhakar","year":"2011","journal-title":"J Genet"},{"key":"key-10.4103\/2229-516X.297249-13","first-page":"453","volume-title":"Clinical characteristics of acute lymphoblastic leukemia in male and female patients: A retrospective analysis of 705 patients","author":"Li","year":"2015","journal-title":"Oncol Lett"},{"key":"key-10.4103\/2229-516X.297249-14","unstructured":"Howlader N, Noone AM, Krapcho M, Garshell J, Neyman N, Altekruse SF, et al, editors. SEER Cancer Statistics Review, 1975-2010. National Cancer Institute; Bethesda, MD. Available from: http:\/\/seer.cancer.gov\/csr\/1975_2010\/, based on November 2012 SEER data submission, posted to the SEER web site, April 2013."},{"key":"key-10.4103\/2229-516X.297249-15","first-page":"3","volume-title":"Childhood acute lymphoblastic leukemia: Indian experience","author":"Bhutani","year":"2004","journal-title":"Indian J Med Paediatr Oncol","ISSN":"https:\/\/id.crossref.org\/issn\/0971-5851","issn-type":"print"},{"key":"key-10.4103\/2229-516X.297249-16","first-page":"223","volume-title":"Acute lymphoblastic leukemia in children and adolescents: Prognostic factors and analysis of survival","author":"Lustosa","year":"2015","journal-title":"Rev Bras Hematol Hemoter"},{"key":"key-10.4103\/2229-516X.297249-17","first-page":"49","volume-title":"The detection and significance of chromosomal abnormalities in childhood acute lymphoblastic leukaemia","author":"Harrison","year":"2001","journal-title":"Blood Rev"},{"key":"key-10.4103\/2229-516X.297249-18","first-page":"1520","volume-title":"Molecular diagnostics","author":"Braziel","year":"2003","journal-title":"Hematol Am Soc Hematol Educ Program"},{"key":"key-10.4103\/2229-516X.297249-19","first-page":"930","volume-title":"Karyotyping, FISH, and PCR in acute lymphoblastic leukemia: Competing or complementary diagnostics?","author":"Olde","year":"2009","journal-title":"J Pediatr Hematol Oncol"},{"key":"key-10.4103\/2229-516X.297249-20","first-page":"175","volume-title":"Molecular genetics of acute lymphoblastic leukemia","author":"Teitell","year":"2009","journal-title":"Annu Rev Pathol"},{"key":"key-10.4103\/2229-516X.297249-21","first-page":"227","volume-title":"Frequency of the ETV6-RUNX1, BCR-ABL1, TCF3-PBX1, and MLL-AFF1 fusion genes in Guatemalan pediatric acute lymphoblastic leukemia patients and their ethnic associations","author":"Carranza","year":"2013","journal-title":"Cancer Genet"},{"key":"key-10.4103\/2229-516X.297249-22","first-page":"1541","volume-title":"Acute Lymphoblastic Leukemia in Children","author":"Hunger","year":"2015","journal-title":"N Engl J Med"},{"key":"key-10.4103\/2229-516X.297249-23","first-page":"210560","volume-title":"Prevalence of gene rearrangements in Mexican children with acute lymphoblastic leukemia: A population study-report from the Mexican Interinstitutional Group for the identification of the causes of childhood leukemia","author":"Bekker-M\u00e9ndez","year":"2014","journal-title":"Biomed Res Int"},{"key":"key-10.4103\/2229-516X.297249-24","first-page":"1518","volume-title":"BCR-ABL, ETV6-RUNX1 and E2A-PBX1: Prevalence of the most common acute lymphoblastic leukemia fusion genes in Mexican patients","author":"Jim\u00e9nez-Morales","year":"2008","journal-title":"Leuk Res"},{"key":"key-10.4103\/2229-516X.297249-25","first-page":"4","volume-title":"A (1;19) translocation involving TCF3-PBX1 fusion within the context of a hyperdiploid karyotype in adult B-ALL: A case report and review of the literature","author":"Tirado","year":"2015","journal-title":"Biomark Res"},{"key":"key-10.4103\/2229-516X.297249-26","first-page":"3343","volume-title":"The molecular biology of chronic myeloid leukemia","author":"Deininger","year":"2000","journal-title":"Blood"},{"key":"key-10.4103\/2229-516X.297249-27","first-page":"4171","volume-title":"Serial measurement of BCR-ABL transcripts in the peripheral blood aftet allogeneic stem cell transplantation for chronic myeloid leukemia: An attempt to define patients who may not require further therapy","author":"Kaeda","year":"2006","journal-title":"Blood"},{"key":"key-10.4103\/2229-516X.297249-28","first-page":"2147","volume-title":"Adults with acute lymphoblastic leukemia and translocation (1;19) abnormality have a favorable outcome with hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone alternating with methotrexate and high-dose cytarabine chemotherapy","author":"Garg","year":"2009","journal-title":"Cancer"},{"key":"key-10.4103\/2229-516X.297249-29","first-page":"295","volume-title":"Tyrosine kinase inhibitors in BCR-ABL positive acute lymphoblastic leukemia","author":"Leoni","year":"2015","journal-title":"Haematologica"},{"key":"key-10.4103\/2229-516X.297249-30","first-page":"1943","volume-title":"Acute lymphoblastic leukaemia","author":"Inaba","year":"2013","journal-title":"Lancet"},{"key":"key-10.4103\/2229-516X.297249-31","first-page":"574","volume-title":"Multiplex reverse transcription-polymerase chain reaction for simultaneous screening of 29 translocations and chromosomal aberrations in acute leukemia","author":"Pallisgaard","year":"1998","journal-title":"Blood"},{"key":"key-10.4103\/2229-516X.297249-32","first-page":"73","volume-title":"TEL\/AML-1 fusion gene.its frequency and prognostic significance in childhood acute lymphoblastic leukemia","author":"Jamil","year":"2000","journal-title":"Cancer Genet Cytogenet"},{"key":"key-10.4103\/2229-516X.297249-33","first-page":"639","volume-title":"Origins of chromosome translocations in childhood leukaemia","author":"Greaves","year":"2003","journal-title":"Nat Rev Cancer"},{"key":"key-10.4103\/2229-516X.297249-34","first-page":"429","volume-title":"Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: Results from the UK Medical Research Council ALL97\/99 randomised trial","author":"Moorman","year":"2010","journal-title":"Lancet Oncol"}],"container-title":["International Journal of Applied and Basic Medical Research"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T18:50:14Z","timestamp":1786733414000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijabmr.IJABMR_179_19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020]]}},"alternative-id":["297249"],"URL":"https:\/\/doi.org\/10.4103\/ijabmr.ijabmr_179_19","relation":{},"ISSN":["2229-516X"],"issn-type":[{"value":"2229-516X","type":"print"}],"subject":[],"published":{"date-parts":[[2020]]}}}