{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:19:30Z","timestamp":1787775570665,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Schwannoma, a benign tumor, arise from schwann cells of myelin sheath; occur anywhere in the body but commonly occur on flexor aspect of extremities. Nasal septum being the rarer site. We report a case of nasal septum schwannoma in an 18-year-old female presented with intermittent epistaxis and progressively increasing nasal obstruction for 2-year duration. The differential diagnosis of juvenile angiofibroma, pyogenic granuloma, and pleomorphic adenoma was made and complete surgical excision was done. Histopathological examination revealed ciliated stratified columnar epithelium, underlying tumor area with two distinct patterns, mainly hypercellular and few hypocellular areas. The cells have spindle shaped pointed basophilic nuclei with abundant eosinophilic cytoplasm. Overall feature was suggestive of nasal septum schwannoma. For confirmation, immunohistochemical staining with S-100 was done and tumor was found positive. Herein, we report the clinicopathological features of nasal septum schwannoma in an 18-year-old female.<\/jats:p>","DOI":"10.4103\/ijabmr.ijabmr_354_22","type":"journal-article","created":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T08:08:17Z","timestamp":1725264497000},"page":"284-287","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Schwannoma of the Nasal Septum: A Rare Clinicopathological Case Report in an 18-Year-Old Female"],"prefix":"10.4103","volume":"12","author":[{"given":"Nupur","family":"Kaushik","sequence":"first","affiliation":[{"name":"Department of Pathology, S.N. Medical College, Agra, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa","family":"Rani","sequence":"additional","affiliation":[{"name":"Department of Pathology, S.N. Medical College, Agra, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lalit","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pathology, S.N. Medical College, Agra, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akhil Pratap","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of ENT, S.N. Medical College, Agra, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,12,19]]},"reference":[{"key":"R1-20240902","first-page":"1","article-title":"Nasal cavity schwannoma \u2013A case report and review of the literature","author":"Liao","year":"2021","journal-title":"Ear Nose Throat J"},{"key":"R2-20240902","doi-asserted-by":"crossref","first-page":"781","DOI":"10.18203\/issn.2454-5929.ijohns20191750","article-title":"Schwannoma nasal cavity:A clinicopathological case report","volume":"5","author":"Seles","year":"2019","journal-title":"Int J Otorhinolaryngol Head Neck Surg"},{"key":"R3-20240902","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.18203\/issn.2454-5929.ijohns20174348","article-title":"A large sinonasal schwannoma:A rare entity","volume":"3","author":"Singh","year":"2017","journal-title":"Int J Otorhinolaryngol Head Neck Surg"},{"key":"R4-20240902","doi-asserted-by":"crossref","first-page":"41","DOI":"10.5152\/tao.2017.1929","article-title":"Septal schwannoma of the nose:A rare case","volume":"55","author":"Gupta","year":"2017","journal-title":"Turk Arch Otorhinolaryngol"},{"key":"R5-20240902","doi-asserted-by":"crossref","first-page":"257","DOI":"10.21474\/IJAR01\/10150","article-title":"Schwannoma of the nasal septum:A rare case","volume":"7","author":"En-Nouali","year":"2019","journal-title":"Int J Adv Res"},{"key":"R6-20240902","first-page":"E4","article-title":"Schwannoma of the nasal septum:An unusual finding","volume":"93","author":"Dhingra","year":"2014","journal-title":"Ear Nose Throat J"},{"key":"R7-20240902","first-page":"46","article-title":"Sinonasal schwannoma \u2013A clinicopathological analysis of five rare cases","volume":"44","author":"Mey","year":"2006","journal-title":"Rhinology"},{"key":"R8-20240902","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4103\/1858-5000.157509","article-title":"Schwannoma of the nasal cavity:A case report and a review","volume":"10","author":"Mosalleum","year":"2015","journal-title":"Sudan Med Monit"},{"key":"R9-20240902","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ejenta.2012.08.002","article-title":"Schwannoma of nasal septum:A rare case report with literature review","volume":"13","author":"Mitra","year":"2012","journal-title":"Egypt J Ear Nose Throat Allied Sci"},{"key":"R10-20240902","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ejenta.2016.06.001","article-title":"Schwannoma of the nasal septum","volume":"17","author":"Karatas","year":"2016","journal-title":"Egypt J Ear Nose Throat Allied Sci"},{"key":"R11-20240902","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1272\/jnms.80.300","article-title":"Solitary nasal schwannoma:Usefulness of CD34 and calretinin staining for distinction from histological mimics","volume":"80","author":"Ohashi","year":"2013","journal-title":"J Nippon Med Sch"}],"container-title":["International Journal of Applied &amp; Basic Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijabmr.ijabmr_354_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:32:32Z","timestamp":1787772752000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijabmr.ijabmr_354_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijabmr.ijabmr_354_22","relation":{},"ISSN":["2229-516X","2248-9606"],"issn-type":[{"value":"2229-516X","type":"print"},{"value":"2248-9606","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"2022-06-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}