{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:02:42Z","timestamp":1787169762680,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Carbamazepine is a commonly used drug in psychiatric settings used for indications such as partial seizures, generalized tonic-clonic seizures, mixed seizure patterns, pain associated with trigeminal neuralgia, acute manic, and mixed manic states. However, this drug comes with its own series of adverse effects such as nausea, vomiting, diarrhea, dizziness, hyponatremia, headaches, and dry mouth. One serious side effect which is rarely documented includes \u201ccarbamazepine-induced pancytopenia.\u201d In this case report, we wish to highlight a known case of schizophrenia, who was taking tablet carbamazepine as adjunctive treatment and subsequently developed pancytopenia. On removing the offending agent, her counts gradually returned to normal. By reporting this case, we wish to emphasize regarding the importance of regular monitoring of complete blood count, which often gets neglected. Furthermore, psychoeducating patients regarding regular blood monitoring and the importance of adherence holds considerable importance in enhancing their compliance. By ensuring such simple preventive measures, such serious and unusual side effects may be averted through early detection of warning signs.<\/jats:p>","DOI":"10.4103\/ijabmr.ijabmr_530_22","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T08:13:47Z","timestamp":1680164027000},"page":"44-46","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Pancytopenia in Carbamazepine Therapy: A Rare and Serious Entity with Simple Prevention"],"prefix":"10.4103","volume":"13","author":[{"given":"Akansha","family":"Bhardwaj","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Hamdard Institute of Medical Sciences and Research, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Prakash","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Hamdard Institute of Medical Sciences and Research, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimple","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Hamdard Institute of Medical Sciences and Research, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimmi","family":"Jose","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Hamdard Institute of Medical Sciences and Research, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,3,27]]},"reference":[{"key":"R3-20240902","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4103\/0974-2727.78555","article-title":"Pancytopenia:A clinico hematological study","volume":"3","author":"Gayathri","year":"2011","journal-title":"J Lab Physicians"},{"key":"R4-20240902","first-page":"1108","article-title":"The common causes leading to pancytopenia in patients presenting to tertiary care hospital","volume":"29","author":"Das Makheja","year":"2013","journal-title":"Pak J Med Sci"},{"key":"R5-20240902","first-page":"97","article-title":"Carbamazepine-induced pancytopenia:A rare entity","volume":"3","author":"Mathur","year":"2018","journal-title":"J Mahatma Gandhi Univ Med Sci Technol"},{"key":"R6-20240902","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1600-0404.1990.tb00949.x","article-title":"Epidemiology of adverse reactions to carbamazepine as seen in a spontaneous reporting system","volume":"81","author":"Askmark","year":"1990","journal-title":"Acta Neurol Scand"},{"key":"R8-20240902","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/hup.990","article-title":"Comparison of carbamazepine and lithium in treatment of bipolar disorder:A systematic review of randomized controlled trials","volume":"24","author":"Ceron-Litvoc","year":"2009","journal-title":"Hum Psychopharmacol"},{"key":"R9-20240902","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/ana.410110312","article-title":"Carbamazepine and hematological monitoring","volume":"11","author":"Hart","year":"1982","journal-title":"Ann Neurol"},{"key":"R10-20240902","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1007\/s10072-014-1701-0","article-title":"Anticonvulsant drugs and hematological disease","volume":"35","author":"Verrotti","year":"2014","journal-title":"Neurol Sci"},{"key":"R13-20240902","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1111\/j.1538-7836.2009.03360.x","article-title":"Drug-induced immune thrombocytopenia:Pathogenesis, diagnosis, and management","volume":"7","author":"Aster","year":"2009","journal-title":"J Thromb Haemost"},{"key":"R14-20240902","first-page":"611","article-title":"Carbamazipine induced pancytopenia in patient with schizophrenia","volume":"9","author":"Prajapati","year":"2021","journal-title":"Int J Res Educ Sci Methods"},{"key":"R15-20240902","first-page":"173","article-title":"Transient pancytopenia and SIADH associated with administration of carbamazepine","volume":"25","author":"Jeong","year":"2001","journal-title":"J Korean Acad Rehabil Med"}],"container-title":["International Journal of Applied &amp; Basic Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijabmr.ijabmr_530_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:11:49Z","timestamp":1787166709000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijabmr.ijabmr_530_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ijabmr.ijabmr_530_22","relation":{},"ISSN":["2229-516X","2248-9606"],"issn-type":[{"value":"2229-516X","type":"print"},{"value":"2248-9606","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"2022-09-26","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-05","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}