{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:23:06Z","timestamp":1787757786437,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>Mal de Meleda (MDM) is a rare autosomal recessive type of palmoplantar keratoderma that is characterized by transgradient keratoderma with scleroatrophy, pseudoainhum around the fingers, and perioral erythema. Its features may also include lichenoid lesions, brachydactyly, and nail dystrophy. The disease has high morbidity and significantly impairs quality of life. Here, we describe two sisters with typical clinical presentations of MDM and a history of consanguinity between the parents.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijabmr.ijabmr_812_21","type":"journal-article","created":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T08:26:43Z","timestamp":1652084803000},"page":"151-154","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Two Sisters with Mal de Meleda"],"prefix":"10.4103","volume":"12","author":[{"given":"Dua","family":"Cebeci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seide","family":"Karasel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6rg\u00fcn","family":"Bayraktaroglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-16-20240902","doi-asserted-by":"crossref","first-page":"206803","DOI":"10.1155\/2013\/206803","article-title":"Particular Mal de Meleda phenotypes in Tunisia and mutations founder effect in the Mediterranean region","volume":"2013","author":"Bchetnia","year":"2013","journal-title":"Biomed Res Int"},{"key":"R3-16-20240902","first-page":"196","article-title":"Mal de Meleda type of keratoderma","volume":"47","author":"Thappa","year":"2002","journal-title":"Indian J Dermatol"},{"key":"R4-16-20240902","doi-asserted-by":"crossref","first-page":"390","DOI":"10.4103\/0019-5154.100497","article-title":"Mal de meleda with lip involvement:A report of two cases","volume":"57","author":"Nath","year":"2012","journal-title":"Indian J Dermatol"},{"key":"R5-16-20240902","doi-asserted-by":"crossref","first-page":"e7972","DOI":"10.1097\/MD.0000000000007972","article-title":"A Mal de Meleda patient with severe flexion contractures of hands and feet:A case report in West China","volume":"96","author":"Pan","year":"2017","journal-title":"Medicine (Baltimore"},{"key":"R6-16-20240902","doi-asserted-by":"crossref","first-page":"S100","DOI":"10.1590\/S0365-05962011000700026","article-title":"Mal de Meleda:A report of two cases of familial occurrence","volume":"86","author":"Silva","year":"2011","journal-title":"An Bras Dermatol"},{"key":"R7-16-20240902","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1111\/bjd.13868","article-title":"Heterogeneity in the properties of mutant secreted lymphocyte antigen 6\/urokinase receptor-related protein 1 (SLURP1) in Mal de Meleda","volume":"173","author":"Adeyo","year":"2015","journal-title":"Br J Dermatol"},{"key":"R8-16-20240902","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1590\/S0365-05962003000300007","article-title":"Vohwinkel\u00b4s mutilating keratoderma:Report of three familial cases","volume":"78","author":"Cavalcante","year":"2003","journal-title":"An Bras Dermatol"},{"key":"R9-16-20240902","first-page":"249","article-title":"Palmoplantar keratosis with periodontal disease (Papillon-L\u00e8fevre)","volume":"45","author":"Proen\u00e7a","year":"1970","journal-title":"An Bras Dermatol"},{"key":"R10-16-20240902","doi-asserted-by":"crossref","first-page":"bcr2012006443","DOI":"10.1136\/bcr-2012-006443","article-title":"Diffuse epidermolytic palmoplantar keratoderma (Unna-Thost-)","volume":"2012","author":"Hinterberger","year":"2012","journal-title":"BMJ Case Rep"},{"key":"R11-16-20240902","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1365-2133.1992.tb08060.x","article-title":"Acitretin in the treatment of mal de Meleda","volume":"127","author":"van","year":"1992","journal-title":"Br J Dermatol"},{"key":"R12-16-20240902","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/jso.10317","article-title":"Melanoma Cooperative Group. Malignant melanoma developing in an area of hereditary palmoplantar keratoderma (Mal de Meleda)","volume":"84","author":"Mozzillo","year":"2003","journal-title":"J Surg Oncol"}],"container-title":["International Journal of Applied &amp; Basic Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijabmr.ijabmr_812_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:53:33Z","timestamp":1787756013000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijabmr.ijabmr_812_21"}},"subtitle":["Case Series Report"],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/ijabmr.ijabmr_812_21","relation":{},"ISSN":["2229-516X"],"issn-type":[{"value":"2229-516X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]}}}