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Due to unresectable disease, she was given a trial of immunotherapy followed by conventional chemotherapy. She showed partial response on interim assessment, but progressed soon after the completion of six cycles and succumbed to her rapidly progressive illness within nine months of diagnosis. This report discusses the diagnostic and therapeutic challenges faced while managing this disease of aggressive tumor biology.<\/jats:p>","DOI":"10.4103\/ijc.ijc_1010_21","type":"journal-article","created":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T22:00:05Z","timestamp":1711144805000},"page":"131-134","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Epithelioid angiosarcoma of the pericardium: Case report of the challenges in the management of a rare malignancy with poor prognosis"],"prefix":"10.4103","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8308-8690","authenticated-orcid":false,"given":"Bhupesh","family":"Guleria","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, Malignant Diseases Treatment Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9608-7152","authenticated-orcid":false,"given":"Prerna","family":"Guleria","sequence":"additional","affiliation":[{"name":"Department of Pathology, Command Hospital (Southern Command), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azhar","family":"Husain","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Command Hospital (Southern Command), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anurag","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Command Hospital (Southern Command), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes","family":"Raphael","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Malignant Diseases Treatment Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasanta","family":"Sengupta","sequence":"additional","affiliation":[{"name":"Department of Pathology, Command Hospital (Southern Command), Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,3,22]]},"reference":[{"key":"R2-20240828","first-page":"2641976","article-title":"Primary cardiac epithelioid angiosarcoma in a Latin American patient:Case report and literature review","author":"Morgenstern-Kaplan","year":"2019","journal-title":"Case Rep Oncol Med"},{"key":"R3-20240828","first-page":"802","article-title":"Primary Angiosarcoma of the Pericardium. 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