{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:39:09Z","timestamp":1787071149113,"version":"build-2736575974"},"reference-count":37,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec>\n                    <jats:title>CONTEXT:<\/jats:title>\n                    <jats:p>To evaluate the quality of life (QOL) outcome measures in disease-free survivors of pathological T1\/T2 tongue cancers and to compare QOL in patients treated with only surgery and with adjuvant treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>SETTINGS AND DESIGN:<\/jats:title>\n                    <jats:p>Cross-sectional survey.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PATIENTS AND METHODS:<\/jats:title>\n                    <jats:p>All pathological T1\/T2 anterior tongue cancer cases with follow-up from January 2011 till December 2015, who had locoregionally controlled disease with a minimum disease-free survival period of 1 year, were included in the study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      A total of 36 patients, 28 are males and 8 are females with an age range of 24\u201366 years (median age of 43) were enrolled in the study. The patients were divided into two groups with (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 26) and without adjuvant postoperative radiotherapy (RT) (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 10) and the University of Washington-QOL questionnaire version 4 for physical and social domains, global questions and three important domains were analyzed. On the physical and social domain scores, the surgery-alone group outscored the combined modality group on all scales and the differences were statistically significant for specific physical domains such as saliva (0.0001), taste (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0001), chewing (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0004), swallowing (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0026), and social domains such as mood (0.0001), pain (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0001), and shoulder function (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.0061). The overall global QOL scores were also better for the surgical group compared with group which received adjuvant RT but was not statistically significant. All patients chose saliva as their top priority domain in the group which received radiation, and 60% chose \u201cswallowing ability\u201d as the preferred top priority domain in the only surgical group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>Although locoregional control and disease-free survival are the major treatment-related endpoints for cancer management, QOL outcome measures have to assess to determine the impact of a treatment modality on patients well-being and for better rehabilitation of cancer-free patients.<\/jats:p>\n                  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