{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:33:56Z","timestamp":1787762036135,"version":"build-2784847793"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Music and medicine can be used in patients with cancer as a palliative complementary therapy. It is aimed to show the effect of music therapy performed on anxiety, depression, and chemotherapy-related nausea\/vomiting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A total of 62 patients with colon cancer who previously experienced grade 1 or 2 chemotherapy-related nausea and vomiting were divided into two groups as intervention and control group based on the addition of music and medicine to infusion chemotherapies and 1:1 randomized. The groups were compared in terms of the effect of music and medicine on anxiety, depression, heart rate, blood pressure, and chemotherapy-related nausea-vomiting. Statistical analysis was done using SPSS Statistics for Windows, Version 19.0. A value of\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05 was found statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The patients were evaluated in terms of study variables at the beginning and after the completion of a chemotherapy session. As a result, there was a significant decrease in systolic blood pressure (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.042), diastolic blood pressure (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.44), heart rate (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.046), state and trait sections of the state-trait anxiety inventory scores (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.047 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.046, respectively), as well as a significant decrease in anxiety degree (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.036) and a significant improvement in chemotherapy-related nausea (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.021) and vomiting (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.038) experience in the intervention group. However, no significant effect of music and medicine on depression was detected (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.218).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Although it has not been shown to have an effect on depression, it was concluded that music and medicine with classical music integrated into the chemotherapy session can reduce the degree of nausea\/vomiting and anxiety levels.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijc.ijc_387_20","type":"journal-article","created":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T04:02:02Z","timestamp":1688443322000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Can music and medicine be effective on anxiety, depression and chemotherapy-related nausea and vomiting? (PEGASUS study)"],"prefix":"10.4103","author":[{"given":"Ozgur","family":"Tanriverdi","sequence":"first","affiliation":[{"name":"Department of Medical Oncology and Molecular Biology and Genetics, Mugla Sitki Kocman University, Mugla, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Turan","family":"Karaoglu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma Nil","family":"Aydemir","sequence":"additional","affiliation":[{"name":"Department of Violin, Mugla Fine Arts High School, Mugla, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,6,30]]},"container-title":["Indian Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijc.IJC_387_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:12:54Z","timestamp":1787760774000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijc.IJC_387_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4103\/ijc.ijc_387_20","relation":{},"ISSN":["0019-509X","1998-4774"],"issn-type":[{"value":"0019-509X","type":"print"},{"value":"1998-4774","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,30]]},"assertion":[{"value":"2020-04-24","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}