{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:26:05Z","timestamp":1787772365804,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Extragonadal germ cell tumors (GCTs) are a rare group of neoplasms that account for 1%\u20135% of all GCTs. These tumors can present with an unpredictable behavior and clinical manifestations depending on different factors such as histological subtype, anatomical site, and clinical stage. We report the case of a 43-year-old male patient with a primitive extragonadal seminoma located in the paravertebral dorsal region, an extremely rare site. He presented to our emergency department with a 3-month history of back pain and a 1-week history of fever of unknown origin. Imaging techniques revealed a solid tissue arising from the vertebral bodies of D9\u2013D11 and extending in the paravertebral space. After a bone marrow biopsy and exclusion of testicular seminoma, he was diagnosed with primitive extragonadal seminoma. The patient underwent five cycles of chemotherapy, and the follow-up CT examinations showed a reduction of the mass initially till a complete remission with no evidence of recurrence.<\/jats:p>","DOI":"10.4103\/ijc.ijc_880_21","type":"journal-article","created":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T01:03:40Z","timestamp":1670807020000},"page":"124-127","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Extragonadal germ cell tumor: A rare case in dorsal region"],"prefix":"10.4103","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2573-9509","authenticated-orcid":false,"given":"Maria Teresa","family":"Paparella","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, 71121 Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4172-5126","authenticated-orcid":false,"given":"Laura","family":"Eusebi","sequence":"additional","affiliation":[{"name":"Radiology Unit, \u201cCarlo Urbani\u201d Hospital, Jesi, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5198-8387","authenticated-orcid":false,"given":"Gaia","family":"Goteri","sequence":"additional","affiliation":[{"name":"Anatomic Pathology Unit, Department of Biomedical Sciences and Public Health, Polytechnic Marche University, Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9228-0913","authenticated-orcid":false,"given":"Francesco","family":"Bartelli","sequence":"additional","affiliation":[{"name":"Radiology Unit, \u201cCarlo Urbani\u201d Hospital, Jesi, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4325-8330","authenticated-orcid":false,"given":"Giuseppe","family":"Guglielmi","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, 71121 Foggia, Italy"},{"name":"Radiology Unit, Barletta University Campus UNIFG, \u201cDimiccoli\u201d Hospital, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,1,10]]},"reference":[{"key":"R1-20240828","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1097\/PAP.0b013e31803240e6","article-title":"Extragonadal germ cell tumors:A review with emphasis on pathologic features, clinical prognostic variables, and differential diagnostic considerations","volume":"14","author":"McKenney","year":"2007","journal-title":"Adv Anat Pathol"},{"key":"R2-20240828","first-page":"5650","article-title":"Extragonadal malignant germ cell tumors:A clinicopathological and immunohistochemical analysis of 48 cases at a single Chinese institution","volume":"8","author":"Gao","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"R3-20240828","doi-asserted-by":"crossref","first-page":"W274","DOI":"10.2214\/AJR.09.4103","article-title":"Adult extragonadal germ cell tumors","volume":"195","author":"Shinagare","year":"2010","journal-title":"AJR Am J Roentgenol"},{"issue":"(Suppl 4)","key":"R4-20240828","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1093\/annonc\/mdf669","article-title":"Extragonadal germ cell tumors","volume":"13","author":"Schmoll","year":"2002","journal-title":"Ann Oncol"},{"key":"R5-20240828","doi-asserted-by":"crossref","first-page":"8","DOI":"10.21037\/amj.2020.01.01","article-title":"Managing extragonadal germ cell tumors in male adults","volume":"5","author":"Chahoud","year":"2020","journal-title":"AME Med J"},{"key":"R6-20240828","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.2169\/internalmedicine.43.1099","article-title":"Extragonadal germ cell tumors","volume":"43","author":"Mizushima","year":"2004","journal-title":"Intern Med"},{"key":"R7-20240828","doi-asserted-by":"crossref","first-page":"6832","DOI":"10.1002\/cam4.2195","article-title":"Extragonadal germ cell tumors:Not just a matter of location. A review about clinical, molecular and pathological features","volume":"8","author":"Ronchi","year":"2019","journal-title":"Cancer Med"},{"key":"R8-20240828","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1200\/JCO.2002.07.062","article-title":"Extragonadal germ cell tumors of the mediastinum and retroperitoneum:Results from an international analysis","volume":"20","author":"Bokemeyer","year":"2002","journal-title":"J Clin Oncol"},{"key":"R9-20240828","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.eururo.2011.05.038","article-title":"EAU guidelines on testicular cancer:2011 update","volume":"60","author":"Albers","year":"2011","journal-title":"Eur Urol"},{"key":"R10-20240828","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/CCO.0b013e32835f085d","article-title":"Extragonadal germ cell tumors:Clinical presentation and management","volume":"25","author":"Albany","year":"2013","journal-title":"Curr Opin Oncol"}],"container-title":["Indian Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijc.ijc_880_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:41:34Z","timestamp":1787769694000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijc.ijc_880_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,10]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijc.ijc_880_21","relation":{},"ISSN":["0019-509X","1998-4774"],"issn-type":[{"value":"0019-509X","type":"print"},{"value":"1998-4774","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,10]]},"assertion":[{"value":"2021-07-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}