{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:26:16Z","timestamp":1787772376990,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Few studies have shown an association between adult lichen planus and dyslipidemia, but none has shown an association with the pediatric population. We planned to study the association between pediatric lichen planus and metabolic syndrome (MS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>This is a single-centre, cross-sectional, case-control study from July 2018 to December 2019 at a tertiary care institute. Twenty children in the age group of 6\u201316 years, diagnosed as cases of childhood\/adolescent lichen planus, and 40 age- and sex-matched controls were included in this study and evaluated for metabolic syndrome.<\/jats:p>\n                    <jats:p>Patients' anthropometry including weight, height, waist circumference, and body mass index (BMI) was recorded. Blood samples were sent for the measurement of fasting plasma glucose, high-density lipoprotein (HDL), low-density lipoprotein (LDL) cholesterol, and triglyceride levels.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean HDL was found to be significantly lower in children with lichen planus compared to children without lichen planus (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.012), although there was no statistically significant difference in the frequency of patients having deranged HDL levels between the groups (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.326). Children with lichen planus had a higher prevalence of central obesity, but the difference was not statistically significant (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.101). There was no significant difference between mean BMI, hypertension, triglyceride, LDL, and fasting blood sugar values between the groups. Using the logistic regression analysis model, it was found that the strongest independent variable that impacts the occurrence of lichen planus was an HDL value less than 40 mg\/dl (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.017; OR 1.02 to 1.29).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Relevance:<\/jats:title>\n                    <jats:p>This study shows an association between paediatric lichen planus and dyslipidemia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijd.ijd_100_22","type":"journal-article","created":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T12:14:59Z","timestamp":1716984899000},"page":"531-534","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Cross-sectional Study Shows an Association between Paediatric Lichen Planus and Dyslipidemia"],"prefix":"10.4103","volume":"67","author":[{"given":"Rahul","family":"Mahajan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh","family":"Raj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipankar","family":"De","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev","family":"Handa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-8-20240829","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/0190-9622(91)70241-S","article-title":"Lichen planus","volume":"25","author":"Boyd","year":"1991","journal-title":"J Am Acad Dermatol"},{"key":"R2-8-20240829","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1525-1470.2001.018001001.x","article-title":"Childhood lichen planus: A report of 23 cases","volume":"18","author":"Nanda","year":"2001","journal-title":"Pediatr Dermatol"},{"key":"R3-8-20240829","doi-asserted-by":"crossref","first-page":"742826","DOI":"10.1155\/2014\/742826","article-title":"Cutaneous and mucosal lichen planus: A comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis","volume":"2014","author":"Gorouhi","year":"2014","journal-title":"Scientific World Journal"},{"key":"R4-8-20240829","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.2337\/diab.37.12.1595","article-title":"Banting lecture 1988. 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