{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:34:11Z","timestamp":1790109251099,"version":"4.0.1"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Many studies have associated male androgenetic alopecia with the risk of cardiovascular disorders but very few studies have addressed this association in women with FPHL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This was a cross-sectional hospital-based study in which a total of 50 women (18-45 years) were recruited. The objective was to measure carotid intima-media thickness (CIMT) by doppler ultrasound, Body mass index (BMI), waist circumference, lipid profile, fasting blood sugar (FBS), insulin, testosterone, Sex hormone binding globulin (SHBG), hs-CRP, ESR and fibrinogen, in pre-menopausal women having FPHL and to correlate these parameters with severity of FPHL. The prevalence of Metabolic syndrome (MetS) and Insulin resistance were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Metabolic syndrome and insulin resistance were found in 12 (24%) and 17 (34%) cases respectively. Hypercholesterolemia, elevated LDL levels and hypertriglyceridemia, low HDL levels and hyperinsulinemia were found in 11 (22%), 31 (62%), 9 (18%), 17 (34%) and 7 (14%) cases respectively. 8 (16%) cases were diabetics. Elevated ESR, increased fibrinogen levels and elevated hs-CRP were found in 43 (86%), 10 (20%) and 21 (42%) cases respectively. CIMT was found to be within its normal range. Correlation of CIMT, anthropometric indices (BMI and WC), biochemical markers (serum cholesterol, triglycerides, FBS, and fibrinogen), and presence of metabolic syndrome with severity of FPHL in terms of Ludwig grade was found to be statistically significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The determination of metabolic syndrome, insulin resistance and acute phase reactants such as hs-CRP and fibrinogen may be useful screening methods to detect increased cardiovascular risk in women with FPHL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijd.ijd_104_23","type":"journal-article","created":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T07:01:12Z","timestamp":1709103672000},"page":"7-15","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Assessment of Cardiovascular Risk Factors in Women Having Female Pattern Hair Loss"],"prefix":"10.4103","volume":"69","author":[{"given":"Damini","family":"Verma","sequence":"first","affiliation":[{"name":"From the Department of Dermatology, Lady Hardinge Medical College, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vibhu","family":"Mendiratta","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, Lady Hardinge Medical College, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taru","family":"Garg","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, Lady Hardinge Medical College, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita","family":"Tripathi","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Lady Hardinge Medical College, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaili","family":"Tomer","sequence":"additional","affiliation":[{"name":"Department of Radiology, Lady Hardinge Medical College, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,2,27]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"767628","DOI":"10.1155\/2014\/767628","article-title":"The female pattern hair loss:Review of etiopathogenesis and diagnosis","volume":"2014","author":"Vujovic","year":"2014","journal-title":"Biomed Res Int"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"106","DOI":"10.5958\/2455-6769.2016.00008.9","article-title":"An epidemiological study of female pattern hair loss at a referral centre in South India","volume":"2","author":"Ravikiran","year":"2016","journal-title":"IP Indian J Clin Exp Dermatol"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"2","DOI":"10.5070\/D38525G87B","article-title":"Androgenetic alopecia and coronary artery disease in women","volume":"11","author":"Mansouri","year":"2005","journal-title":"Dermatol Online J"},{"key":"R4-20240829","first-page":"21","article-title":"The presence of insulin resistance and comparison of various insulin sensivity indices in women with androgenetic alopecia","volume":"17","author":"Ekmekci","year":"2007","journal-title":"Eur J Dermatol"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.jaad.2009.10.018","article-title":"Androgenetic alopecia and cardiovascular risk factors in men and women:A comparative study","volume":"63","author":"Arias-Santiago","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1111\/j.1365-2133.2012.10978.x","article-title":"Gender-specific association of androgenetic alopecia with metabolic syndrome in a middle-aged Korean population","volume":"167","author":"Yi","year":"2012","journal-title":"Br J Dermatol"},{"key":"R7-20240829","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1001\/jamadermatol.2013.130","article-title":"Association of androgenetic alopecia with mortality from diabetes mellitus and heart disease","volume":"149","author":"Su","year":"2013","journal-title":"JAMA Dermatol"},{"key":"R8-20240829","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1365-2133.1977.tb15179.x","article-title":"Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex","volume":"97","author":"Ludwig","year":"1977","journal-title":"Br J Dermatol"},{"key":"R9-20240829","doi-asserted-by":"crossref","first-page":"123","DOI":"10.4103\/0974-7753.58555","article-title":"Dermoscopy in female androgenic alopecia:Method standardization and diagnostic criteria","volume":"1","author":"Rakowska","year":"2009","journal-title":"Int J Trichology"},{"key":"R10-20240829","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/j.amjcard.2009.07.005","article-title":"Screening for subclinical coronary artery disease measuring carotid intima media thickness","volume":"104","author":"Nguyen-Thanh","year":"2009","journal-title":"Am J Cardiol"},{"key":"R11-20240829","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0140-6736(03)15268-3","article-title":"Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies","volume":"363","year":"2004","journal-title":"Lancet"},{"key":"R12-20240829","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1242\/dmm.001180","article-title":"A comprehensive definition for metabolic syndrome","volume":"2","author":"Huang","year":"2009","journal-title":"Dis Model Mech"},{"key":"R13-20240829","doi-asserted-by":"crossref","first-page":"14","DOI":"10.2337\/cd17-0119","article-title":"Standards of Medical Care in Diabetes-2018 Abridged for Primary Care Providers","volume":"36","year":"2018","journal-title":"Clin Diabetes"},{"key":"R15-20240829","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.jacc.2015.11.037","article-title":"A Test in Context:High-Sensitivity C-Reactive Protein","volume":"67","author":"Ridker","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"R16-20240829","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1472-6823-13-47","article-title":"Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population:Effect of gender and age:EPIRCE cross-sectional study","volume":"13","author":"Gayoso-Diz","year":"2013","journal-title":"BMC Endocr Disord"},{"key":"R17-20240829","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1111\/j.1365-2133.2010.09640.x","article-title":"Prevalence of androgenetic alopecia in China:A community-based study in six cities","volume":"162","author":"Wang","year":"2010","journal-title":"Br J Dermatol"},{"key":"R18-20240829","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1046\/j.1365-2133.2001.04289.x","article-title":"The prevalence and types of androgenetic alopecia in Korean men and women","volume":"145","author":"Paik","year":"2001","journal-title":"Br J Dermatol"},{"key":"R19-20240829","doi-asserted-by":"crossref","first-page":"42","DOI":"10.4103\/JCAS.JCAS_30_18","article-title":"Correlation between clinical features, biochemical parameters, and histopathological findings in women with patterned baldness:A study from North India","volume":"12","author":"Tandon","year":"2019","journal-title":"J Cutan Aesthet Surg"},{"key":"R20-20240829","doi-asserted-by":"crossref","first-page":"23","DOI":"10.4103\/0974-7753.96082","article-title":"Female pattern hair loss:Clinico-laboratory findings and trichoscopy depending on disease severity","volume":"4","author":"Zhang","year":"2012","journal-title":"Int J Trichology"},{"key":"R21-20240829","first-page":"762","article-title":"Clinicoepidemiological study of female pattern hair loss","volume":"3","author":"Okram","year":"2015","journal-title":"Int J Adv Res"},{"key":"R22-20240829","doi-asserted-by":"crossref","first-page":"196","DOI":"10.4103\/ijem.IJEM_650_17","article-title":"Association of Androgenetic alopecia with metabolic syndrome:A case-control study on 100 patients in a tertiary care hospital in South India","volume":"22","author":"Dharam Kumar","year":"2018","journal-title":"Indian J Endocrinol Metab"},{"key":"R23-20240829","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4103\/1110-6530.178459","article-title":"Risks for metabolic syndrome and cardiovascular diseases in both male and female patients with androgenetic alopecia","volume":"35","author":"Agamia","year":"2015","journal-title":"Egypt J Dermatol Venereol"},{"key":"R24-20240829","doi-asserted-by":"crossref","first-page":"287","DOI":"10.33549\/physiolres.930573","article-title":"What may be the markers of the male equivalent of polycystic ovary syndrome?","volume":"53","author":"Duskov\u00e1","year":"2004","journal-title":"Physiol Res"},{"key":"R25-20240829","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1111\/ijd.13303","article-title":"Association of metabolic syndrome with female pattern hair loss in women:A case-control study","volume":"55","author":"El Sayed","year":"2016","journal-title":"Int J Dermatol"},{"key":"R26-20240829","doi-asserted-by":"crossref","first-page":"2","DOI":"10.5070\/D38525G87B","article-title":"Androgenetic alopecia and coronary artery disease in women","volume":"11","author":"Mansouri","year":"2005","journal-title":"Dermatol Online J"},{"key":"R27-20240829","doi-asserted-by":"crossref","first-page":"227","DOI":"10.4103\/ijt.ijt_111_19","article-title":"A study of correlation of angiographic evaluation of coronary artery disease with androgenetic alopecia-tricoheart study","volume":"11","author":"Patil","year":"2019","journal-title":"Int J Trichology"},{"key":"R28-20240829","doi-asserted-by":"crossref","first-page":"626","DOI":"10.4103\/0378-6323.116732","article-title":"Female pattern hair loss","volume":"79","author":"Singal","year":"2013","journal-title":"Indian J Dermatol Venereol Leprol"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.ijd_104_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:23:23Z","timestamp":1787768603000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.ijd_104_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijd.ijd_104_23","relation":{},"ISSN":["0019-5154","1998-3611"],"issn-type":[{"value":"0019-5154","type":"print"},{"value":"1998-3611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2023-01-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}