{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:39:18Z","timestamp":1787071158893,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>A dermoscope is an office tool used in the diagnosis of various disorders. At present, studies on hypertrophic lichen planus (HLP) and prurigo nodularis (PN) are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims and Objectives:<\/jats:title>\n                    <jats:p>The aim of this study was to compare the dermoscopic features of HLP and PN and to determine the role of dermoscopy in the differential diagnosis of both the conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A cross-sectional study was undertaken. After clinical assessment and relevant investigations, dermoscopy was performed using DermLite DL3 dermoscope (\u00d710) followed by histopathology. Dermoscopic findings in cases of HLP and PN were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Thirty patients each with HLP and PN were included in the study. On dermoscopy, peripheral striations were the most common findings in both the conditions. Statistically significant features on intergroup comparison included blue\u2013gray globules (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001), comedo-like openings (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001), and follicular plugging (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001) in HLP and pearly white areas with white starburst pattern (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.028), red dots and globules (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001), glomerular vessels (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.003), crusting (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.002), and erosions (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001) in PN.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Dermoscopy is useful in differentiating HLP and PN. Blue-gray globules, comedo-like openings, and follicular plugging were specific for HLP. Pearly white areas with white starburst pattern and red dots and globules were the specific findings in PN.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijd.ijd_123_18","type":"journal-article","created":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T03:51:12Z","timestamp":1567482672000},"page":"341-345","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":20,"title":["Role of Dermoscopy in the Diagnosis of Hypertrophic Lichen Planus and Prurigo Nodularis"],"prefix":"10.4103","volume":"64","author":[{"given":"Bangaru","family":"Hanumaiah","sequence":"first","affiliation":[{"name":"From the Department of Skin and VD, Mysore Medical College and Research Institute, Mysore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joice Maria","family":"Joseph","sequence":"additional","affiliation":[{"name":"From the Department of Skin and VD, Mysore Medical College and Research Institute, Mysore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250921","doi-asserted-by":"crossref","first-page":"300","DOI":"10.4103\/0378-6323.16633","article-title":"Dermoscope","volume":"71","author":"Nischal","year":"2005","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"R4-20250921","first-page":"129","article-title":"A case of multiple tumors of the skin accompanied by intense pruritus","volume":"6","author":"Hardaway","year":"1880","journal-title":"Arch Dermatol"},{"key":"R7-20250921","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/1346-8138.12844","article-title":"Dermoscopy of prurigo nodularis","volume":"42","author":"Errichetti","year":"2015","journal-title":"J Dermatol"},{"key":"R8-20250921","doi-asserted-by":"crossref","first-page":"9","DOI":"10.5826\/dpc.0602a03","article-title":"Hypertrophic lichen planus versus prurigo nodularis: A dermoscopic perspective","volume":"6","author":"Ankad","year":"2016","journal-title":"Dermatol Pract Concept"},{"key":"R9-20250921","first-page":"64","article-title":"Dermoscopy of lichen planus hypertrophicus: A retrospective analysis","volume":"27","author":"Jha","year":"2017","journal-title":"J Pak Assoc Dermatol"},{"key":"R11-20250921","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1111\/j.1600-0560.2009.01484.x","article-title":"Prurigo nodularis: Systematic analysis of 58 histological criteria in 136 patients","volume":"37","author":"Weigelt","year":"2010","journal-title":"J Cutan Pathol"},{"key":"R12-20250921","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1001\/archderm.1991.01680100084009","article-title":"Lichen planus and malignancy. An epidemiologic study of 2071 patients and a review of the literature","volume":"127","author":"Sigurgeirsson","year":"1991","journal-title":"Arch Dermatol"},{"key":"R13-20250921","doi-asserted-by":"crossref","first-page":"54","DOI":"10.4103\/0378-6323.30658","article-title":"Squamous cell carcinoma in hypertrophic lichen planus","volume":"73","author":"Joshi","year":"2007","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"R14-20250921","doi-asserted-by":"crossref","first-page":"457","DOI":"10.4103\/0019-5154.164355","article-title":"Concurrent presentation of erythrodermic lichen planus and squamous cell carcinoma: Coincidence or malignant transformation?","volume":"60","author":"Ali","year":"2015","journal-title":"Indian J Dermatol"},{"key":"R15-20250921","doi-asserted-by":"crossref","first-page":"239","DOI":"10.4103\/0378-6323.174413","article-title":"Treatment of prurigo nodularis with dexamethasone-cyclophosphamide pulse therapy","volume":"82","author":"Gupta","year":"2016","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"R16-20250921","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1159\/000246715","article-title":"Prurigo nodularis consists of two distinct forms: Early-onset atopic and late-onset non-atopic","volume":"190","author":"Tanaka","year":"1995","journal-title":"Dermatology"},{"key":"R17-20250921","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1159\/000071785","article-title":"Dermoscopic features of plaque psoriasis and lichen planus: New observations","volume":"207","author":"V\u00e1zquez-L\u00f3pez","year":"2003","journal-title":"Dermatology"},{"key":"R19-20250921","first-page":"1","article-title":"Dermoscopy in hair disorders","volume":"7","author":"Tosti","year":"2010","journal-title":"J Egypt Women Dermatol Soc"},{"key":"R20-20250921","doi-asserted-by":"crossref","first-page":"651","DOI":"10.4103\/0378-6323.183636","article-title":"Relevance of trichoscopy in the differential diagnosis of alopecia: A cross-sectional study from North India","volume":"82","author":"Chiramel","year":"2016","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"R22-20250921","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jaad.2008.05.013","article-title":"Dermatoscopy aids in the diagnosis of the solitary red scaly patch or plaque-features distinguishing superficial basal cell carcinoma, intraepidermal carcinoma, and psoriasis","volume":"59","author":"Pan","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"R23-20250921","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1111\/j.1468-3083.2004.01008.x","article-title":"Dermoscopic observation of Bowen's disease","volume":"18","author":"Bugatti","year":"2004","journal-title":"J Eur Acad Dermatol Venereol"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.IJD_123_18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:42:21Z","timestamp":1787067741000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.IJD_123_18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.4103\/ijd.ijd_123_18","relation":{},"ISSN":["0019-5154","1998-3611"],"issn-type":[{"value":"0019-5154","type":"print"},{"value":"1998-3611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"2018-03-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}