{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:25:40Z","timestamp":1787765140953,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Histiocytic sarcoma (HS) is a rare malignant neoplasm of presumed hematopoietic origin, showing morphologic and immunophenotypic evidence of histiocytic differentiation. A 61-year-old woman presented with an abdominal mass. She had a history of HS in both adrenal glands. The tumour cells of the left adrenal gland were very large epithelioid cells with abundant eosinophilic cytoplasm and large, round-to-oval nuclei. Similarly, the cutaneous lesion of the skin was composed of polygonal cells with well-defined cell borders and high nuclear\/cytoplasm (N\/C) ratios. Immunohistochemically, both tumours were positive for histiocyte-associated antigens but negative for epithelial, melanocyte, lymphoid, dendritic, and Langerhansl nuclei. Similarly, the cutaneous lesion of the skin was composenose correctly. It is important to recognise the morphological features and immunohistochemical characteristics of metastatic cells in order to achieve accurate diagnoses.<\/jats:p>","DOI":"10.4103\/ijd.ijd_245_23","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T05:04:16Z","timestamp":1704776656000},"page":"682-685","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Metastatic Histiocytic Sarcoma with Secondary Involvement of the Skin: A Case Report"],"prefix":"10.4103","volume":"68","author":[{"given":"Hyun-Min","family":"Seo","sequence":"first","affiliation":[{"name":"From the Department of Dermatology, College of Medicine, Hanyang University, Hanyang University Guri Hospital, Gyeonggi-do, South Korea"},{"name":"Hanyang Institute of Bioscience and Biotechnology, Hanyang University, Seongdong-gu, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Hun","family":"Park","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, College of Medicine, Hanyang University, Hanyang University Guri Hospital, Gyeonggi-do, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seon Young","family":"Song","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, College of Medicine, Hanyang University, Hanyang University Hospital, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se Uk","family":"Oh","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, College of Medicine, Hanyang University, Hanyang University Guri Hospital, Gyeonggi-do, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se Kwang","family":"Park","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, College of Medicine, Hanyang University, Hanyang University Guri Hospital, Gyeonggi-do, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Soo","family":"Han","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, College of Medicine, Hanyang University, Hanyang University Guri Hospital, Gyeonggi-do, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joung Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, College of Medicine, Hanyang University, Hanyang University Guri Hospital, Gyeonggi-do, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,1,9]]},"reference":[{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/path.1711600105","article-title":"Malignant lymphomas of true histiocytic origin. A clinical, histological, immunophenotypic and genotypic study","volume":"160","author":"Ralfkiaer","year":"1990","journal-title":"J Pathol"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1097\/01.pas.0000131541.95394.23","article-title":"Extranodal histiocytic sarcoma: Clinicopathologic analysis of 14 cases of a rare epithelioid malignancy","volume":"28","author":"Hornick","year":"2004","journal-title":"Am J Surg Pathol"},{"key":"R4-20240829","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1097\/00000478-199811000-00009","article-title":"True histiocytic lymphoma: A morphologic, immunohistochemical, and molecular genetic study of 13 cases","volume":"22","author":"Copie-Bergman","year":"1998","journal-title":"Am J Surg Pathol"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/00000478-200302000-00017","article-title":"Histiocytic sarcoma involving the central nervous system: Clinical, immunohistochemical, and molecular genetic studies of a case with review of the literature","volume":"27","author":"Sun","year":"2003","journal-title":"Am J Surg Pathol"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1365-2559.2002.01418.x","article-title":"Tumours of histiocytes and accessory dendritic cells: An immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases","volume":"41","author":"Pileri","year":"2002","journal-title":"Histopathology"},{"key":"R7-20240829","doi-asserted-by":"crossref","first-page":"e49","DOI":"10.1200\/JCO.2011.38.8553","article-title":"Histiocytic sarcoma arising from clonally related mantle cell lymphoma","volume":"30","author":"Hure","year":"2012","journal-title":"J Clin Oncol"},{"key":"R8-20240829","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s12185-010-0704-8","article-title":"Aggressive sporadic histiocytic sarcoma with immunoglobulin heavy chain gene rearrangement and t(14;18)","volume":"92","author":"Hayase","year":"2010","journal-title":"Int J Hematol"},{"key":"R9-20240829","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/j.1440-1827.2011.02671.x","article-title":"Histiocytic sarcoma of the parotid gland region","volume":"61","author":"Akiba","year":"2011","journal-title":"Pathol Int"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.ijd_245_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:00:40Z","timestamp":1787763640000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.ijd_245_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ijd.ijd_245_23","relation":{},"ISSN":["0019-5154","1998-3611"],"issn-type":[{"value":"0019-5154","type":"print"},{"value":"1998-3611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"2023-03-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}