{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:26:06Z","timestamp":1787772366838,"version":"build-2784847793"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,9]]},"abstract":"\n Background:<\/jats:title>\n Acne vulgaris (AV) is a chronic inflammatory disorder. Intercellular adhesion molecule-1 (ICAM-1) is a vital adhesion molecule mediating cellular adhesion during the inflammatory process.<\/jats:p>\n <\/jats:sec>\n \n Aims and Objectives:<\/jats:title>\n To evaluate serum soluble intercellular adhesion molecule-1 (sICAM-1) level in AV patients as an attempt to elucidate its role in acne pathogenesis and to relate with studied clinical parameters.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n Serum sICAM-1 level was measured using ELISA technique in 60 patients and 60 controls.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Serum sICAM-1 level was significantly elevated in studied patients than controls (\n P<\/jats:italic>\n < 0.001). Additionally, its level increased significantly with increased acne severity (\n P<\/jats:italic>\n < 0.001) but not in patients with post acne scars (\n P<\/jats:italic>\n > 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Serum sICAM-1 could be a marker for acne etiopathogenesis. Furthermore, it might be considered as a predictor for disease severity.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/ijd.ijd_387_21","type":"journal-article","created":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T12:14:59Z","timestamp":1716984899000},"page":"512-517","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Serum Soluble Intercellular Adhesion Molecule-1 (sICAM-1)"],"prefix":"10.4103","volume":"67","author":[{"given":"Amany Ibrahim","family":"Mustafa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel Ali","family":"Ebrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waleed Abdel Lateef","family":"Abel 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