{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:41:29Z","timestamp":1786736489242,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Dermatol"],"published-print":{"date-parts":[[2020]]},"DOI":"10.4103\/ijd.ijd_593_18","type":"journal-article","created":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T00:58:54Z","timestamp":1582592334000},"page":"85","source":"Crossref","is-referenced-by-count":1,"title":["Ablation of DJ-1 enhances oxidative stress by disturbing the function of mitochondria in epidermal melanocytes"],"prefix":"10.4103","volume":"65","author":[{"given":"Xiaolan","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0019-5154.279202-1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.12998\/wjcc.v3.i3.221","article-title":"Highlights in pathogenesis of vitiligo","author":"Mohammed","year":"2015","journal-title":"World J Clin Cases"},{"key":"key-10.4103\/0019-5154.279202-2","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.det.2016.11.014","article-title":"Vitiligo pathogenesis and emerging treatments","author":"Rashighi","year":"2017","journal-title":"Dermatol Clin"},{"key":"key-10.4103\/0019-5154.279202-3","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1034\/j.1600-0749.13.s8.9.x","article-title":"Intrinsic and extrinsic pathomechanisms in vitiligo","author":"Taieb","year":"2000","journal-title":"Pigment Cell Res"},{"key":"key-10.4103\/0019-5154.279202-4","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1034\/j.1600-0749.2003.00070.x","article-title":"A critical appraisal of vitiligo etiologic theories.Is melanocyte loss a melanocytorrhagy?","author":"Gauthier","year":"2003","journal-title":"Pigment Cell Res"},{"key":"key-10.4103\/0019-5154.279202-5","doi-asserted-by":"crossref","unstructured":"Schallreuter KU, Gibbons NC, Zothner C, Abou Elloof MM, Wood JM. Hydrogen peroxide-mediated oxidative stress disrupts calcium binding on calmodulin: More evidence for oxidative stress in vitiligo. Biochem Biophys Res Commun 2007;360:70-5.","DOI":"10.1016\/j.bbrc.2007.05.218"},{"key":"key-10.4103\/0019-5154.279202-6","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/sj.jidsp.5640189","article-title":"In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase","author":"Schallreuter","year":"1999","journal-title":"J Investig Dermatol Symp Proc"},{"key":"key-10.4103\/0019-5154.279202-7","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1007\/s00204-013-1034-4","article-title":"Oxidative stress: The mitochondria-dependent and mitochondria-independent pathways of apoptosis","author":"Sinha","year":"2013","journal-title":"Arch Toxicol"},{"key":"key-10.4103\/0019-5154.279202-8","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1046\/j.0022-202x.2001.01459.x","article-title":"Mitochondrial impairment in peripheral blood mononuclear cells during the active phase of vitiligo","author":"Dell'Anna","year":"2001","journal-title":"J Invest Dermatol"},{"key":"key-10.4103\/0019-5154.279202-9","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1006\/bbrc.1997.6132","article-title":"DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras","author":"Nagakubo","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"key-10.4103\/0019-5154.279202-10","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1093\/hmg\/ddt068","article-title":"The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering","author":"Ottolini","year":"2013","journal-title":"Hum Mol Genet"},{"key":"key-10.4103\/0019-5154.279202-11","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/jnr.21831","article-title":"Mitochondrial localization of DJ-1 leads to enhanced neuroprotection","author":"Junn","year":"2009","journal-title":"J Neurosci Res"},{"key":"key-10.4103\/0019-5154.279202-12","first-page":"42","article-title":"Generation of a human melanocyte cell line by introduction of HPV16 E6 and E7 genes","author":"Le","year":"1997","journal-title":"In Vitro Cell Dev Biol Anim"},{"key":"key-10.4103\/0019-5154.279202-13","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/978-981-10-6583-5_11","article-title":"The role of the antioxidant protein DJ-1 in type 2 diabetes mellitus","author":"Eberhard","year":"2017","journal-title":"Adv Exp Med Biol"},{"key":"key-10.4103\/0019-5154.279202-14","doi-asserted-by":"crossref","first-page":"7415","DOI":"10.1038\/ncomms8415","article-title":"DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice","author":"Shi","year":"2015","journal-title":"Nat Commun"},{"key":"key-10.4103\/0019-5154.279202-15","first-page":"683920","article-title":"Neuroprotective function of DJ-1 in Parkinson's disease","author":"Ariga","year":"2013","journal-title":"Oxid Med Cell Longev"},{"key":"key-10.4103\/0019-5154.279202-16","doi-asserted-by":"crossref","first-page":"9103","DOI":"10.1073\/pnas.0402959101","article-title":"The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization","author":"Canet-Aviles","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key-10.4103\/0019-5154.279202-17","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s11010-013-1884-3","article-title":"Upregulated Parkin expression protects mitochondrial homeostasis in DJ-1 konckdown cells and cells overexpressing the DJ-1 L166P mutation","author":"Chang","year":"2014","journal-title":"Mol Cell Biochem"},{"key":"key-10.4103\/0019-5154.279202-18","doi-asserted-by":"crossref","first-page":"25686","DOI":"10.1074\/jbc.M110.109751","article-title":"Protection of pancreatic beta-cells from various stress conditions is mediated by DJ-1","author":"Inberg","year":"2010","journal-title":"J Biol Chem"},{"key":"key-10.4103\/0019-5154.279202-19","doi-asserted-by":"crossref","first-page":"5551","DOI":"10.1167\/iovs.14-14580","article-title":"Decreased DJ-1 leads to impaired Nrf2-regulated antioxidant defense and increased UV-A-induced apoptosis in corneal endothelial cells","author":"Liu","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"key-10.4103\/0019-5154.279202-20","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.cell.2015.10.001","article-title":"Mitochondrial ROS signaling in organismal homeostasis","author":"Shadel","year":"2015","journal-title":"Cell"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T18:42:34Z","timestamp":1786732954000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.IJD_593_18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020]]}},"alternative-id":["279202"],"URL":"https:\/\/doi.org\/10.4103\/ijd.ijd_593_18","relation":{},"ISSN":["0019-5154"],"issn-type":[{"value":"0019-5154","type":"print"}],"subject":[],"published":{"date-parts":[[2020]]}}}