{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:39:30Z","timestamp":1787071170902,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>Psoriasis is a chronic papulosquamous skin disease that involves immune-mediated cutaneous inflammation and keratinocyte hyperproliferation. The associated immunosuppression in people living with HIV (PLHIV) with psoriasis poses a challenge to the clinician as therapeutic options are limited. Until now, there have been no documented case of apremilast therapy for HIV-associated psoriasis in India. Here, we report a case of HIV-associated psoriasis who achieved Psoriasis Area and Severity Index (PASI) 100 with apremilast therapy.<\/jats:p>","DOI":"10.4103\/ijd.ijd_633_18","type":"journal-article","created":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T05:11:28Z","timestamp":1559020288000},"page":"242-244","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Apremilast in People Living with HIV with Psoriasis Vulgaris: A Case Report"],"prefix":"10.4103","volume":"64","author":[{"given":"Bela J","family":"Shah","sequence":"first","affiliation":[{"name":"From the Department of Dermatology, B J Medical College, Civil Hospital, Ahmedabad, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deval","family":"Mistry","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, B J Medical College, Civil Hospital, Ahmedabad, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navin","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"From the Department of Dermatology, B J Medical College, Civil Hospital, Ahmedabad, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250921","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/S1473-3099(10)70101-8","article-title":"HIV-associated psoriasis: Pathogenesis, clinical features, and management","volume":"10","author":"Morar","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"R2-20250921","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.it.2004.03.006","article-title":"Psoriasis vulgaris: Cutaneous lymphoid tissue supports T-cell activation and \u2018Type 1\u2019 inflammatory gene expression","volume":"25","author":"Lew","year":"2004","journal-title":"Trends Immunol"},{"key":"R3-20250921","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1600-0560.1998.tb01694.x","article-title":"Intraepidermal lymphocytes in psoriatic lesions are activated GMP-17 (TIA-1)+ CD8+ CD3+ CTLs as determined by phenotypic analysis","volume":"25","author":"Austin","year":"1998","journal-title":"J Cutaneous Pathol"},{"key":"R4-20250921","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1111\/jdv.12531","article-title":"Successful treatment of ustekinumab in a severe psoriasis patient with human immunodeficiency virus infection","volume":"29","author":"Saeki","year":"2015","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"R5-20250921","doi-asserted-by":"crossref","first-page":"989","DOI":"10.2340\/00015555-2698","article-title":"Biologic therapies in HIV-infected patients with psoriasis: An Italian experience","volume":"97","author":"Bardazzi","year":"2017","journal-title":"Acta Derm Venereol"},{"key":"R6-20250921","doi-asserted-by":"crossref","first-page":"e481","DOI":"10.1111\/jdv.14301","article-title":"Apremilast for a psoriasis patient with HIV and hepatitis C","volume":"31","author":"Reddy","year":"2017","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"R7-20250921","doi-asserted-by":"crossref","first-page":"e12719","DOI":"10.1111\/dth.12719","article-title":"Apremilast as therapeutic option in a HIV positive patient with severe psoriasis","volume":"31","author":"Sacchelli","year":"2018","journal-title":"Dermatol Ther"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00076423-201964030-00014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:42:33Z","timestamp":1787067753000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00076423-201964030-00014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.4103\/ijd.ijd_633_18","relation":{},"ISSN":["0019-5154","1998-3611"],"issn-type":[{"value":"0019-5154","type":"print"},{"value":"1998-3611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"2018-11-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}