{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:54:39Z","timestamp":1788587679017,"version":"build-2803163510"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The measurement of health-related quality of life (HRQoL) is essential in dermatology, with the DLQI and Skindex-29 being popular tools for assessment. However, the literature comparing the measuring features of these two questionnaires is lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>This study aims to provide a comparison of the measurement properties of DLQI and Skindex-29 in patients with common dermatology conditions such as psoriasis vulgaris (PV), vitiligo vulgaris (VV), leprosy, and acne vulgaris (AV).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this cross-sectional study, the HRQoL of 301 patients with the four dermatological conditions was measured using the DLQI and Skindex-29 questionnaires at a tertiary care centre located in Dehradun, Uttarakhand, India. Statistical analysis included determining ceiling and floor effects, informativity, and criterion validity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean DLQI total scores were: PV (11.03 \u00b1 0.89), VV (4.73 \u00b1 0.78), leprosy (8.97 \u00b1 1.09), and AV (7.79 \u00b1 0.63), and the mean Skindex-29 scores were: PV (37.98 \u00b1 2.82), VV (27.92 \u00b1 2.93), leprosy (45.12 \u00b1 3.63), and AV (27.6 \u00b1 1.08), with a 95% confidence interval. Of the patients with a DLQI score of 0 (n = 66), 64 (96%) had a total score greater than 0 on the Skindex-29. The most troubled areas of HRQoL among patients with a DLQI score of 0 according to the Skindex-29 were item 17 (showing affection; 12.1%), item 9 (worry about scars; 9.1%), item 12, item 13, and item 14 (being ashamed, worrying about worsening, and tending to do things oneself; 7.6%). The ceiling effect was observed in 4.7% of patients for DLQI and 0% for Skindex-29. The floor effect was high for the DLQI total score (22%), whereas Skindex-29 observed only 0.7%. The absolute informativity value of Skindex-29 was 1.66, and that of the DLQI was 1.92. The typical relative informativity value for both was 0.83.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Skindex-29 showed better sensitivity to clinical severity, less floor effect, higher absolute informativity, and better coverage of the \u2018emotion\u2019 domain. Skindex-29 was found to be more effective in detecting minor HRQoL impairment than DLQI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijd.ijd_738_23","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T05:00:09Z","timestamp":1759986009000},"page":"1-11","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["A Comparative Study on the Measurement Properties (Criterion Validity, Informativity, and Floor and Ceiling Effects) of Dermatology Life Quality Index (DLQI) and Skindex-29"],"prefix":"10.4103","volume":"71","author":[{"given":"Aaqid Siraj","family":"Syed","sequence":"first","affiliation":[{"name":"From the Department of Internal Medicine, Mobile Infirmary Medical Centre, Mobile, Alabama, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheenam","family":"Sethi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Himalayan 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