{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:39:34Z","timestamp":1787071174214,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This is a case of acute eosinophilic pneumonia (AEP) in a 21-year-old woman with acne vulgaris who was treated with isotretinoin. During treatment, her blood tests showed normal results until the third month, when there was a slight increase in eosinophil count. In the fifth month of treatment, the patient presented to the pulmonology outpatient clinic with complaints of shortness of breath. Lung CT imaging revealed infiltration in both lungs characterized by ground glass opacities. AEP was diagnosed based on blood and imaging results. Isotretinoin therapy was terminated, and oral steroids were initiated, resulting in the improvement of the patient\u2019s symptoms. The patient had no additional risk factors except for smoking, but she had not started or resumed smoking after quitting. This case report highlights the possibility of hypersensitivity pneumonitis following isotretinoin administration.<\/jats:p>","DOI":"10.4103\/ijd.ijd_75_24","type":"journal-article","created":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T10:24:19Z","timestamp":1726223059000},"page":"487-487","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["A Case Report of Isotretinoin: Acute Eosinophilic Pneumonia, A Rare Adverse Reaction"],"prefix":"10.4103","volume":"69","author":[{"given":"Kadir","family":"K\u00fc\u00e7\u00fck","sequence":"first","affiliation":[{"name":"From the Dermatology and Venerology Clinics, Hitit University \u00c7orum Erol Ol\u00e7ok Medical Training Hospital, \u00c7orum Merkez, \u00c7orum, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,10,29]]},"reference":[{"key":"R1-20241101","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.iac.2023.01.002","article-title":"Eosinophilic lung diseases","volume":"43","author":"Cottin","year":"2023","journal-title":"Immunol Allergy Clin North Am"},{"key":"R2-20241101","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1164\/rccm.201710-1967CI","article-title":"Acute eosinophilic pneumonia. causes, diagnosis, and management","volume":"197","author":"De Giacomi","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"key":"R3-20241101","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0272-5231(03)00141-2","article-title":"Drug-induced eosinophilic lung disease","volume":"25","author":"Allen","year":"2004","journal-title":"Clin Chest Med"},{"key":"R4-20241101","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1378\/chest.07-2669","article-title":"Alterations in smoking habits are associated with acute eosinophilic pneumonia","volume":"133","author":"Uchiyama","year":"2008","journal-title":"Chest"},{"key":"R5-20241101","first-page":"631","article-title":"Lung disease induced by isotretinoin","volume":"12","author":"Oliviero","year":"1995","journal-title":"Rev Mal Respir"},{"key":"R6-20241101","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0140-6736(89)90026-3","article-title":"Isotretinoin and eosinophilic pleural effusion","volume":"333","author":"Bunker","year":"1989","journal-title":"Lancet"},{"key":"R7-20241101","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/S0012-3692(15)46503-1","article-title":"Isotretinoin-related eosinophilic pleural effusion","volume":"110","author":"Milleron","year":"1996","journal-title":"Chest"},{"key":"R8-20241101","article-title":"A severe case of isotretinoin induced eosinophilic pneumonia and pericardial effusion, a case report","author":"Kampman","journal-title":"Curr Drug Saf 2024"},{"key":"R9-20241101","first-page":"e42649","article-title":"Isotretinoin as a possible cause for eosinophilic esophagitis and eosinophilic gastroenteritis:A case report","volume":"15","author":"Nizam","year":"2023","journal-title":"Cureus"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.ijd_75_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:42:35Z","timestamp":1787067755000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.ijd_75_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,29]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/ijd.ijd_75_24","relation":{},"ISSN":["0019-5154","1998-3611"],"issn-type":[{"value":"0019-5154","type":"print"},{"value":"1998-3611","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,29]]},"assertion":[{"value":"2024-01-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}