{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:23:18Z","timestamp":1787772198745,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Griscelli syndrome (GS) is a very rare autosomal recessive disorder, belongs to group of \u201csilvery hair syndromes\u201d which includes Chediak-Higashi syndrome (CHS) and Elejalde syndrome. Hair light microscopy helps in the differentiation of GS and CHS, as both manifest with clinical features. Trichoscopy is useful in the diagnosis of many hair shaft disorders. Here, authors describe the trichoscopic features of GS in skin of color.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This was an observational study conducted in a private dermatology clinic and in a tertiary care hospital. A total of 5 cases of suspected GS were referred by pediatrician. Consent was obtained. The demographic data in terms of age, gender, consanguinity, and clinical history was documented. Trichoscopic examination was performed with FotoFinder videodermoscope with 20\u00d7 magnification, the clinical images were captured with Medicam 1000. Trichoscopy showed large and irregular pigment clumps in 4 cases. One case demonstrated hypopigmentation of hair without pigment clumps [Figure 3a].<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Trichoscopy showed large and irregular pigment clumps in 4 cases. One case demonstrated hypopigmentation of hair without pigment clumps.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Trichoscopy shows characteristic features GS. It is a useful method when facility for light or polarized microscope is unavailable.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ijd.ijd_866_22","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T01:47:09Z","timestamp":1715737629000},"page":"192-194","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Griscelli Syndrome in Skin of Color"],"prefix":"10.4103","volume":"68","author":[{"given":"Swapnil D.","family":"Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balachandra S.","family":"Ankad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sankappanavara V.","family":"Smitha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20240829","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/0002-9343(78)90858-6","article-title":"A syndrome associating partial albinism and immunodeficiency","volume":"65","author":"Griscelli","year":"1978","journal-title":"Am J Med"},{"key":"R2-10-20240829","doi-asserted-by":"crossref","first-page":"46","DOI":"10.4103\/0974-7753.82124","article-title":"Light microscopy of the hair: A simple tool to \u201cuntangle\u201d hair disorders","volume":"3","author":"Adya","year":"2011","journal-title":"Int J Trichology"},{"key":"R3-10-20240829","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1590\/S1807-59322006000400009","article-title":"Polarized light microscopy of hair shafts aids in the differential diagnosis of Ch\u00e9diak-Higashi and Griscelli-Prunieras syndromes","volume":"61","author":"Valente","year":"2006","journal-title":"Clinics (Sao Paulo"},{"key":"R4-10-20240829","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3315\/jdcr.2008.1009","article-title":"Trichoscopy in genetic hair shaft abnormalities","volume":"2","author":"Rakowska","year":"2008","journal-title":"J Dermatol Case Rep"},{"key":"R5-10-20240829","doi-asserted-by":"crossref","first-page":"83","DOI":"10.4103\/0974-7753.96910","article-title":"Silvery grey hair: Clue to diagnose immunodeficiency","volume":"4","author":"Sahana","year":"2012","journal-title":"Int J Trichol"},{"key":"R6-10-20240829","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1159\/000452165","article-title":"\u201cRoad-dividing line\u201d- Like pigmentation of hair as a diagnostic clue for Grescelli syndrome","volume":"2","author":"Katoulis","year":"2017","journal-title":"Skin Appendage Disord"},{"key":"R7-10-20240829","doi-asserted-by":"crossref","first-page":"524","DOI":"10.4103\/0019-5154.159662","article-title":"Chediak-Higashi syndrome: A case series from Karnataka, India","volume":"60","author":"Rudramurthy","year":"2015","journal-title":"Indian J Dermatol"}],"container-title":["Indian Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.ijd_866_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:32:44Z","timestamp":1787769164000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ijd.ijd_866_22"}},"subtitle":["A Trichoscopic Perspective"],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/ijd.ijd_866_22","relation":{},"ISSN":["0019-5154"],"issn-type":[{"value":"0019-5154","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]}}}